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The map label for this gene is yngE [H]

Identifier: 54294714

GI number: 54294714

Start: 2003646

End: 2005253

Strand: Direct

Name: yngE [H]

Synonym: lpl1791

Alternate gene names: 54294714

Gene position: 2003646-2005253 (Clockwise)

Preceding gene: 54294713

Following gene: 54294715

Centisome position: 59.89

GC content: 43.22

Gene sequence:

>1608_bases
ATGGCTAAGTTAACTACTCAAATCAATACCAGCAGTCAGGAATTCAAAAATAATCAGGCGAATATGCAAGCATTGGTTAC
TGATTTAAGAGAAAAAATACATCAAATCTCTCTGGGTGGAGATGAAAAAGCGCGTACCAAACATCAACAACAAGGCAAAC
TACTTCCGAGAGAACGCTTACACCAGTTGCTGGATCCAGGTAGTCCTTTTCTTGAGCTATCTCAACTTGCTGCCTACCAA
GTCTATGAAGACTCGATACCCGCTGCAGGAATAATCACTGGCATTGGCAGAGTGGCAGGAAACGAATGTGTGATTGTGGT
CAACGATGCTACTGTTAAAGGCGGAACATATTATCCTTTGACCGTAAAAAAACACTTAAGAGCACAAGAAATTGCATTGA
TAAACCATCTTCCATGCATCTATCTGGTGGATTCAGGAGGTGCCTTTCTACCGCTTCAAGATCAGGTCTTCGCCGATAAA
GAACATTTTGGGCGTGTTTTTTATAATCAAGCGCAAATGTCAGCATTAAATATTCCTCAAATAGCCGTGGTTATGGGATC
TTGTACGGCGGGAGGAGCTTATGTACCAGCCATGGCTGATGAATCTATTATGGTCAAGAATCAGGCAACCATATTCCTTG
GAGGACCTCCTCTCGTTAAAGCAGCAACAGGAGAAATAATCAGCGCGGAAGAATTAGGAGGAGCCGAAGTTCACTGTCGC
CACTCAGGAGTATCTGATCATTATGCGGAAAATGACGCTCACGCGCTTCATTTAGCGCGAGCCGCCATTAGCAATTTAAA
TCGTAAAAAACCAGATTCCATTCATAGGGCGGATACAGTTCCTCCTCTTTATGATAGCGAAGATCTTACCGGAATAATTC
CCACTGACCCTAGAAAGCCTTTTGATATAAGAGAAATTATTGCTCGAGTGGTAGATGGTTCAGAGTTTGATGAATTCAAA
GCACTTTTTGGAACAACCCTGGTTTGCGGTTTTGCTCGCCTATATGGATATCCTATAGGGATTATTGCTAATAATGGCAT
ACTTTTTAGTGAAAGTGCGCAAAAGGGCAGCCATTTCATAGAGCTGTGCTGTCAACGTAAAATACCGCTTGTATTCCTGC
AAAATATTACAGGATTTATGGTCGGCTCCAAATACGAAGCATCAGGTATTGCAAAACATGGAGCCAAAATGGTGACAGCA
GTTGCCAATGCTAATGTACCCAAATTTACCATCATTGTTGGTGGCAGTTTTGGAGCAGGTAATTATGCCATGTGTGGCCG
GGCATATGCTCCTCGTTTCCTATGGGCCTGGCCTAATGCACGCATCTCAGTAATGGGTGGAGAACAAGCAGCGAATGTTC
TGGCGCAAATTACCAGGGAGAAATATGCAAAGCAAGGAAAGGAATGGTCACTCGAAGAAGAAGAACAATTTAAAACTCAA
ATGAGAAGTCAGTATGAAACTCAGGGAAATCCTTACTATGCCAGTGCCAGGCTTTGGGATGATGGAGTCATCGCCCCTCA
GGATACACGCAAAATACTCGGACTTGGATTATCTGCAGCCTTAAATGCACCGATTGAGGATACTCGTTTCGGTGTATTTC
GCATGTAA

Upstream 100 bases:

>100_bases
GGCACTCAAAGGAAAAGACATGCCCCATTTTATTGCGATTGTCTGGATAATATGGACCATCATAGTCTTGAGTGATATTT
TGATTCGGTAAGGATAAAAA

Downstream 100 bases:

>100_bases
AAGGAAAGGAACAATAGGCATGAGTGATTTATTATATGAAATTCAAGATAAAGTAGGTTTACTTACTATGAATCGAATTA
GCAAGCATAATGCGTTCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MAKLTTQINTSSQEFKNNQANMQALVTDLREKIHQISLGGDEKARTKHQQQGKLLPRERLHQLLDPGSPFLELSQLAAYQ
VYEDSIPAAGIITGIGRVAGNECVIVVNDATVKGGTYYPLTVKKHLRAQEIALINHLPCIYLVDSGGAFLPLQDQVFADK
EHFGRVFYNQAQMSALNIPQIAVVMGSCTAGGAYVPAMADESIMVKNQATIFLGGPPLVKAATGEIISAEELGGAEVHCR
HSGVSDHYAENDAHALHLARAAISNLNRKKPDSIHRADTVPPLYDSEDLTGIIPTDPRKPFDIREIIARVVDGSEFDEFK
ALFGTTLVCGFARLYGYPIGIIANNGILFSESAQKGSHFIELCCQRKIPLVFLQNITGFMVGSKYEASGIAKHGAKMVTA
VANANVPKFTIIVGGSFGAGNYAMCGRAYAPRFLWAWPNARISVMGGEQAANVLAQITREKYAKQGKEWSLEEEEQFKTQ
MRSQYETQGNPYYASARLWDDGVIAPQDTRKILGLGLSAALNAPIEDTRFGVFRM

Sequences:

>Translated_535_residues
MAKLTTQINTSSQEFKNNQANMQALVTDLREKIHQISLGGDEKARTKHQQQGKLLPRERLHQLLDPGSPFLELSQLAAYQ
VYEDSIPAAGIITGIGRVAGNECVIVVNDATVKGGTYYPLTVKKHLRAQEIALINHLPCIYLVDSGGAFLPLQDQVFADK
EHFGRVFYNQAQMSALNIPQIAVVMGSCTAGGAYVPAMADESIMVKNQATIFLGGPPLVKAATGEIISAEELGGAEVHCR
HSGVSDHYAENDAHALHLARAAISNLNRKKPDSIHRADTVPPLYDSEDLTGIIPTDPRKPFDIREIIARVVDGSEFDEFK
ALFGTTLVCGFARLYGYPIGIIANNGILFSESAQKGSHFIELCCQRKIPLVFLQNITGFMVGSKYEASGIAKHGAKMVTA
VANANVPKFTIIVGGSFGAGNYAMCGRAYAPRFLWAWPNARISVMGGEQAANVLAQITREKYAKQGKEWSLEEEEQFKTQ
MRSQYETQGNPYYASARLWDDGVIAPQDTRKILGLGLSAALNAPIEDTRFGVFRM
>Mature_534_residues
AKLTTQINTSSQEFKNNQANMQALVTDLREKIHQISLGGDEKARTKHQQQGKLLPRERLHQLLDPGSPFLELSQLAAYQV
YEDSIPAAGIITGIGRVAGNECVIVVNDATVKGGTYYPLTVKKHLRAQEIALINHLPCIYLVDSGGAFLPLQDQVFADKE
HFGRVFYNQAQMSALNIPQIAVVMGSCTAGGAYVPAMADESIMVKNQATIFLGGPPLVKAATGEIISAEELGGAEVHCRH
SGVSDHYAENDAHALHLARAAISNLNRKKPDSIHRADTVPPLYDSEDLTGIIPTDPRKPFDIREIIARVVDGSEFDEFKA
LFGTTLVCGFARLYGYPIGIIANNGILFSESAQKGSHFIELCCQRKIPLVFLQNITGFMVGSKYEASGIAKHGAKMVTAV
ANANVPKFTIIVGGSFGAGNYAMCGRAYAPRFLWAWPNARISVMGGEQAANVLAQITREKYAKQGKEWSLEEEEQFKTQM
RSQYETQGNPYYASARLWDDGVIAPQDTRKILGLGLSAALNAPIEDTRFGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=536, Percent_Identity=65.1119402985075, Blast_Score=731, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=490, Percent_Identity=31.6326530612245, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI295821216, Length=510, Percent_Identity=30.3921568627451, Blast_Score=222, Evalue=8e-58,
Organism=Homo sapiens, GI310133460, Length=146, Percent_Identity=60.958904109589, Blast_Score=165, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17552936, Length=535, Percent_Identity=61.4953271028037, Blast_Score=707, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=485, Percent_Identity=31.7525773195876, Blast_Score=241, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI25147359, Length=485, Percent_Identity=31.7525773195876, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24586065, Length=549, Percent_Identity=63.752276867031, Blast_Score=726, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 58404; Mature: 58273

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLTTQINTSSQEFKNNQANMQALVTDLREKIHQISLGGDEKARTKHQQQGKLLPRERL
CCEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
HQLLDPGSPFLELSQLAAYQVYEDSIPAAGIITGIGRVAGNECVIVVNDATVKGGTYYPL
HHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCEECCCEEEEE
TVKKHLRAQEIALINHLPCIYLVDSGGAFLPLQDQVFADKEHFGRVFYNQAQMSALNIPQ
EHHHHCCHHHHHHHHCCCEEEEECCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHCCCCE
IAVVMGSCTAGGAYVPAMADESIMVKNQATIFLGGPPLVKAATGEIISAEELGGAEVHCR
EEEEEECCCCCCEEECCCCCCEEEEECCEEEEECCCCEEEECCCCEEEHHHCCCCEEEEE
HSGVSDHYAENDAHALHLARAAISNLNRKKPDSIHRADTVPPLYDSEDLTGIIPTDPRKP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCEECCCCCCCC
FDIREIIARVVDGSEFDEFKALFGTTLVCGFARLYGYPIGIIANNGILFSESAQKGSHFI
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCHHHH
ELCCQRKIPLVFLQNITGFMVGSKYEASGIAKHGAKMVTAVANANVPKFTIIVGGSFGAG
HHHHCCCCCEEEECCCCCEEECCCCCCCCHHHHCHHEEEEECCCCCCEEEEEEECCCCCC
NYAMCGRAYAPRFLWAWPNARISVMGGEQAANVLAQITREKYAKQGKEWSLEEEEQFKTQ
CHHHCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MRSQYETQGNPYYASARLWDDGVIAPQDTRKILGLGLSAALNAPIEDTRFGVFRM
HHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCCCEECC
>Mature Secondary Structure 
AKLTTQINTSSQEFKNNQANMQALVTDLREKIHQISLGGDEKARTKHQQQGKLLPRERL
CEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
HQLLDPGSPFLELSQLAAYQVYEDSIPAAGIITGIGRVAGNECVIVVNDATVKGGTYYPL
HHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCEECCCEEEEE
TVKKHLRAQEIALINHLPCIYLVDSGGAFLPLQDQVFADKEHFGRVFYNQAQMSALNIPQ
EHHHHCCHHHHHHHHCCCEEEEECCCCEEECCCHHHHCCHHHHHHHHHHHHHHHHCCCCE
IAVVMGSCTAGGAYVPAMADESIMVKNQATIFLGGPPLVKAATGEIISAEELGGAEVHCR
EEEEEECCCCCCEEECCCCCCEEEEECCEEEEECCCCEEEECCCCEEEHHHCCCCEEEEE
HSGVSDHYAENDAHALHLARAAISNLNRKKPDSIHRADTVPPLYDSEDLTGIIPTDPRKP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCEECCCCCCCC
FDIREIIARVVDGSEFDEFKALFGTTLVCGFARLYGYPIGIIANNGILFSESAQKGSHFI
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCHHHH
ELCCQRKIPLVFLQNITGFMVGSKYEASGIAKHGAKMVTAVANANVPKFTIIVGGSFGAG
HHHHCCCCCEEEECCCCCEEECCCCCCCCHHHHCHHEEEEECCCCCCEEEEEEECCCCCC
NYAMCGRAYAPRFLWAWPNARISVMGGEQAANVLAQITREKYAKQGKEWSLEEEEQFKTQ
CHHHCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MRSQYETQGNPYYASARLWDDGVIAPQDTRKILGLGLSAALNAPIEDTRFGVFRM
HHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCHHHHCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]