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The map label for this gene is mrp [H]

Identifier: 54294700

GI number: 54294700

Start: 1988780

End: 1989853

Strand: Direct

Name: mrp [H]

Synonym: lpl1777

Alternate gene names: 54294700

Gene position: 1988780-1989853 (Clockwise)

Preceding gene: 54294699

Following gene: 54294701

Centisome position: 59.44

GC content: 40.69

Gene sequence:

>1074_bases
ATGACTATTGAAGATACAGTAATTAAGTTAATTGGCTCATTAAAGGATCCCTTGCTTGATCTTACTGGCAAGGAAATGAA
TCTACAGTACAAAATAACAACTAGCAACCAGGCTATTCATGTTGTCTTGACTGCCGGATATCCTACCTCTTTGTTAGAAA
CGAGCTATAAACCAATAGTACAGAAAATAGTTCAAGATGAATTCCCCAATTACCAAGTTACTATTTCTATTCAACAATTC
ATAAAAGCGCATAAAACTCAGTTGACAGGTAAAGCCCTGCGAGGAGTAAAGAATACTATCGCAGTGGCCTCTGGCAAAGG
AGGCGTCGGAAAGTCTACTGTCACAGTAAATCTTGCAGCAGCATTGGCAAAACTGGGCGCTCGAGTCGGCATTTTGGATG
CGGATATTTATGGACCAAGCATACCATTGATGCTTGGTGAAACAAAACCTGTACAAGTAAAAGATAATTGCTACATACCG
GTTGAAGCTCATGGCATGCAGGCCATGTCTATTGGCTACTTGACCGATACAAACCAGGCATTAATTTGGAGAGGTCCTAT
GCTAGCCAAGTCTTTAATCCAAATGTTAGACATCACTCTTTGGAATGAATTGGATTATTTATTCATAGATCTACCACCTG
GCACTGGAGATATTCAACTCACTTTGGTACAAAAAATTCCTTTAACCTCTGCCATAGTAGTTACTACTCCTCAAAATGTC
GCAACTTTAGATGCCCAAAAAGCAATAACCATGTTTTCCAGAACAGGCATTGACGTACTTGGAATAATAGAAAATATGTC
CACCCACATTTGTAGCCATTGTGGTCATCAAGAAGCAATCTTTGGTAGAGGTGGTGCAGCTGCGCTGTGTGACGCCTATC
AATGTACATTATTAGGTCAACTGCCGCTGGACAGCCATGTACGTAGACATTGCGATGAGGGAGTTCCCACGGCAACACAT
TCATCAAATCAATTAACTGACACCTTTATTAAAACAGCGATGCGAACTGCAATTGAGCTCAGCAAGAAACCCATAAACTA
TGCTGACAGATTTCCAAAGATAGTTGTGGAATAG

Upstream 100 bases:

>100_bases
GATGCATTCATCAACCCAGCAAAAACGAATAGTAATGGTACTAGTGATTAGCCGAGACCTAAGTTATCATTACCTATTTA
TTTTCATACCAGGCTAAAAA

Downstream 100 bases:

>100_bases
AAGTAATAGCTTTTCTACTATGTATTATTCCCTTCAGATGAGTATATAATACATAAAAATTGAGTTTGCCACCTCAAAGA
TAACCAAGCTCACAAAAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTIEDTVIKLIGSLKDPLLDLTGKEMNLQYKITTSNQAIHVVLTAGYPTSLLETSYKPIVQKIVQDEFPNYQVTISIQQF
IKAHKTQLTGKALRGVKNTIAVASGKGGVGKSTVTVNLAAALAKLGARVGILDADIYGPSIPLMLGETKPVQVKDNCYIP
VEAHGMQAMSIGYLTDTNQALIWRGPMLAKSLIQMLDITLWNELDYLFIDLPPGTGDIQLTLVQKIPLTSAIVVTTPQNV
ATLDAQKAITMFSRTGIDVLGIIENMSTHICSHCGHQEAIFGRGGAAALCDAYQCTLLGQLPLDSHVRRHCDEGVPTATH
SSNQLTDTFIKTAMRTAIELSKKPINYADRFPKIVVE

Sequences:

>Translated_357_residues
MTIEDTVIKLIGSLKDPLLDLTGKEMNLQYKITTSNQAIHVVLTAGYPTSLLETSYKPIVQKIVQDEFPNYQVTISIQQF
IKAHKTQLTGKALRGVKNTIAVASGKGGVGKSTVTVNLAAALAKLGARVGILDADIYGPSIPLMLGETKPVQVKDNCYIP
VEAHGMQAMSIGYLTDTNQALIWRGPMLAKSLIQMLDITLWNELDYLFIDLPPGTGDIQLTLVQKIPLTSAIVVTTPQNV
ATLDAQKAITMFSRTGIDVLGIIENMSTHICSHCGHQEAIFGRGGAAALCDAYQCTLLGQLPLDSHVRRHCDEGVPTATH
SSNQLTDTFIKTAMRTAIELSKKPINYADRFPKIVVE
>Mature_356_residues
TIEDTVIKLIGSLKDPLLDLTGKEMNLQYKITTSNQAIHVVLTAGYPTSLLETSYKPIVQKIVQDEFPNYQVTISIQQFI
KAHKTQLTGKALRGVKNTIAVASGKGGVGKSTVTVNLAAALAKLGARVGILDADIYGPSIPLMLGETKPVQVKDNCYIPV
EAHGMQAMSIGYLTDTNQALIWRGPMLAKSLIQMLDITLWNELDYLFIDLPPGTGDIQLTLVQKIPLTSAIVVTTPQNVA
TLDAQKAITMFSRTGIDVLGIIENMSTHICSHCGHQEAIFGRGGAAALCDAYQCTLLGQLPLDSHVRRHCDEGVPTATHS
SNQLTDTFIKTAMRTAIELSKKPINYADRFPKIVVE

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=281, Percent_Identity=38.7900355871886, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI6912540, Length=231, Percent_Identity=41.991341991342, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI118572611, Length=233, Percent_Identity=38.1974248927039, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI87082045, Length=252, Percent_Identity=55.1587301587302, Blast_Score=277, Evalue=8e-76,
Organism=Caenorhabditis elegans, GI25143050, Length=256, Percent_Identity=39.453125, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322188, Length=223, Percent_Identity=39.4618834080717, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321347, Length=264, Percent_Identity=39.3939393939394, Blast_Score=159, Evalue=6e-40,
Organism=Drosophila melanogaster, GI221511043, Length=254, Percent_Identity=39.3700787401575, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24667611, Length=223, Percent_Identity=45.2914798206278, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI19921440, Length=268, Percent_Identity=37.6865671641791, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38726; Mature: 38594

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEDTVIKLIGSLKDPLLDLTGKEMNLQYKITTSNQAIHVVLTAGYPTSLLETSYKPIV
CCCHHHHHHHHHHHCCHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCHHHHHCCHHHHH
QKIVQDEFPNYQVTISIQQFIKAHKTQLTGKALRGVKNTIAVASGKGGVGKSTVTVNLAA
HHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCEEEEEHHH
ALAKLGARVGILDADIYGPSIPLMLGETKPVQVKDNCYIPVEAHGMQAMSIGYLTDTNQA
HHHHHCCEEEEEECCCCCCCCCEEECCCCCEEECCCEEEEEECCCCEEEEEEEEECCCCE
LIWRGPMLAKSLIQMLDITLWNELDYLFIDLPPGTGDIQLTLVQKIPLTSAIVVTTPQNV
EEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCCCEEEEEECCCCC
ATLDAQKAITMFSRTGIDVLGIIENMSTHICSHCGHQEAIFGRGGAAALCDAYQCTLLGQ
EECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCEEEEEEEC
LPLDSHVRRHCDEGVPTATHSSNQLTDTFIKTAMRTAIELSKKPINYADRFPKIVVE
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEECC
>Mature Secondary Structure 
TIEDTVIKLIGSLKDPLLDLTGKEMNLQYKITTSNQAIHVVLTAGYPTSLLETSYKPIV
CCHHHHHHHHHHHCCHHHCCCCCEEEEEEEEEECCCEEEEEEECCCCHHHHHCCHHHHH
QKIVQDEFPNYQVTISIQQFIKAHKTQLTGKALRGVKNTIAVASGKGGVGKSTVTVNLAA
HHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCEEEEEHHH
ALAKLGARVGILDADIYGPSIPLMLGETKPVQVKDNCYIPVEAHGMQAMSIGYLTDTNQA
HHHHHCCEEEEEECCCCCCCCCEEECCCCCEEECCCEEEEEECCCCEEEEEEEEECCCCE
LIWRGPMLAKSLIQMLDITLWNELDYLFIDLPPGTGDIQLTLVQKIPLTSAIVVTTPQNV
EEEECHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEECCCCEEEEEECCCCC
ATLDAQKAITMFSRTGIDVLGIIENMSTHICSHCGHQEAIFGRGGAAALCDAYQCTLLGQ
EECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCEEEEEEEC
LPLDSHVRRHCDEGVPTATHSSNQLTDTFIKTAMRTAIELSKKPINYADRFPKIVVE
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]