| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is cyaA [H]
Identifier: 54294627
GI number: 54294627
Start: 1901574
End: 1903850
Strand: Direct
Name: cyaA [H]
Synonym: lpl1703
Alternate gene names: 54294627
Gene position: 1901574-1903850 (Clockwise)
Preceding gene: 54294626
Following gene: 54294628
Centisome position: 56.84
GC content: 37.55
Gene sequence:
>2277_bases GTGTTTAAGAGTAGCAAAAGGATAATTTTCGTGAATAAATTAACTCTTTATTTCCCTCAATTCCTCAATCACATAAAGTG GACTGAGTTTTTCTTGGGGCTGGCAGTAACCCTTTTAGTGTTACTAACCTTGTTCTTTAATGTTCCTCCACTCAATTCGC TAATATCCCAATTTGAAGGAAGAGTTTATGATCAAATAATTAACTTTAATTGGCATTCAAAACCTGAAAACCTTAAAGTT ATTATCATAGACATTGATGAGAAATCATTAGAACAAGAAGGAAGATGGCCATGGCCAAGAAGTAAAATAGCTGAATTATT AAATAAATTACAAGAAAATGGTGTAGTCACTGTTGGTTTCGATATAGTCATGTCAGAAGCGGAAACGAATTATGCTTTGG GCCTCATAGAAAAACTGAGTCAATTTTCTGGAAAAATGACAACTGATCAAAAACAGTTGATTGCCACATTAAACAGCGTT GCAAATCAGGTTGATAATGATCAAACGCTTGTTAACGCTTTAGGCAAAAATAATGCGATACTTGGTTTTTTTTTTCATAA TAGCGAAGGCATTAGAAAAGGCTCTTTACCGCCACCATTAAGAGATACTGACAGCAACCCCCTCCTGGCAAGCAAGCTGT CAGTGTATCAATTTACTAATTTCAACGGTAATTTGGCCGCATTTACAGCGGCTGCAACTTCTGGAGGGTTTGTTACAAAT TTACCCGACAAAGATGGGGTTGTAAGACATGCACTTTTATTGGCCAATTATAAAAACAACCTCTATCCCAGTTTATCTTT GGCAATAGCAATGAATTACCTCTTAACTGACAAGGTTAATCTGAAAAAATATAACAACGAATTGACAGGTATAGAATTAG ATGGGTTACAAATTCCTACAAATAGAAAAGGTCAAATTCTTATTCCATTTTGGGGAGGCCCCGGAACACTAAATTACTAT TCAGCGACTGACATATTGAACAACCAATTCAATCCCGACGAATTGGCTGGGAGTATCGCCTTAGTTGGCTCATCTATAAC ACTCTTATCTGATTTACACCATACACCAGTTGCCCAATTATTTCCTGGGGTTGAAATAGTGGGTAATATCGTAAAAGGAC TGGTAGAACAAAAAATTCCCCGAGAATTTGACTGGGAATCATTGCAAGGAAAACTTTGTTTAGTGATTTTTGGCTTATTA TTTGCGCTTGTATTTTCTTCTATTGGTATTTTTGGCAAATTATTAATATTTTTTATAACAACCATAGTAATATTAACAAA TACAGTTATCCTGTTCGTATTTTACAACAATTACGTCCCCCCTGCATTTTTATTAACCATCACTACCTTGCAAACTTTTG TTAATTTTTCCTATTCATATGTCATTGAAAAGAGGCAAAAAAGACGAATAAGCGAATTGTTCGGTCAATACGTACCCAAA GAATACGTCAAAGAACTAATAGAGCATCCCGAACACCATACTATGGAGGGGCTGAATCGTGAAATGACAGTTCTGTTTAC TGACATACGCAATTTTACAACAATTAGCGAAACTCTTGGTGCAGGCGGTGTAAAACAGCTGTTAAATTCATTTTTCACCC CAATGACCAAAATCATTTTTGAGCATAGAGGAACCATTGATAAATACGTTGGAGATATGATAGTGGCATTCTGGGGAGCA CCAATAGAAGACAAGGAGCATGCGAATCACGCCGTTTTGTGTTCTCTTTCCTGCTTTGAGCACTTGCCTCAAATTAATAC CCATTTATTGGAGCATGGGCTGCCACAAGTTAATATTGGAGTAGGTATAGCAACTGGTCCTATGAACGTTGGTGACATGG GTTCTGAGTTTCGTCGAGCCTATACTGTTCTTGGCGATACCGTTAACCTCGCATCCAGGCTAGAGAGTCTAACCAAATTC TATCAAGTGAATATCCTGGTCAGTGACAAAACTCGCTCCCACCTGGATAGCATATTATGGCGTACCGTTGACAAAGTGGC AGTCAAAGGTCGTAAAAGTCCATTGACTATTTACCAACCTCTAGGTATTGTTGAACAAGCCTCTGCAAGACTTCTGCAGG AGCAGGAAAAATACGAAACGGCATTAGCTCACTATTACAATCAGGATTGGCTTGTCGCTGAGATTATCTTCAATGAGTTA AAAAATGTAAACCCTAAAATTTATTTGTACCAAATGTATTTGGAAAGAATAGCAGCATTCAAAAAAAAGCGGCCTTCGCC TGACTGGGATGGAGTGTATGTTCATAGAAGCAAGTAA
Upstream 100 bases:
>100_bases GGAACAAATATACCTGTGATCTGCCAGGTTTAAAAACATTATTTCTGCCCTTCCCTCGAAGACTATATACTGATTAATAA AGAGGACGCTCTTTCATCTT
Downstream 100 bases:
>100_bases GATCAAGAAGAAACTTTAAATACTGCAATAGGAAGGATTATGAAAACAATTAGGCTGTTTATGTTATCAATAATTGCACA TTTTTTATTGACCTGCTCAG
Product: hypothetical protein
Products: NA
Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]
Number of amino acids: Translated: 758; Mature: 758
Protein sequence:
>758_residues MFKSSKRIIFVNKLTLYFPQFLNHIKWTEFFLGLAVTLLVLLTLFFNVPPLNSLISQFEGRVYDQIINFNWHSKPENLKV IIIDIDEKSLEQEGRWPWPRSKIAELLNKLQENGVVTVGFDIVMSEAETNYALGLIEKLSQFSGKMTTDQKQLIATLNSV ANQVDNDQTLVNALGKNNAILGFFFHNSEGIRKGSLPPPLRDTDSNPLLASKLSVYQFTNFNGNLAAFTAAATSGGFVTN LPDKDGVVRHALLLANYKNNLYPSLSLAIAMNYLLTDKVNLKKYNNELTGIELDGLQIPTNRKGQILIPFWGGPGTLNYY SATDILNNQFNPDELAGSIALVGSSITLLSDLHHTPVAQLFPGVEIVGNIVKGLVEQKIPREFDWESLQGKLCLVIFGLL FALVFSSIGIFGKLLIFFITTIVILTNTVILFVFYNNYVPPAFLLTITTLQTFVNFSYSYVIEKRQKRRISELFGQYVPK EYVKELIEHPEHHTMEGLNREMTVLFTDIRNFTTISETLGAGGVKQLLNSFFTPMTKIIFEHRGTIDKYVGDMIVAFWGA PIEDKEHANHAVLCSLSCFEHLPQINTHLLEHGLPQVNIGVGIATGPMNVGDMGSEFRRAYTVLGDTVNLASRLESLTKF YQVNILVSDKTRSHLDSILWRTVDKVAVKGRKSPLTIYQPLGIVEQASARLLQEQEKYETALAHYYNQDWLVAEIIFNEL KNVNPKIYLYQMYLERIAAFKKKRPSPDWDGVYVHRSK
Sequences:
>Translated_758_residues MFKSSKRIIFVNKLTLYFPQFLNHIKWTEFFLGLAVTLLVLLTLFFNVPPLNSLISQFEGRVYDQIINFNWHSKPENLKV IIIDIDEKSLEQEGRWPWPRSKIAELLNKLQENGVVTVGFDIVMSEAETNYALGLIEKLSQFSGKMTTDQKQLIATLNSV ANQVDNDQTLVNALGKNNAILGFFFHNSEGIRKGSLPPPLRDTDSNPLLASKLSVYQFTNFNGNLAAFTAAATSGGFVTN LPDKDGVVRHALLLANYKNNLYPSLSLAIAMNYLLTDKVNLKKYNNELTGIELDGLQIPTNRKGQILIPFWGGPGTLNYY SATDILNNQFNPDELAGSIALVGSSITLLSDLHHTPVAQLFPGVEIVGNIVKGLVEQKIPREFDWESLQGKLCLVIFGLL FALVFSSIGIFGKLLIFFITTIVILTNTVILFVFYNNYVPPAFLLTITTLQTFVNFSYSYVIEKRQKRRISELFGQYVPK EYVKELIEHPEHHTMEGLNREMTVLFTDIRNFTTISETLGAGGVKQLLNSFFTPMTKIIFEHRGTIDKYVGDMIVAFWGA PIEDKEHANHAVLCSLSCFEHLPQINTHLLEHGLPQVNIGVGIATGPMNVGDMGSEFRRAYTVLGDTVNLASRLESLTKF YQVNILVSDKTRSHLDSILWRTVDKVAVKGRKSPLTIYQPLGIVEQASARLLQEQEKYETALAHYYNQDWLVAEIIFNEL KNVNPKIYLYQMYLERIAAFKKKRPSPDWDGVYVHRSK >Mature_758_residues MFKSSKRIIFVNKLTLYFPQFLNHIKWTEFFLGLAVTLLVLLTLFFNVPPLNSLISQFEGRVYDQIINFNWHSKPENLKV IIIDIDEKSLEQEGRWPWPRSKIAELLNKLQENGVVTVGFDIVMSEAETNYALGLIEKLSQFSGKMTTDQKQLIATLNSV ANQVDNDQTLVNALGKNNAILGFFFHNSEGIRKGSLPPPLRDTDSNPLLASKLSVYQFTNFNGNLAAFTAAATSGGFVTN LPDKDGVVRHALLLANYKNNLYPSLSLAIAMNYLLTDKVNLKKYNNELTGIELDGLQIPTNRKGQILIPFWGGPGTLNYY SATDILNNQFNPDELAGSIALVGSSITLLSDLHHTPVAQLFPGVEIVGNIVKGLVEQKIPREFDWESLQGKLCLVIFGLL FALVFSSIGIFGKLLIFFITTIVILTNTVILFVFYNNYVPPAFLLTITTLQTFVNFSYSYVIEKRQKRRISELFGQYVPK EYVKELIEHPEHHTMEGLNREMTVLFTDIRNFTTISETLGAGGVKQLLNSFFTPMTKIIFEHRGTIDKYVGDMIVAFWGA PIEDKEHANHAVLCSLSCFEHLPQINTHLLEHGLPQVNIGVGIATGPMNVGDMGSEFRRAYTVLGDTVNLASRLESLTKF YQVNILVSDKTRSHLDSILWRTVDKVAVKGRKSPLTIYQPLGIVEQASARLLQEQEKYETALAHYYNQDWLVAEIIFNEL KNVNPKIYLYQMYLERIAAFKKKRPSPDWDGVYVHRSK
Specific function: Unknown
COG id: COG2114
COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 guanylate cyclase domain [H]
Homologues:
Organism=Homo sapiens, GI222080083, Length=180, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561804, Length=185, Percent_Identity=32.972972972973, Blast_Score=71, Evalue=2e-12, Organism=Drosophila melanogaster, GI161078020, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001054 [H]
Pfam domain/function: PF00211 Guanylate_cyc [H]
EC number: =4.6.1.1 [H]
Molecular weight: Translated: 85626; Mature: 85626
Theoretical pI: Translated: 7.55; Mature: 7.55
Prosite motif: PS50125 GUANYLATE_CYCLASES_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFKSSKRIIFVNKLTLYFPQFLNHIKWTEFFLGLAVTLLVLLTLFFNVPPLNSLISQFEG CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC RVYDQIINFNWHSKPENLKVIIIDIDEKSLEQEGRWPWPRSKIAELLNKLQENGVVTVGF HHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEH DIVMSEAETNYALGLIEKLSQFSGKMTTDQKQLIATLNSVANQVDNDQTLVNALGKNNAI HEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE LGFFFHNSEGIRKGSLPPPLRDTDSNPLLASKLSVYQFTNFNGNLAAFTAAATSGGFVTN EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEEEEECCCCCEEEC LPDKDGVVRHALLLANYKNNLYPSLSLAIAMNYLLTDKVNLKKYNNELTGIELDGLQIPT CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCEECCC NRKGQILIPFWGGPGTLNYYSATDILNNQFNPDELAGSIALVGSSITLLSDLHHTPVAQL CCCCEEEEEEECCCCCCCEEEHHHHHCCCCCHHHHCCCHHEECCHHHHHHHHCCCCHHHH FPGVEIVGNIVKGLVEQKIPREFDWESLQGKLCLVIFGLLFALVFSSIGIFGKLLIFFIT CCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TIVILTNTVILFVFYNNYVPPAFLLTITTLQTFVNFSYSYVIEKRQKRRISELFGQYVPK HHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCH EYVKELIEHPEHHTMEGLNREMTVLFTDIRNFTTISETLGAGGVKQLLNSFFTPMTKIIF HHHHHHHHCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH EHRGTIDKYVGDMIVAFWGAPIEDKEHANHAVLCSLSCFEHLPQINTHLLEHGLPQVNIG HHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHCCCCEEEEE VGIATGPMNVGDMGSEFRRAYTVLGDTVNLASRLESLTKFYQVNILVSDKTRSHLDSILW EEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHH RTVDKVAVKGRKSPLTIYQPLGIVEQASARLLQEQEKYETALAHYYNQDWLVAEIIFNEL HHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH KNVNPKIYLYQMYLERIAAFKKKRPSPDWDGVYVHRSK HCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEECCC >Mature Secondary Structure MFKSSKRIIFVNKLTLYFPQFLNHIKWTEFFLGLAVTLLVLLTLFFNVPPLNSLISQFEG CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC RVYDQIINFNWHSKPENLKVIIIDIDEKSLEQEGRWPWPRSKIAELLNKLQENGVVTVGF HHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEH DIVMSEAETNYALGLIEKLSQFSGKMTTDQKQLIATLNSVANQVDNDQTLVNALGKNNAI HEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE LGFFFHNSEGIRKGSLPPPLRDTDSNPLLASKLSVYQFTNFNGNLAAFTAAATSGGFVTN EEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEEEEECCCCCEEEC LPDKDGVVRHALLLANYKNNLYPSLSLAIAMNYLLTDKVNLKKYNNELTGIELDGLQIPT CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCEECCC NRKGQILIPFWGGPGTLNYYSATDILNNQFNPDELAGSIALVGSSITLLSDLHHTPVAQL CCCCEEEEEEECCCCCCCEEEHHHHHCCCCCHHHHCCCHHEECCHHHHHHHHCCCCHHHH FPGVEIVGNIVKGLVEQKIPREFDWESLQGKLCLVIFGLLFALVFSSIGIFGKLLIFFIT CCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH TIVILTNTVILFVFYNNYVPPAFLLTITTLQTFVNFSYSYVIEKRQKRRISELFGQYVPK HHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCH EYVKELIEHPEHHTMEGLNREMTVLFTDIRNFTTISETLGAGGVKQLLNSFFTPMTKIIF HHHHHHHHCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH EHRGTIDKYVGDMIVAFWGAPIEDKEHANHAVLCSLSCFEHLPQINTHLLEHGLPQVNIG HHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHCCCCEEEEE VGIATGPMNVGDMGSEFRRAYTVLGDTVNLASRLESLTKFYQVNILVSDKTRSHLDSILW EEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHH RTVDKVAVKGRKSPLTIYQPLGIVEQASARLLQEQEKYETALAHYYNQDWLVAEIIFNEL HHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH KNVNPKIYLYQMYLERIAAFKKKRPSPDWDGVYVHRSK HCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9523018; 8418825 [H]