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The map label for this gene is pyrH [H]

Identifier: 54294595

GI number: 54294595

Start: 1864951

End: 1865694

Strand: Reverse

Name: pyrH [H]

Synonym: lpl1671

Alternate gene names: 54294595

Gene position: 1865694-1864951 (Counterclockwise)

Preceding gene: 54294596

Following gene: 54294594

Centisome position: 55.76

GC content: 42.47

Gene sequence:

>744_bases
ATGATGAATGAAAGTCAACCTAAATTAAAATACAAACGCATTCTGCTTAAATTTAGTGGTGAGGCGCTGATGGGGAAATC
TCAATTTGGGATTGATCCTTCAGTTCTTGACTCATTAGCTCGAGACATAGCAGAATTAATTCATATGGGTGTGGAAGTTG
GTTTGGTTTTAGGTGGAGGTAATCTGTTCAGAGGGAAAGCGCTCTCTCAGGCGGGTGTAGGACGAGTGACAGGAGACCAT
ATGGGGATGCTGGCCACTGTTATGAATGCTTTGGCACTCCGTGATGCTTTGGAGCGAATTGATCTGCCTGCTCGTATTAT
GTCAGCTATTCCAATGCTTGGGGTAGTTGACCCATACCATAGACGAAAAGCTATCACTCACTTGCGCAATGGTCAGGTGG
TGATTTTTGCAGCTGGAACAGGAAATCCCTTTTTTACAACAGATACTGCTGCTTGTTTGAGGGCAATTGAGATAGGCGCA
GATATTGTTTTAAAAGCAACAAAGGTGGATGGAGTTTATTCTGCTGACCCACTTAAAAACCCTGATGCAAAGCGTTATGA
TTATTTGACTTACAAAGAAGTTTTAACCAAAGGTTTGGAAGTGATGGATTCCACTGCAATTTGTTTGTGCCAAGATCAGG
GAATGCCTTTACAGGTGTTTGATATGGCGGCCCCTAAAGCATTAAAACGAATTGTAACTGGAGAACGAGTAGGAACTATA
GTCGGAGCTAATCATGATCAATGA

Upstream 100 bases:

>100_bases
AAAATGCTGAAGTAATATCCTTTGTTCGTTATGAAGTAGGGGAAGGAATAGAGAAAAAAGAGGACAATTTTGTTGAAGAA
GTGATGGCTCAGGTTCGTAC

Downstream 100 bases:

>100_bases
GATTAAGCAAGATTCAGAAAAACGCATGAAAAAGACTATTGAGGCTTTGCATACGGATATGTCAAAAATCCGTACCGGCA
GGGCAAATGCGAGTCTATTA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MMNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDH
MGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGA
DIVLKATKVDGVYSADPLKNPDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTI
VGANHDQ

Sequences:

>Translated_247_residues
MMNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDH
MGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGA
DIVLKATKVDGVYSADPLKNPDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTI
VGANHDQ
>Mature_247_residues
MMNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGGNLFRGKALSQAGVGRVTGDH
MGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYHRRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGA
DIVLKATKVDGVYSADPLKNPDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTI
VGANHDQ

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=237, Percent_Identity=61.1814345991561, Blast_Score=301, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26671; Mature: 26671

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGG
CCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEECC
NLFRGKALSQAGVGRVTGDHMGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYH
CEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
RRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGADIVLKATKVDGVYSADPLKN
HHHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
PDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTI
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHEEE
VGANHDQ
ECCCCCC
>Mature Secondary Structure
MMNESQPKLKYKRILLKFSGEALMGKSQFGIDPSVLDSLARDIAELIHMGVEVGLVLGGG
CCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEECC
NLFRGKALSQAGVGRVTGDHMGMLATVMNALALRDALERIDLPARIMSAIPMLGVVDPYH
CEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
RRKAITHLRNGQVVIFAAGTGNPFFTTDTAACLRAIEIGADIVLKATKVDGVYSADPLKN
HHHHHHHHCCCCEEEEEECCCCCCEECHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
PDAKRYDYLTYKEVLTKGLEVMDSTAICLCQDQGMPLQVFDMAAPKALKRIVTGERVGTI
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHEEE
VGANHDQ
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA