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The map label for this gene is cpg2 [H]

Identifier: 54294588

GI number: 54294588

Start: 1857737

End: 1858960

Strand: Direct

Name: cpg2 [H]

Synonym: lpl1664

Alternate gene names: 54294588

Gene position: 1857737-1858960 (Clockwise)

Preceding gene: 54294585

Following gene: 54294589

Centisome position: 55.53

GC content: 42.4

Gene sequence:

>1224_bases
ATGGTTAAATTATATAAGGAAATAATCAATTCAATAGATAATCATCAGACAACGATGGTGGAGCAACTCCATCAATTTTG
TGAAATCAATTCTGGAACAACTAATTTGACAGGATTAGCCGTCATGGCTGAGACATTGTGCTCAGCATTCAAACCAATCG
CTGATACCACAGAATTAATAAAATTACCGCCTTTGTCTGTAATTGACATGACCGGAAGCACGGTTACGCAATCCTGTGGG
GATGCATTGTTCATTAGCAAACGCCCCCACTTAAAACGCCGAATTCTGCTAAGCGGTCATATGGATACGGTTTATTCCGC
CAGCAACCCTTTTCAAAAATTAAGCTACCTCAATGCTAATCAAATCAATGGTCCTGGTGTTGCAGATATGAAAGGGGGAC
TAATCGTCATCTTGCATGCATTAGAAGCCTTTGAAAACACCAAATTTGCGGAAGAAATGGGTTGGGATGTGTTAATTAAT
TCAGATGAGGAAATTGGTTCGCCTGCATCAGGTTCATTATTCAAAGAATTGGCACATCGCTATCAAGCCGCTTTGGTTTA
TGAACCAGCAATGACACCTAAAGGTACTTTGGCAAAAAACCGCAAAGGCAGTGGAAAACTAACGCTGGTAGCAACAGGAA
GAGCTGCCCATGCAGGCCGGGCATTTGATGAAGGAAGAAACGCCATATGCTATCTTGCTGAAGCAGTTACGGCTGTTCAT
GCCTTAAATGGGCAAAGAAATGGAGTAACAATCAATGTAGGTAAAATCGCTGGTGGAGAAGCACTGAATGTTGTTCCTGA
TAAGGCAGTAGCACAACTGGATATCCGAATCAGTCTGCCAGAAGATGAAATTTGGGTAAGGAATGAATTGAATAAAATTA
TCAGACAGCTAGAGCGACCTGATTATTCTCTAAGTGTGCATGGCACTTTTGGACGGCCTGTGAAGCTTATCTGCGCAGGG
ACAGAACGACTTTTTCATCGGATTCAAAAAATTGGAGAGGCGCTTGGCTTAACTATTGACTGGAAAGACAGTGGAGGTTG
TTGCGACGGTAATAATTTGGCTCACTATGGCTTGCCTGTTCTGGATACTCTAGGTGTTCGGGGAGGCAATATACACAGTT
CAGATGAATATATATTGCTTGATAGCTTATCAGAGCGCGCTGCACTTAGCGCGCTTCTTCTGATAGATTTGGCACAGGGT
GGTTTAGAGGATCTAATAAAATGA

Upstream 100 bases:

>100_bases
GCTCAGACAAGAATGAGAGTTCTATATGACGACTATACTGAATTGACGCCAATACTCAAATTACGCTATTGTTGGGGATT
TAGTGTAAGACTAAAGAGCC

Downstream 100 bases:

>100_bases
TGTTATTTCGTAGTGCCCGCGACTCTGACTTGGATGCGATCCATCAACTGGCAGAAATCAGTGGTGTTGGGATGACAACG
CTCCCTAAAGATAAAGAATT

Product: hypothetical protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MVKLYKEIINSIDNHQTTMVEQLHQFCEINSGTTNLTGLAVMAETLCSAFKPIADTTELIKLPPLSVIDMTGSTVTQSCG
DALFISKRPHLKRRILLSGHMDTVYSASNPFQKLSYLNANQINGPGVADMKGGLIVILHALEAFENTKFAEEMGWDVLIN
SDEEIGSPASGSLFKELAHRYQAALVYEPAMTPKGTLAKNRKGSGKLTLVATGRAAHAGRAFDEGRNAICYLAEAVTAVH
ALNGQRNGVTINVGKIAGGEALNVVPDKAVAQLDIRISLPEDEIWVRNELNKIIRQLERPDYSLSVHGTFGRPVKLICAG
TERLFHRIQKIGEALGLTIDWKDSGGCCDGNNLAHYGLPVLDTLGVRGGNIHSSDEYILLDSLSERAALSALLLIDLAQG
GLEDLIK

Sequences:

>Translated_407_residues
MVKLYKEIINSIDNHQTTMVEQLHQFCEINSGTTNLTGLAVMAETLCSAFKPIADTTELIKLPPLSVIDMTGSTVTQSCG
DALFISKRPHLKRRILLSGHMDTVYSASNPFQKLSYLNANQINGPGVADMKGGLIVILHALEAFENTKFAEEMGWDVLIN
SDEEIGSPASGSLFKELAHRYQAALVYEPAMTPKGTLAKNRKGSGKLTLVATGRAAHAGRAFDEGRNAICYLAEAVTAVH
ALNGQRNGVTINVGKIAGGEALNVVPDKAVAQLDIRISLPEDEIWVRNELNKIIRQLERPDYSLSVHGTFGRPVKLICAG
TERLFHRIQKIGEALGLTIDWKDSGGCCDGNNLAHYGLPVLDTLGVRGGNIHSSDEYILLDSLSERAALSALLLIDLAQG
GLEDLIK
>Mature_407_residues
MVKLYKEIINSIDNHQTTMVEQLHQFCEINSGTTNLTGLAVMAETLCSAFKPIADTTELIKLPPLSVIDMTGSTVTQSCG
DALFISKRPHLKRRILLSGHMDTVYSASNPFQKLSYLNANQINGPGVADMKGGLIVILHALEAFENTKFAEEMGWDVLIN
SDEEIGSPASGSLFKELAHRYQAALVYEPAMTPKGTLAKNRKGSGKLTLVATGRAAHAGRAFDEGRNAICYLAEAVTAVH
ALNGQRNGVTINVGKIAGGEALNVVPDKAVAQLDIRISLPEDEIWVRNELNKIIRQLERPDYSLSVHGTFGRPVKLICAG
TERLFHRIQKIGEALGLTIDWKDSGGCCDGNNLAHYGLPVLDTLGVRGGNIHSSDEYILLDSLSERAALSALLLIDLAQG
GLEDLIK

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 44023; Mature: 44023

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLYKEIINSIDNHQTTMVEQLHQFCEINSGTTNLTGLAVMAETLCSAFKPIADTTELI
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
KLPPLSVIDMTGSTVTQSCGDALFISKRPHLKRRILLSGHMDTVYSASNPFQKLSYLNAN
CCCCCEEEECCCCHHHHHCCCEEEECCCCCHHHEEEEECCCHHHHCCCCCHHHHHHCCCC
QINGPGVADMKGGLIVILHALEAFENTKFAEEMGWDVLINSDEEIGSPASGSLFKELAHR
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHH
YQAALVYEPAMTPKGTLAKNRKGSGKLTLVATGRAAHAGRAFDEGRNAICYLAEAVTAVH
HHEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHH
ALNGQRNGVTINVGKIAGGEALNVVPDKAVAQLDIRISLPEDEIWVRNELNKIIRQLERP
HHCCCCCCEEEEECCCCCCCEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
DYSLSVHGTFGRPVKLICAGTERLFHRIQKIGEALGLTIDWKDSGGCCDGNNLAHYGLPV
CCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCH
LDTLGVRGGNIHSSDEYILLDSLSERAALSALLLIDLAQGGLEDLIK
HHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MVKLYKEIINSIDNHQTTMVEQLHQFCEINSGTTNLTGLAVMAETLCSAFKPIADTTELI
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
KLPPLSVIDMTGSTVTQSCGDALFISKRPHLKRRILLSGHMDTVYSASNPFQKLSYLNAN
CCCCCEEEECCCCHHHHHCCCEEEECCCCCHHHEEEEECCCHHHHCCCCCHHHHHHCCCC
QINGPGVADMKGGLIVILHALEAFENTKFAEEMGWDVLINSDEEIGSPASGSLFKELAHR
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHH
YQAALVYEPAMTPKGTLAKNRKGSGKLTLVATGRAAHAGRAFDEGRNAICYLAEAVTAVH
HHEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHH
ALNGQRNGVTINVGKIAGGEALNVVPDKAVAQLDIRISLPEDEIWVRNELNKIIRQLERP
HHCCCCCCEEEEECCCCCCCEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
DYSLSVHGTFGRPVKLICAGTERLFHRIQKIGEALGLTIDWKDSGGCCDGNNLAHYGLPV
CCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCH
LDTLGVRGGNIHSSDEYILLDSLSERAALSALLLIDLAQGGLEDLIK
HHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]