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The map label for this gene is putA [H]

Identifier: 54294579

GI number: 54294579

Start: 1845370

End: 1848522

Strand: Reverse

Name: putA [H]

Synonym: lpl1655

Alternate gene names: 54294579

Gene position: 1848522-1845370 (Counterclockwise)

Preceding gene: 54294582

Following gene: 54294575

Centisome position: 55.25

GC content: 40.79

Gene sequence:

>3153_bases
ATGCTGGAAAAGCAGTCCATTCATTTACCGGAAGGATTAAGAGCTGCTATTAATAAAGCTTATCGCATGGATGAGCTTTC
TTTAATTACAGAGCTTAGTGAACAGGCGGCACTTGATCCTCAGCAAATGATGGCAATTAAAACCAGTGCTACAAAATTGG
TTCAATCAGTTCGTAGTGAGAGAAAGAAAAGCACCGGAATAGATTCTTTTTTAACGGAGTATGCCTTATCAAGTGATGAG
GGAATTGCCTTAATGTGTCTGGCAGAAGCTTTATTACGCGTTCCTGATAATGCAACTATAGATAACTTGATTAAAGATAA
ATTAGCTGGCGGTGATTGGGGGGCACATCGTGGACAGAGTGAATCATTTTTTGTAAATGCTACTACTTGGGCTTTAATGC
TAACTGGTAAAGTTTTAACTCCTGAAAAAGCTGAAAATACATTAACCAAAGCTTTACTAAAATTGGTTAATCGAAGTAGT
GAGGCTGTTGTTAGAAAAGCAGTGGATAAAGCCATGCGAATTATGAGCAAACAATTTGTGATGGGACGCACCATTAATGA
AGCGTTAGCTCGAGCGAAAAAAAAGGAAGACAGGGGATACAGATATTCTTACGATATGCTTGGTGAAGCTGCCTTAACAT
CTGCTGATGCTGCAAGATATTTTGAAGCCTACAAGGAAGCAATCATTTCAATTGGAGAGAAAGCTGATAAACATTCAGAT
GTATATAGACGCCCTGGTATTTCCATCAAACTTTCTGCCTTACATCCACGATATAGCGAGTTTCAGTATGAGCGTGTCAT
TGAAGAATTACCCCCCAAATTATTAGCCTTGTCTCGTTTAGCAAAAGATTATGACATTGCTTTGACAATTGACGCCGAGG
AGTCAGAGCGTTTAGATCTTTCACTTGATGTGATAGAGAAAGTGTTTACTGATGAGAGTTTACAGGGATGGAATGGGTTC
GGTTTGGCCGTTCAATCCTATCAAAAAAGAGCTTTTTATGTCTTGGATTGGGTTGCTGCTTTAGCAAGAAGTAAGCAGCG
GCGTATTATGGTCAGATTGATTAAAGGAGCCTATTGGGATAGTGAAATCAAAAAAACGCAAATGCAAGGCTTTTCTGAAT
ACCCGGTTTTTACCCGTAAAGTTTTTACTGATGTCTCATTTCAGGCTTGCGCAAAAAAAATCCTGACTATGACCGATGCC
ATTTATCCACAATTTGCCACACATAATGCTTATTCTGTAGCAATGATTCTTAATTTGGTAGGAGGTTATAGAGATTTTGA
ATTTCAATGTCTTCATGGTATGGGTAATGAACTTTATGAACAGATTGTTCCAGCAAATTGTTATGGTATTCCATGCCGTA
TTTATGCACCAGTTGGTAGCCATGAGGATTTACTACCGTATTTAGTTCGACGATTACTGGAAAATGGCGCAAACTCATCT
TTTGTCAATCGCATAGTTGATGATAAGGCACCTATTAGCGAGTTAGTGGAGGATCCGGTAACTAAATCAAAATCGTTACT
TGATAAAATAAATAAAAATATACCATTGCCAGAGGATATCTTTTTACCCGTACGAAAAAACTCTAAAGGCTTTGACTTTA
CAAATCGACTTGAACGCGCATTATTGCAGCAGGAGCTGGAAAAAATTGAATCAAAAGAATGGCAGGCAAGTCCTATGATT
GCAGGTCGAAAATTATCCAGGGACTTACTGCAAACAGTTATGTCCCCACAGCAGCCGGCATATGCTATTGGCTCAGTGCA
GCAAGCCACACTTGATGATGTAGAGGTGGCATTAAATCAGGCAAAATTGGCTTTTGAATTGTGGAGCAAGAAACCGGTAG
AAGAACGTGCTTCCTGTCTAAATCGATTTGCAGATTTATTACAGGCCAATATGGCAGAGCTCATGGTATTGACTTGTCGG
GAAGCTGGTAAAACCTGGAGTGATGGCATTGCTGAAGTAAGAGAGGCTATTGATTTTTGTCGATACTATGCCAAGAAAGC
TCAAGAGCTTATGAGTAGCCCTCAACACTTTAATGGATACACTGGGGAACTAAATGAATTGAGTTTGCATCCTCGCGGGA
CAATATTGTGTATTAGTCCCTGGAATTTTCCATTGGCTATATTTACGGGACAAGTCGTAGCTGGGCTGGTTACAGGCAAT
TGTGTTATTGCGAAACCGGCAGAACAAACGCCACTAATTGCAGCCTATGCTGTGAAGTTAATGCATCAGGCTGGTATCCC
TGAAGGAGTAATTCAATTAATTCCAGGCGCTGGCGAGACTATTGGCGCTGCTTTGGTCGCAGATAAACGAATTAAAGCCG
TATTATTTACAGGCTCGACTGACACGGCGAATTTGATTAACCGGACGCTAGCTACTAGAGGCGGTGAAATTATTCCTCTA
ATTGCTGAAACGGGTGGTCAAAATGCAATGATTGTCGATTCTTCAGCGTTATTGGAGCAAGTGGTTGTTGATGCTGTCAC
TTCTGCCTTTGGCAGCGCGGGGCAGCGATGCTCGGCACTTAGAGTATTGTATGTGCAAGAGGAAGTGTATCCAAGAACTG
TAGAGCTATTAAAAGGTGCCATGGCTGAGCTAGTCGTAGGGGATCCTCAATGGTTATCAACCGATGTTGGCCCTGTTATA
GACAAGGAAGCATTATCTATATTGAAAAATCATGTCGAAAACATGAGAAAACATCATGAAATATTATATCAATGCACTGT
TGACGATGAAGCTTTATCAGGATATTTCATGCCGCCAACAGCTATTGCAATTGATAGTATCAGCGCTTTGGAAAAAGAAG
TATTTGGGCCAATTTTGCATGTGATTCAGTTTAAGAGAAAAGATCTGGATAAGGTAATTAATCAAATCAATCAAACTGGC
TATGGTTTAACACTGGGAATACACAGCCGAATTAATGAAACAGTTGACTACATTAGGCAAAGAGTTCACGCAGGGAACTG
TTATGTTAATCGTAATATGATTGGCGCAGTAGTAGGCCTGCAGCCTTTTGGTGGTGAAGGGTTATCTGGCACAGGACCCA
AGGCCGGAGGCCCTAACTATTTGATTCGACTTTGCCATGAGCGTACCTATACAGTTGATACAACTGCTGCAGGAGGTAAT
GCCAGTTTAATGTCTATTCCGGAAGAAGGTTAG

Upstream 100 bases:

>100_bases
GATTTTTTCATTGTTATAATAATGAATTTAATTTTTGTCTTATATGGTAAAAATTTAATAACTATTTTTTTCAATTACCA
CTTTAGTCTTGGAGAACATT

Downstream 100 bases:

>100_bases
CAGTATTAGAAATTCACTTAAGAGAATAATACAATCTTAAGTGAATTTATTACAGGAGATATGCTCCTGTCTGCAACGGC
AATATTTGGTCGATCTTGTA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1050; Mature: 1050

Protein sequence:

>1050_residues
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSERKKSTGIDSFLTEYALSSDE
GIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQSESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSS
EAVVRKAVDKAMRIMSKQFVMGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
VYRRPGISIKLSALHPRYSEFQYERVIEELPPKLLALSRLAKDYDIALTIDAEESERLDLSLDVIEKVFTDESLQGWNGF
GLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWDSEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDA
IYPQFATHNAYSVAMILNLVGGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
FVNRIVDDKAPISELVEDPVTKSKSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERALLQQELEKIESKEWQASPMI
AGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQAKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCR
EAGKTWSDGIAEVREAIDFCRYYAKKAQELMSSPQHFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGSTDTANLINRTLATRGGEIIPL
IAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSALRVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVI
DKEALSILKNHVENMRKHHEILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTG
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNYLIRLCHERTYTVDTTAAGGN
ASLMSIPEEG

Sequences:

>Translated_1050_residues
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSERKKSTGIDSFLTEYALSSDE
GIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQSESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSS
EAVVRKAVDKAMRIMSKQFVMGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
VYRRPGISIKLSALHPRYSEFQYERVIEELPPKLLALSRLAKDYDIALTIDAEESERLDLSLDVIEKVFTDESLQGWNGF
GLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWDSEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDA
IYPQFATHNAYSVAMILNLVGGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
FVNRIVDDKAPISELVEDPVTKSKSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERALLQQELEKIESKEWQASPMI
AGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQAKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCR
EAGKTWSDGIAEVREAIDFCRYYAKKAQELMSSPQHFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGSTDTANLINRTLATRGGEIIPL
IAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSALRVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVI
DKEALSILKNHVENMRKHHEILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTG
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNYLIRLCHERTYTVDTTAAGGN
ASLMSIPEEG
>Mature_1050_residues
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSERKKSTGIDSFLTEYALSSDE
GIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQSESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSS
EAVVRKAVDKAMRIMSKQFVMGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
VYRRPGISIKLSALHPRYSEFQYERVIEELPPKLLALSRLAKDYDIALTIDAEESERLDLSLDVIEKVFTDESLQGWNGF
GLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWDSEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDA
IYPQFATHNAYSVAMILNLVGGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
FVNRIVDDKAPISELVEDPVTKSKSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERALLQQELEKIESKEWQASPMI
AGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQAKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCR
EAGKTWSDGIAEVREAIDFCRYYAKKAQELMSSPQHFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGSTDTANLINRTLATRGGEIIPL
IAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSALRVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVI
DKEALSILKNHVENMRKHHEILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTG
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNYLIRLCHERTYTVDTTAAGGN
ASLMSIPEEG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=446, Percent_Identity=30.9417040358744, Blast_Score=200, Evalue=6e-51,
Organism=Homo sapiens, GI21361176, Length=475, Percent_Identity=30.7368421052632, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI25777730, Length=446, Percent_Identity=32.0627802690583, Blast_Score=197, Evalue=6e-50,
Organism=Homo sapiens, GI25777724, Length=440, Percent_Identity=31.3636363636364, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI153266822, Length=446, Percent_Identity=30.4932735426009, Blast_Score=193, Evalue=9e-49,
Organism=Homo sapiens, GI25777736, Length=508, Percent_Identity=31.1023622047244, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI25777734, Length=508, Percent_Identity=31.1023622047244, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI238859541, Length=491, Percent_Identity=31.1608961303462, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI12007648, Length=442, Percent_Identity=28.9592760180996, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI25777728, Length=408, Percent_Identity=31.1274509803922, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI238814322, Length=414, Percent_Identity=29.4685990338164, Blast_Score=176, Evalue=1e-43,
Organism=Homo sapiens, GI21614513, Length=415, Percent_Identity=29.1566265060241, Blast_Score=174, Evalue=4e-43,
Organism=Homo sapiens, GI188035924, Length=469, Percent_Identity=28.7846481876333, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI310128093, Length=443, Percent_Identity=29.1196388261851, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI310128103, Length=443, Percent_Identity=29.1196388261851, Blast_Score=165, Evalue=3e-40,
Organism=Homo sapiens, GI115387104, Length=435, Percent_Identity=27.1264367816092, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI25952152, Length=436, Percent_Identity=28.2110091743119, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI25777726, Length=443, Percent_Identity=27.9909706546275, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI310128091, Length=443, Percent_Identity=27.765237020316, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI4507229, Length=474, Percent_Identity=27.4261603375527, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI11095441, Length=418, Percent_Identity=27.2727272727273, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI25777721, Length=487, Percent_Identity=26.4887063655031, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI310128087, Length=265, Percent_Identity=29.811320754717, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI301500698, Length=442, Percent_Identity=24.8868778280543, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI310128089, Length=335, Percent_Identity=29.5522388059701, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI206597441, Length=446, Percent_Identity=23.542600896861, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI206597439, Length=446, Percent_Identity=23.542600896861, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI22907049, Length=446, Percent_Identity=23.542600896861, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI4502043, Length=426, Percent_Identity=23.2394366197183, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI238814371, Length=426, Percent_Identity=23.2394366197183, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI71773324, Length=323, Percent_Identity=25.077399380805, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=29.0322580645161, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI73695881, Length=340, Percent_Identity=25.2941176470588, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI73695879, Length=340, Percent_Identity=25.2941176470588, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310128097, Length=257, Percent_Identity=30.7392996108949, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128099, Length=218, Percent_Identity=27.5229357798165, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI73466520, Length=442, Percent_Identity=23.3031674208145, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI4557303, Length=442, Percent_Identity=23.3031674208145, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI310128101, Length=215, Percent_Identity=26.9767441860465, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1787250, Length=1044, Percent_Identity=51.6283524904215, Blast_Score=1047, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=448, Percent_Identity=29.6875, Blast_Score=178, Evalue=2e-45,
Organism=Escherichia coli, GI1787715, Length=411, Percent_Identity=30.1703163017032, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI87081896, Length=466, Percent_Identity=28.5407725321888, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1788042, Length=432, Percent_Identity=30.0925925925926, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI1787684, Length=465, Percent_Identity=29.247311827957, Blast_Score=156, Evalue=5e-39,
Organism=Escherichia coli, GI87082295, Length=441, Percent_Identity=29.7052154195011, Blast_Score=154, Evalue=4e-38,
Organism=Escherichia coli, GI1787558, Length=434, Percent_Identity=29.7235023041475, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI1786504, Length=455, Percent_Identity=26.5934065934066, Blast_Score=135, Evalue=2e-32,
Organism=Escherichia coli, GI87081926, Length=404, Percent_Identity=26.4851485148515, Blast_Score=131, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17534447, Length=521, Percent_Identity=30.5182341650672, Blast_Score=200, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI115534176, Length=452, Percent_Identity=32.5221238938053, Blast_Score=186, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17562198, Length=442, Percent_Identity=30.5429864253394, Blast_Score=179, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI133930964, Length=437, Percent_Identity=30.6636155606407, Blast_Score=178, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI115532534, Length=392, Percent_Identity=31.6326530612245, Blast_Score=177, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25144435, Length=443, Percent_Identity=29.7968397291196, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=30.3921568627451, Blast_Score=163, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=458, Percent_Identity=28.3842794759825, Blast_Score=163, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=458, Percent_Identity=28.3842794759825, Blast_Score=162, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI32564151, Length=467, Percent_Identity=28.4796573875803, Blast_Score=156, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17551164, Length=437, Percent_Identity=27.6887871853547, Blast_Score=153, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71995606, Length=439, Percent_Identity=26.1958997722096, Blast_Score=139, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI71995613, Length=396, Percent_Identity=26.010101010101, Blast_Score=133, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=441, Percent_Identity=26.530612244898, Blast_Score=132, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=417, Percent_Identity=26.378896882494, Blast_Score=129, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71990744, Length=368, Percent_Identity=28.804347826087, Blast_Score=122, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI25146391, Length=415, Percent_Identity=23.6144578313253, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=415, Percent_Identity=23.6144578313253, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=415, Percent_Identity=23.6144578313253, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=419, Percent_Identity=23.3890214797136, Blast_Score=95, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=445, Percent_Identity=33.4831460674157, Blast_Score=194, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6324950, Length=434, Percent_Identity=32.258064516129, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6325196, Length=441, Percent_Identity=30.3854875283447, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6321826, Length=519, Percent_Identity=29.4797687861272, Blast_Score=184, Evalue=6e-47,
Organism=Saccharomyces cerevisiae, GI6323821, Length=462, Percent_Identity=30.952380952381, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323822, Length=447, Percent_Identity=29.7539149888143, Blast_Score=181, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6319478, Length=445, Percent_Identity=26.5168539325843, Blast_Score=142, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=507, Percent_Identity=24.2603550295858, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=26.3803680981595, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129399, Length=445, Percent_Identity=32.3595505617978, Blast_Score=207, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24668425, Length=532, Percent_Identity=28.7593984962406, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24668417, Length=532, Percent_Identity=28.7593984962406, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24668413, Length=532, Percent_Identity=28.7593984962406, Blast_Score=196, Evalue=6e-50,
Organism=Drosophila melanogaster, GI281362580, Length=437, Percent_Identity=30.4347826086957, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472918, Length=437, Percent_Identity=30.4347826086957, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472926, Length=437, Percent_Identity=30.4347826086957, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI62472936, Length=437, Percent_Identity=30.4347826086957, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21356737, Length=437, Percent_Identity=30.4347826086957, Blast_Score=177, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=29.9107142857143, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24666674, Length=466, Percent_Identity=28.9699570815451, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24585660, Length=440, Percent_Identity=27.5, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28574525, Length=506, Percent_Identity=26.6798418972332, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28571802, Length=502, Percent_Identity=25.8964143426295, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571800, Length=502, Percent_Identity=25.8964143426295, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571806, Length=502, Percent_Identity=25.8964143426295, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571798, Length=502, Percent_Identity=25.8964143426295, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571796, Length=502, Percent_Identity=25.8964143426295, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571794, Length=502, Percent_Identity=25.8964143426295, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24638878, Length=415, Percent_Identity=26.2650602409639, Blast_Score=110, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24638876, Length=415, Percent_Identity=26.2650602409639, Blast_Score=110, Evalue=6e-24,
Organism=Drosophila melanogaster, GI281360303, Length=439, Percent_Identity=24.373576309795, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45552499, Length=434, Percent_Identity=23.5023041474654, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360301, Length=439, Percent_Identity=24.373576309795, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281360299, Length=434, Percent_Identity=23.5023041474654, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281360297, Length=434, Percent_Identity=23.5023041474654, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281360295, Length=434, Percent_Identity=23.5023041474654, Blast_Score=90, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586250, Length=434, Percent_Identity=23.5023041474654, Blast_Score=90, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116211; Mature: 116211

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RKKSTGIDSFLTEYALSSDEGIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQS
HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
ESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSSEAVVRKAVDKAMRIMSKQFV
CCEEEEHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
HCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VYRRPGISIKLSALHPRYSEFQYERVIEELPPKLLALSRLAKDYDIALTIDAEESERLDL
HHHCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCCC
SLDVIEKVFTDESLQGWNGFGLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDAIYPQFATHNAYSVAMILNLV
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHH
GGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
CCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHH
FVNRIVDDKAPISELVEDPVTKSKSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERA
HHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHH
LLQQELEKIESKEWQASPMIAGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQ
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHH
AKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCREAGKTWSDGIAEVREAIDFC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RYYAKKAQELMSSPQHFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
HHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGST
EEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCC
DTANLINRTLATRGGEIIPLIAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSAL
CHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHH
RVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVIDKEALSILKNHVENMRKHHE
EEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTG
HHEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNY
CEEEEEHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEECCCCCCCCCCCCCCCCCCCHH
LIRLCHERTYTVDTTAAGGNASLMSIPEEG
HHHHHHCCCEEEEECCCCCCCEEECCCCCC
>Mature Secondary Structure
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RKKSTGIDSFLTEYALSSDEGIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQS
HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
ESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSSEAVVRKAVDKAMRIMSKQFV
CCEEEEHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
HCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VYRRPGISIKLSALHPRYSEFQYERVIEELPPKLLALSRLAKDYDIALTIDAEESERLDL
HHHCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCCCC
SLDVIEKVFTDESLQGWNGFGLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDAIYPQFATHNAYSVAMILNLV
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHH
GGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
CCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHH
FVNRIVDDKAPISELVEDPVTKSKSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERA
HHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHH
LLQQELEKIESKEWQASPMIAGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQ
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHH
AKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCREAGKTWSDGIAEVREAIDFC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RYYAKKAQELMSSPQHFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
HHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGST
EEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCC
DTANLINRTLATRGGEIIPLIAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSAL
CHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHH
RVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVIDKEALSILKNHVENMRKHHE
EEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTG
HHEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNY
CEEEEEHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEECCCCCCCCCCCCCCCCCCCHH
LIRLCHERTYTVDTTAAGGNASLMSIPEEG
HHHHHHCCCEEEEECCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]