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The map label for this gene is relE [H]

Identifier: 54294513

GI number: 54294513

Start: 1765591

End: 1765848

Strand: Direct

Name: relE [H]

Synonym: lpl1588

Alternate gene names: 54294513

Gene position: 1765591-1765848 (Clockwise)

Preceding gene: 54294512

Following gene: 54294514

Centisome position: 52.77

GC content: 37.98

Gene sequence:

>258_bases
ATGAGCTTTGAGCTTGGATTTTTAGATGAGGCATTAAAAGAATGGAGAAAGCTTGACAATAATACACGCGATCAATTTAA
GAAAAAACTTGCAGAGCGTCTTATCAATCCTCGTGTACCTGCCTCGAAATTAAGTGGTCAAAAAGATCGGTATAAAATTA
AACTTCGGAACATTGGTTACCGGTTGGTCTACGAAGTTCGAGATGCTGAACTAATCGTTGGGATGTGTTTCCCGACTACT
CAAAAATTGAACAGATAA

Upstream 100 bases:

>100_bases
GCAAAGCTTTATGAAAAATTCATGAATAAACTTGAAGATATAGAGCTTAATAGCATTGCTGATTCAAGAAAAAATAATCC
AGTTATTAAGGTAAAATTGG

Downstream 100 bases:

>100_bases
ATGATACAGCTCCATTATTTAAAGTTGAAAACGGCGTTTTGCTTAAACGAGTTAATAATAAGGATCGCTATGATCATCAT
TGGACAAAATACTGGAGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MSFELGFLDEALKEWRKLDNNTRDQFKKKLAERLINPRVPASKLSGQKDRYKIKLRNIGYRLVYEVRDAELIVGMCFPTT
QKLNR

Sequences:

>Translated_85_residues
MSFELGFLDEALKEWRKLDNNTRDQFKKKLAERLINPRVPASKLSGQKDRYKIKLRNIGYRLVYEVRDAELIVGMCFPTT
QKLNR
>Mature_84_residues
SFELGFLDEALKEWRKLDNNTRDQFKKKLAERLINPRVPASKLSGQKDRYKIKLRNIGYRLVYEVRDAELIVGMCFPTTQ
KLNR

Specific function: Inhibits translation during amino acid starvation. Acts by cleaving mRNA with high codon specificity in the ribosomal A site. UGA is cleaved with fast rate while UAA and UGA are cleaved with intermediate and slow rate, respectively. mRNA cleavage can also

COG id: COG2026

COG function: function code JD; Cytotoxic translational repressor of toxin-antitoxin stability system

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787846, Length=73, Percent_Identity=56.1643835616438, Blast_Score=81, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007712
- InterPro:   IPR012753 [H]

Pfam domain/function: PF05016 Plasmid_stabil [H]

EC number: NA

Molecular weight: Translated: 10103; Mature: 9972

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFELGFLDEALKEWRKLDNNTRDQFKKKLAERLINPRVPASKLSGQKDRYKIKLRNIGY
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCE
RLVYEVRDAELIVGMCFPTTQKLNR
EEEEEECCCEEEEEECCCCHHCCCC
>Mature Secondary Structure 
SFELGFLDEALKEWRKLDNNTRDQFKKKLAERLINPRVPASKLSGQKDRYKIKLRNIGY
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCE
RLVYEVRDAELIVGMCFPTTQKLNR
EEEEEECCCEEEEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2990907; 9097039; 9278503; 9767574; 12526800 [H]