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The map label for this gene is cyaB [H]

Identifier: 54294469

GI number: 54294469

Start: 1712122

End: 1713417

Strand: Reverse

Name: cyaB [H]

Synonym: lpl1538

Alternate gene names: 54294469

Gene position: 1713417-1712122 (Counterclockwise)

Preceding gene: 54294470

Following gene: 54294468

Centisome position: 51.21

GC content: 37.04

Gene sequence:

>1296_bases
ATGAGTGCCTTGTACTATAATTTTAATAACCACTACGCCTCTCATTTTGTTTATTCACCTGAGAAAATTATGAAGAAACC
TTTGGATAATACTGAGCAGAATCGCATTGCTGCATTATACGAATTAAAAATTCTGGATACACCAGCAGACGAAAGATTTG
ATCGAATTATTCGGCTCACTTCGGGTTACTTATCGGTTCCTATTGCTTTTATTTCCTTTATTGACTCTAAACATCAATGG
TTCAAATCCAGCTGTGGCATAGGGCTTAACAAAATATCCCGGAATGATTCATTTTGCCATTACACTATTCAGCAAAATAA
ACCGATGATTATTTCAGACGCCTTGTTGGATGAGCGATTTTGTAATAATCCCTATGTGACTAACTCGCCAAATATTCGTT
TTTATGCAGGATTCCCATTATCTACAGTTGATGGTTTTAACATAGGAACACTATGCGCAATAGATAAAAAACCACGTAAT
TTAGACGAGACTGAAATTCAAATTTTAAAAGATTTGGCAACTTTGGCAGAAGATCAAGTCAATCTGCTTGATATTTCGCT
TCTTGAGAGAGCTGTACGAGAAAAAAACATTTCTCTGACAAAAGCTAAGAAAGAACTTGAAATGCGTAATAATTTTATTC
GTAAAGTATTTGGTAGTTTTATGTCTGACGAGATTGTTGCAGCACTTCTTGAATCAAAATCAGAGTTAAAATTAGGAGGT
GAGGAGCGCAAAATTACAATTTTGTTTAGCGACTTAAGAAATTTTACTACTCTGTCGGAGCATTTTCCTGCGGATAAAAT
TGTCGCCGCACTTAACAATCATTATGGAAAAATGGTTGATGTCATAGAAAAATACAATGGTACTGTTGATTCCTTTATTG
GTGACGCCATTATGGTGGTATTTGGAGCACCACACTCTGGAGGAGATGACGCATACAGAGCGATAGCCTGTGCATTAGAG
ATGCAGGCGACCATGCAAGAGGTGAACACAATGAATCGCAACAGCAGTTTGCCTGAATTAGCAATGGGCATAGGAATTAA
TACAGGTTATGCTATTGTAGGTAACATTGGTTCTCAGAAACGTATGCAATATAGTGCAATTGGTTCTCCGGTTAATCTGG
CATCACGTATCCAAGATCTGACTTTGGGGGGGCAAATTTTAATTTCTGAGGCAACTTACCAGGAAGTTAATCATTCGCTT
GAGTTAAATGGGCATCTCAGAGTAAAAGTTAAGGGAGTTGCTGCTCCTATCACTATTTATGATGTAATCGGTTTGAATAA
AAAATCAGATTCATAG

Upstream 100 bases:

>100_bases
ATATCCTTCATAGCAAGGGTTAGCCACATACAAGTAAACCATCAACTTTATTTCCATTGCTGAATACAATTAACTTATTC
ATTGGTTTAAGCCAGTTAAT

Downstream 100 bases:

>100_bases
AAGTAATAATATCACTCTTTAAAATCATGGGATCAAGAAATTGCTTAAATTACCAATCTCAATGGTATTATGATTGAAAT
AAGCAGCCTAAGGGATAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSALYYNFNNHYASHFVYSPEKIMKKPLDNTEQNRIAALYELKILDTPADERFDRIIRLTSGYLSVPIAFISFIDSKHQW
FKSSCGIGLNKISRNDSFCHYTIQQNKPMIISDALLDERFCNNPYVTNSPNIRFYAGFPLSTVDGFNIGTLCAIDKKPRN
LDETEIQILKDLATLAEDQVNLLDISLLERAVREKNISLTKAKKELEMRNNFIRKVFGSFMSDEIVAALLESKSELKLGG
EERKITILFSDLRNFTTLSEHFPADKIVAALNNHYGKMVDVIEKYNGTVDSFIGDAIMVVFGAPHSGGDDAYRAIACALE
MQATMQEVNTMNRNSSLPELAMGIGINTGYAIVGNIGSQKRMQYSAIGSPVNLASRIQDLTLGGQILISEATYQEVNHSL
ELNGHLRVKVKGVAAPITIYDVIGLNKKSDS

Sequences:

>Translated_431_residues
MSALYYNFNNHYASHFVYSPEKIMKKPLDNTEQNRIAALYELKILDTPADERFDRIIRLTSGYLSVPIAFISFIDSKHQW
FKSSCGIGLNKISRNDSFCHYTIQQNKPMIISDALLDERFCNNPYVTNSPNIRFYAGFPLSTVDGFNIGTLCAIDKKPRN
LDETEIQILKDLATLAEDQVNLLDISLLERAVREKNISLTKAKKELEMRNNFIRKVFGSFMSDEIVAALLESKSELKLGG
EERKITILFSDLRNFTTLSEHFPADKIVAALNNHYGKMVDVIEKYNGTVDSFIGDAIMVVFGAPHSGGDDAYRAIACALE
MQATMQEVNTMNRNSSLPELAMGIGINTGYAIVGNIGSQKRMQYSAIGSPVNLASRIQDLTLGGQILISEATYQEVNHSL
ELNGHLRVKVKGVAAPITIYDVIGLNKKSDS
>Mature_430_residues
SALYYNFNNHYASHFVYSPEKIMKKPLDNTEQNRIAALYELKILDTPADERFDRIIRLTSGYLSVPIAFISFIDSKHQWF
KSSCGIGLNKISRNDSFCHYTIQQNKPMIISDALLDERFCNNPYVTNSPNIRFYAGFPLSTVDGFNIGTLCAIDKKPRNL
DETEIQILKDLATLAEDQVNLLDISLLERAVREKNISLTKAKKELEMRNNFIRKVFGSFMSDEIVAALLESKSELKLGGE
ERKITILFSDLRNFTTLSEHFPADKIVAALNNHYGKMVDVIEKYNGTVDSFIGDAIMVVFGAPHSGGDDAYRAIACALEM
QATMQEVNTMNRNSSLPELAMGIGINTGYAIVGNIGSQKRMQYSAIGSPVNLASRIQDLTLGGQILISEATYQEVNHSLE
LNGHLRVKVKGVAAPITIYDVIGLNKKSDS

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI50959205, Length=159, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4557255, Length=167, Percent_Identity=28.7425149700599, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI148536830, Length=148, Percent_Identity=27.7027027027027, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551720, Length=253, Percent_Identity=26.4822134387352, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71989822, Length=180, Percent_Identity=32.7777777777778, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71989805, Length=180, Percent_Identity=32.7777777777778, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193206632, Length=228, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212645052, Length=260, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995305, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534655, Length=291, Percent_Identity=26.4604810996564, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561802, Length=248, Percent_Identity=28.2258064516129, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330468, Length=259, Percent_Identity=28.957528957529, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330470, Length=259, Percent_Identity=28.957528957529, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI62484298, Length=170, Percent_Identity=30, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI62484477, Length=170, Percent_Identity=30, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076872, Length=151, Percent_Identity=35.0993377483444, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116008008, Length=171, Percent_Identity=29.8245614035088, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574512, Length=151, Percent_Identity=35.0993377483444, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583978, Length=153, Percent_Identity=30.718954248366, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161078020, Length=246, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583976, Length=153, Percent_Identity=28.1045751633987, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24585694, Length=160, Percent_Identity=25.625, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 48120; Mature: 47988

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALYYNFNNHYASHFVYSPEKIMKKPLDNTEQNRIAALYELKILDTPADERFDRIIRLT
CCEEEEECCCCEEHHEEECHHHHHHCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHH
SGYLSVPIAFISFIDSKHQWFKSSCGIGLNKISRNDSFCHYTIQQNKPMIISDALLDERF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCCEEEEHHHHHHHH
CNNPYVTNSPNIRFYAGFPLSTVDGFNIGTLCAIDKKPRNLDETEIQILKDLATLAEDQV
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
NLLDISLLERAVREKNISLTKAKKELEMRNNFIRKVFGSFMSDEIVAALLESKSELKLGG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EERKITILFSDLRNFTTLSEHFPADKIVAALNNHYGKMVDVIEKYNGTVDSFIGDAIMVV
CCCEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEE
FGAPHSGGDDAYRAIACALEMQATMQEVNTMNRNSSLPELAMGIGINTGYAIVGNIGSQK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEECCCCCH
RMQYSAIGSPVNLASRIQDLTLGGQILISEATYQEVNHSLELNGHLRVKVKGVAAPITIY
HHHHHHCCCCHHHHHHHHHHCCCCEEEEECHHHHHCCCEEEECCEEEEEEECEECCEEEE
DVIGLNKKSDS
EEECCCCCCCC
>Mature Secondary Structure 
SALYYNFNNHYASHFVYSPEKIMKKPLDNTEQNRIAALYELKILDTPADERFDRIIRLT
CEEEEECCCCEEHHEEECHHHHHHCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHH
SGYLSVPIAFISFIDSKHQWFKSSCGIGLNKISRNDSFCHYTIQQNKPMIISDALLDERF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCCEEEEHHHHHHHH
CNNPYVTNSPNIRFYAGFPLSTVDGFNIGTLCAIDKKPRNLDETEIQILKDLATLAEDQV
CCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
NLLDISLLERAVREKNISLTKAKKELEMRNNFIRKVFGSFMSDEIVAALLESKSELKLGG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EERKITILFSDLRNFTTLSEHFPADKIVAALNNHYGKMVDVIEKYNGTVDSFIGDAIMVV
CCCEEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEE
FGAPHSGGDDAYRAIACALEMQATMQEVNTMNRNSSLPELAMGIGINTGYAIVGNIGSQK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEECCCCCH
RMQYSAIGSPVNLASRIQDLTLGGQILISEATYQEVNHSLELNGHLRVKVKGVAAPITIY
HHHHHHCCCCHHHHHHHHHHCCCCEEEEECHHHHHCCCEEEECCEEEEEEECEECCEEEE
DVIGLNKKSDS
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]