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The map label for this gene is dacC [H]

Identifier: 54294448

GI number: 54294448

Start: 1688823

End: 1690115

Strand: Reverse

Name: dacC [H]

Synonym: lpl1517

Alternate gene names: 54294448

Gene position: 1690115-1688823 (Counterclockwise)

Preceding gene: 54294460

Following gene: 54294447

Centisome position: 50.52

GC content: 37.35

Gene sequence:

>1293_bases
ATGCCATTTGGCCGCCTGCAAAAGGCTGTGATAAGATACATTTATTTTGCAACTATATCAGGTAATATCATGACCAGAGC
AACGTCTTTTTTATTGACGCTATTATTTTTTATTACTTTATTTGTACAATCTACCAATTCAATGGCTGATGAAGTGCTCC
CCTCCTCTGATTTGCAGAAGCCTTCTCCAACAATCACAACGAAACCTTTTACAACTCCGGCTGCTCCATTGCTTAATGCC
AAAGCTTATATTTTAATTGATGTGAATAGTGGAAAAGTAATTGCAGAAAAGAATAGTGAGGAAAAATTACCACCTGCCAG
TTTGACCAAAATGATGACGCTGTATGTCATTTCTAATGCATTGAAGAGCGGACAAATCCATCTTAATGATATGGTAAGAG
TAAGCCGTGATGCATGGCAGACAGGTGGCTCTCGTATGTTTATAAAAGAGGGAGATCAGGTCTCTGTTGAAGACCTTTTA
AAAGGCATTATAGTAGACTCTGGTAATGACGCTTGTGTGGCAATGGCAGAGCATCTTGGCGGTTCCGAAAATGCTTTTAC
CGACATTATGAATCAGCAAGCTCAAAATCTGGGTATGAAAAATAGTCATTTTACAGACAGTACTGGATTGCCTGATCCTA
ATCTATATACAACTGCTAAAGATTTGGCGATTTTAGGCAGAGCCTTAATACTCGATTTCCCTGAATACTATGACTGGTAT
AAACAAAAATGGTTTACATACAACGGTATACGCCAACCTAATCGAAATCGTTTGTTGTGGCGAGATAGCCAAGTTGATGG
TATAAAAACAGGCCATACCAATGATGCTGGATATTGTCTAGTATCTTCTGCAAAGCGTAATAATATGCGTTTATTAGCTG
TGGTTTTAGGGGAACCCAGTGAATCTGTGCGTGCTGATGACAGTGAAAAATTATTAAATTACGGATTTAGATTTTTTGAA
ACACATCAATTATATAAATCTGGGCAATCAATTGCTGAATTACCGCTTTACAAAGGAACTTCTGACAAAGTTGCTGTGGG
TTTAACAGAAGATCAATTTATTACAATACCTGCCGGTCAATATGAAAGATTAAATATTTCAACTAAAATTTCTAATGATT
TACAAGCTCCTATAAAGAAAGGCGATAAAGTTGGCGATATTATTGTGCAATTTAATAACAATATCGTTTCAAGCAAACCG
CTCTATGCTTTGCAAACAGTGGAGTCAGGTGGATTCTATACCAGAACAAAAGATTCGATAAGGTTAGCATTTAAGCGATG
GTTCGGCTCCTAG

Upstream 100 bases:

>100_bases
AGTTATTACTAATATTACCAAAAAATAATAATTTTCGAAGTGCGATTAAATTAATTCACAACTTATTTAGCTTTATAAAA
AAAATATTAATATTTTTAAT

Downstream 100 bases:

>100_bases
GATATTTTCATAATGAATATCGCATTTGTTAACGGCAAGTATTGTTGTCACTCTGAAGCAAAAATTTCAATATTTGATCG
AGGCTTTCTTTTTGGGGACT

Product: hypothetical protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MPFGRLQKAVIRYIYFATISGNIMTRATSFLLTLLFFITLFVQSTNSMADEVLPSSDLQKPSPTITTKPFTTPAAPLLNA
KAYILIDVNSGKVIAEKNSEEKLPPASLTKMMTLYVISNALKSGQIHLNDMVRVSRDAWQTGGSRMFIKEGDQVSVEDLL
KGIIVDSGNDACVAMAEHLGGSENAFTDIMNQQAQNLGMKNSHFTDSTGLPDPNLYTTAKDLAILGRALILDFPEYYDWY
KQKWFTYNGIRQPNRNRLLWRDSQVDGIKTGHTNDAGYCLVSSAKRNNMRLLAVVLGEPSESVRADDSEKLLNYGFRFFE
THQLYKSGQSIAELPLYKGTSDKVAVGLTEDQFITIPAGQYERLNISTKISNDLQAPIKKGDKVGDIIVQFNNNIVSSKP
LYALQTVESGGFYTRTKDSIRLAFKRWFGS

Sequences:

>Translated_430_residues
MPFGRLQKAVIRYIYFATISGNIMTRATSFLLTLLFFITLFVQSTNSMADEVLPSSDLQKPSPTITTKPFTTPAAPLLNA
KAYILIDVNSGKVIAEKNSEEKLPPASLTKMMTLYVISNALKSGQIHLNDMVRVSRDAWQTGGSRMFIKEGDQVSVEDLL
KGIIVDSGNDACVAMAEHLGGSENAFTDIMNQQAQNLGMKNSHFTDSTGLPDPNLYTTAKDLAILGRALILDFPEYYDWY
KQKWFTYNGIRQPNRNRLLWRDSQVDGIKTGHTNDAGYCLVSSAKRNNMRLLAVVLGEPSESVRADDSEKLLNYGFRFFE
THQLYKSGQSIAELPLYKGTSDKVAVGLTEDQFITIPAGQYERLNISTKISNDLQAPIKKGDKVGDIIVQFNNNIVSSKP
LYALQTVESGGFYTRTKDSIRLAFKRWFGS
>Mature_429_residues
PFGRLQKAVIRYIYFATISGNIMTRATSFLLTLLFFITLFVQSTNSMADEVLPSSDLQKPSPTITTKPFTTPAAPLLNAK
AYILIDVNSGKVIAEKNSEEKLPPASLTKMMTLYVISNALKSGQIHLNDMVRVSRDAWQTGGSRMFIKEGDQVSVEDLLK
GIIVDSGNDACVAMAEHLGGSENAFTDIMNQQAQNLGMKNSHFTDSTGLPDPNLYTTAKDLAILGRALILDFPEYYDWYK
QKWFTYNGIRQPNRNRLLWRDSQVDGIKTGHTNDAGYCLVSSAKRNNMRLLAVVLGEPSESVRADDSEKLLNYGFRFFET
HQLYKSGQSIAELPLYKGTSDKVAVGLTEDQFITIPAGQYERLNISTKISNDLQAPIKKGDKVGDIIVQFNNNIVSSKPL
YALQTVESGGFYTRTKDSIRLAFKRWFGS

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=367, Percent_Identity=48.5013623978202, Blast_Score=347, Evalue=8e-97,
Organism=Escherichia coli, GI1786851, Length=365, Percent_Identity=46.8493150684932, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI87082022, Length=358, Percent_Identity=38.5474860335196, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI87082054, Length=249, Percent_Identity=28.5140562248996, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 47913; Mature: 47782

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFGRLQKAVIRYIYFATISGNIMTRATSFLLTLLFFITLFVQSTNSMADEVLPSSDLQK
CCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
PSPTITTKPFTTPAAPLLNAKAYILIDVNSGKVIAEKNSEEKLPPASLTKMMTLYVISNA
CCCCEEECCCCCCCCHHHCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LKSGQIHLNDMVRVSRDAWQTGGSRMFIKEGDQVSVEDLLKGIIVDSGNDACVAMAEHLG
HHCCCEEEHHHHHHHHHHHHCCCCEEEEECCCEECHHHHHHEEEEECCCCHHHHHHHHCC
GSENAFTDIMNQQAQNLGMKNSHFTDSTGLPDPNLYTTAKDLAILGRALILDFPEYYDWY
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCHHHHHHH
KQKWFTYNGIRQPNRNRLLWRDSQVDGIKTGHTNDAGYCLVSSAKRNNMRLLAVVLGEPS
HHHCEEECCCCCCCCCCEEEECCCCCCEECCCCCCCCEEEEECCCCCCEEEEEEEECCCC
ESVRADDSEKLLNYGFRFFETHQLYKSGQSIAELPLYKGTSDKVAVGLTEDQFITIPAGQ
HHCCCCCHHHHHHHCHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEECCCCEEEECCCC
YERLNISTKISNDLQAPIKKGDKVGDIIVQFNNNIVSSKPLYALQTVESGGFYTRTKDSI
CEEEEEEECCCCHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCEEECCHHH
RLAFKRWFGS
HHHHHHHHCC
>Mature Secondary Structure 
PFGRLQKAVIRYIYFATISGNIMTRATSFLLTLLFFITLFVQSTNSMADEVLPSSDLQK
CHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
PSPTITTKPFTTPAAPLLNAKAYILIDVNSGKVIAEKNSEEKLPPASLTKMMTLYVISNA
CCCCEEECCCCCCCCHHHCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LKSGQIHLNDMVRVSRDAWQTGGSRMFIKEGDQVSVEDLLKGIIVDSGNDACVAMAEHLG
HHCCCEEEHHHHHHHHHHHHCCCCEEEEECCCEECHHHHHHEEEEECCCCHHHHHHHHCC
GSENAFTDIMNQQAQNLGMKNSHFTDSTGLPDPNLYTTAKDLAILGRALILDFPEYYDWY
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCHHHHHHH
KQKWFTYNGIRQPNRNRLLWRDSQVDGIKTGHTNDAGYCLVSSAKRNNMRLLAVVLGEPS
HHHCEEECCCCCCCCCCEEEECCCCCCEECCCCCCCCEEEEECCCCCCEEEEEEEECCCC
ESVRADDSEKLLNYGFRFFETHQLYKSGQSIAELPLYKGTSDKVAVGLTEDQFITIPAGQ
HHCCCCCHHHHHHHCHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEECCCCEEEECCCC
YERLNISTKISNDLQAPIKKGDKVGDIIVQFNNNIVSSKPLYALQTVESGGFYTRTKDSI
CEEEEEEECCCCHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCEEECCHHH
RLAFKRWFGS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]