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The map label for this gene is ruvB [H]

Identifier: 54294380

GI number: 54294380

Start: 1617434

End: 1618444

Strand: Direct

Name: ruvB [H]

Synonym: lpl1449

Alternate gene names: 54294380

Gene position: 1617434-1618444 (Clockwise)

Preceding gene: 54294379

Following gene: 54294381

Centisome position: 48.34

GC content: 42.14

Gene sequence:

>1011_bases
ATGCTCGAAAGTGATCGCCTAATAAGTAGTCAAAGTATTGTCTCGGAAGACGCAATGGATAGAGCCATCAGGCCGCTTAG
CTTGAGCGAGTACGTAGGGCAAGATTCTGTTAGCTCACAGATGCAGATATTTATCAATGCAGCAAGAAAGAGAAACGATC
CTTTGGATCATGTTCTTATTTTTGGCCCACCTGGCCTTGGTAAAACTACCCTTGCAAATATCATAGCTCACGAAATGGGA
GTGAATATCCGACAAACTTCTGGGCCAGTGATTGAGCGTGCTGGAGATATTGCTGCTATATTGACGAATCTACAACAAAA
TGATGTACTATTTATTGATGAAATTCATAGATTAAGTCCTGTTATAGAAGAAATTCTTTATCCAGCCATGGAAGATTATA
AGTTGGATATCATGATAGGCGAGGGGCCAGCAGCACGATCTATTAAATTGGAGTTACCTCCCTTTACATTAATTGGAGCA
ACGACGAGAGCAGGGTTGCTTACCTCGCCATTAAGGGATAGATTTGGTATAGTGCAACGTTTGGAATATTATTCTGTTGA
TTCGCTTACCCAGATTGTGGCACGCTCCGCGCATTTGCTTGGTGTCCCTACAAAACCCGAAGGAGCCAGAGAAGTTGCAT
TACGCTCCAGAGGAACACCACGAATAGCCAATCGCCTGTTAAGAAGAGTCAGGGATTATTCTGAAGTGAAAGGAAATGGC
ATCATTACTGTTGATATGGCCCAACAAGCATTGGAAATGCTTGAAGTGGATCAGCACGGGTTTGATTTAATGGATAGAAA
ATTATTGTTAGCGGTAATAGAACACTTCAATGGTGGTCCAGTAGGCATAGATAGTATTGCAGCCGCTATTGGCGAAGAAA
AAGGAACTATAGAAGATGTTTTAGAGCCATTTTTAATACAACAAGGCTTTCTAATGCGCACTCCTCGCGGTAGAATAGCC
ACTTCGAAAGCTTATCAGCATTTTGGCTTTAGTGCGATCGAACAGGAATAA

Upstream 100 bases:

>100_bases
AATTGCATTTAATTATTAAATAAATAAGCTTACAAAGATCTGCTATTAGATAAACCTATGTTAAAATGCCTTCATCCGAA
TGAACCCGATAAAACCTCTT

Downstream 100 bases:

>100_bases
CACATGAATCTTATATCAAATCATCAGCATAACATTAGAGTCTATGCAGAAGATGTTGATTATATGGGAATTGTTTATCA
TGCTAACTACCTTTGTTATT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMG
VNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGA
TTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREVALRSRGTPRIANRLLRRVRDYSEVKGNG
IITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIA
TSKAYQHFGFSAIEQE

Sequences:

>Translated_336_residues
MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMG
VNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGA
TTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREVALRSRGTPRIANRLLRRVRDYSEVKGNG
IITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIA
TSKAYQHFGFSAIEQE
>Mature_336_residues
MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMG
VNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGA
TTRAGLLTSPLRDRFGIVQRLEYYSVDSLTQIVARSAHLLGVPTKPEGAREVALRSRGTPRIANRLLRRVRDYSEVKGNG
IITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIA
TSKAYQHFGFSAIEQE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=72.4550898203593, Blast_Score=498, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37091; Mature: 37091

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLI
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEE
FGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHCCHHHHHHHCCCCCCEEEHHHHHHHHH
VIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIVQR
HHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHHHHHHHHH
LEYYSVDSLTQIVARSAHLLGVPTKPEGAREVALRSRGTPRIANRLLRRVRDYSEVKGNG
HHHHCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
IITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDV
EEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHH
LEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
HHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MLESDRLISSQSIVSEDAMDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLI
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEE
FGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHCCHHHHHHHCCCCCCEEEHHHHHHHHH
VIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIVQR
HHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHHHHHHHHH
LEYYSVDSLTQIVARSAHLLGVPTKPEGAREVALRSRGTPRIANRLLRRVRDYSEVKGNG
HHHHCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
IITVDMAQQALEMLEVDQHGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDV
EEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHH
LEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
HHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA