Click here to switch to the map view.

The map label for this gene is truD [H]

Identifier: 54294332

GI number: 54294332

Start: 1562188

End: 1563204

Strand: Direct

Name: truD [H]

Synonym: lpl1400

Alternate gene names: 54294332

Gene position: 1562188-1563204 (Clockwise)

Preceding gene: 54294330

Following gene: 54294333

Centisome position: 46.69

GC content: 38.54

Gene sequence:

>1017_bases
ATGTACTCTTTAAATTGGCCACGTGCCTATGGTATTCCAAATTCTACAGCTACTTTTAAGTTATGTCCGGAAGATTTTCA
AGTGAATGAATTGTTTGAAGGACAGTTTAGCGGTGAAGGAGAACACATAGTTCTTAAAATTGAAAAAAAAGGACTAACCA
CTGAACAAGTTATCAAATCATTGGCTAGGCTAATTAACAAACCGATAAAACTTATAAGTTACGCGGGATTAAAAGACAAA
CAGGCATTAACAACGCAATGGCTCAGTATTCATGCACCTGGAGAGGTAATTGAGGGTATAGAAACACTAGAAGCACCAGG
ATGGAAAATACTGGAATGCACGCGTCATAATAAAAAACTGAGGCCAGGTTTTTTATCAGGAAATCACTTCACAATCACGT
TAAGAAATGTCTCTGATGAGAGTGATCTAATACATCGTATTGAACAAATTAAATTTAAAGGTGTTCCAAATTATTTCGGT
GAGCAGCGTTTTGGTCGAGATGGTGGAAATTTAATTAAAGCAGAGGAAATACTAGTACAGGGACGCAAAGTAAAGGATAG
ATTTTTAAAAGGAATGTATTTTTCCGCAGCCCGATCATGGCTATATAATTTGATCCTGTCTCGCCGTGTAAAGGAATCAT
CATGGAATTTGCCCTTATTGGGGGATGTCATACAGCTTGTTGGATCAAACAGTATATTTGTTAATGATAAAAGCCTGGAT
GAGCAATTGTTGCAACGAATCGGTGAGAAAGATGTTTCTCCAGCAAGCCCTCTGCCTGGCAGGAGTAAGAATCTTGTAAA
AGGGACAGCTTTGCAAATAATAAATGAGGTTTATGCGGAATGGTCTGCCTGGTTGGATGGATTGGAAAAAAATGGTTTGG
AAGAAGCCTGGCGTGCAAATATCCTTTATGCAGAACAGATTGAATATAGGATAAACCAAGGTACAGTTGAGCTTTCGTTT
GTCTTGCCGGCTGGTGCTTACGCGACAGTGGTATTACGTGAATTGGTTCAATATTAA

Upstream 100 bases:

>100_bases
ATAAATTATCTATCAGCTAAACCAATAAGTTCTGTATCTCTTGATATCATAGTGAATTTGTGGATTTAGTTTAGAACCCT
TTTTGTTGAAGGAGATCTTG

Downstream 100 bases:

>100_bases
GCTTTGTTTGCACTTGAATAGCACTTTAGTCAATGTGGAGTAATTATTTTAATTGAATTGATGAGTTAATCACTATGTTT
GATGTTATGCCATAATAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MYSLNWPRAYGIPNSTATFKLCPEDFQVNELFEGQFSGEGEHIVLKIEKKGLTTEQVIKSLARLINKPIKLISYAGLKDK
QALTTQWLSIHAPGEVIEGIETLEAPGWKILECTRHNKKLRPGFLSGNHFTITLRNVSDESDLIHRIEQIKFKGVPNYFG
EQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSLD
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINEVYAEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSF
VLPAGAYATVVLRELVQY

Sequences:

>Translated_338_residues
MYSLNWPRAYGIPNSTATFKLCPEDFQVNELFEGQFSGEGEHIVLKIEKKGLTTEQVIKSLARLINKPIKLISYAGLKDK
QALTTQWLSIHAPGEVIEGIETLEAPGWKILECTRHNKKLRPGFLSGNHFTITLRNVSDESDLIHRIEQIKFKGVPNYFG
EQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSLD
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINEVYAEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSF
VLPAGAYATVVLRELVQY
>Mature_338_residues
MYSLNWPRAYGIPNSTATFKLCPEDFQVNELFEGQFSGEGEHIVLKIEKKGLTTEQVIKSLARLINKPIKLISYAGLKDK
QALTTQWLSIHAPGEVIEGIETLEAPGWKILECTRHNKKLRPGFLSGNHFTITLRNVSDESDLIHRIEQIKFKGVPNYFG
EQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSLD
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINEVYAEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSF
VLPAGAYATVVLRELVQY

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=328, Percent_Identity=38.4146341463415, Blast_Score=214, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 38263; Mature: 38263

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSLNWPRAYGIPNSTATFKLCPEDFQVNELFEGQFSGEGEHIVLKIEKKGLTTEQVIKS
CCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHH
LARLINKPIKLISYAGLKDKQALTTQWLSIHAPGEVIEGIETLEAPGWKILECTRHNKKL
HHHHHHCHHHHHHHCCCCCCHHHHHHHEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
RPGFLSGNHFTITLRNVSDESDLIHRIEQIKFKGVPNYFGEQRFGRDGGNLIKAEEILVQ
CCCEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEHHHHHHHC
GRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCHHH
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINEVYAEWSAWLDGLEKNGLEEAWRAN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
ILYAEQIEYRINQGTVELSFVLPAGAYATVVLRELVQY
CEEEEHHHEEECCCEEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYSLNWPRAYGIPNSTATFKLCPEDFQVNELFEGQFSGEGEHIVLKIEKKGLTTEQVIKS
CCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHH
LARLINKPIKLISYAGLKDKQALTTQWLSIHAPGEVIEGIETLEAPGWKILECTRHNKKL
HHHHHHCHHHHHHHCCCCCCHHHHHHHEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
RPGFLSGNHFTITLRNVSDESDLIHRIEQIKFKGVPNYFGEQRFGRDGGNLIKAEEILVQ
CCCEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEHHHHHHHC
GRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEECCHHH
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINEVYAEWSAWLDGLEKNGLEEAWRAN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
ILYAEQIEYRINQGTVELSFVLPAGAYATVVLRELVQY
CEEEEHHHEEECCCEEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA