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The map label for this gene is ubiA [H]

Identifier: 54294316

GI number: 54294316

Start: 1541127

End: 1541975

Strand: Direct

Name: ubiA [H]

Synonym: lpl1381

Alternate gene names: 54294316

Gene position: 1541127-1541975 (Clockwise)

Preceding gene: 54294315

Following gene: 54294317

Centisome position: 46.06

GC content: 32.86

Gene sequence:

>849_bases
ATGATTCCCTGGAATGCCTATGTCAGATTATTACGCTTAAATAAACCAATAGGAATTTTATTACTTTGGTATCCCACTGC
ATGGGCACTTTGGATGGCAAATCAGGGCTTTCCTTCTATTGATTTGCTTATGATTTTTTTATTAGGTACAGTATTCATGC
GTTCCGCAGGTTGTGTTATTAACGATATTGCTGACAGGCATATTGATAGGCATGTAGCCCGAACCCAATTTCGCCCCTTG
ACTTCTGGAGAGGTCAGCTTGTCTGAGGCATTTATTTTATTGTTTATATTACTTTGTGCCTCATTGTTTTTATTATTAAA
ACTTCCAATCAATTGTTTTTATTTTGCGGTTATTTCCGTACTAATTACTTTTTTATACCCATTTTGTAAACGATTTTTCA
ATGCTCCACAACTGGTATTAGGTTTGGCTTTTTCCATGGGTATTCCTATGGCATTTATTGCCTCAGGGAAAAATTTAAAT
AGCGATTTTATTGTATTGTTTTTAATTAATTTTTCCTGGATTATCGCTTATGACACGATGTATGCGATGACTGATAAAGC
TGATGATTTAAAAATAGGAGTCAAATCGACTGCAATATATTTTGCAAGTTATGATAGATTAATTATTGCTTTGCTACTGA
TTTTTTTGCATTCTTTATGGTTGGTATGGGCAATAAATAAGAACGTAGAATGTTTTTTTTATTTGTTATGGTGTACCGCT
GCTGGAATACTGACTTATCAACTAAAGTTAATTTATGCAAGAATACCTAAAAATTGTTTTAAAGCATTTTTAGTGAGTGG
TTATTATGGATTAGTAATGTGGTTTGCCGTTGGATTAGCATTGATTTAA

Upstream 100 bases:

>100_bases
AATACTCTCAGATGTGGGTCAGGTTTACGGAGCTAGTATTTCAGGAAAAGAGTTCTTTTTATTTGGTTGAAATCTTGTTA
CCAGAGCTGGAAAATTTATT

Downstream 100 bases:

>100_bases
ATAATATGTTAATAGAAAATTTGTTGTGCCAAATGATTATGGGTGTCGAAAATTCCTTTATAAGACAGGCTTTAGAAGAA
AAAATCCAACACCAACCCAT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLLGTVFMRSAGCVINDIADRHIDRHVARTQFRPL
TSGEVSLSEAFILLFILLCASLFLLLKLPINCFYFAVISVLITFLYPFCKRFFNAPQLVLGLAFSMGIPMAFIASGKNLN
SDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNVECFFYLLWCTA
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI

Sequences:

>Translated_282_residues
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLLGTVFMRSAGCVINDIADRHIDRHVARTQFRPL
TSGEVSLSEAFILLFILLCASLFLLLKLPINCFYFAVISVLITFLYPFCKRFFNAPQLVLGLAFSMGIPMAFIASGKNLN
SDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNVECFFYLLWCTA
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
>Mature_282_residues
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLLGTVFMRSAGCVINDIADRHIDRHVARTQFRPL
TSGEVSLSEAFILLFILLCASLFLLLKLPINCFYFAVISVLITFLYPFCKRFFNAPQLVLGLAFSMGIPMAFIASGKNLN
SDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNVECFFYLLWCTA
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=33.3333333333333, Blast_Score=148, Evalue=5e-36,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=43.2727272727273, Blast_Score=219, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17553718, Length=272, Percent_Identity=32.7205882352941, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32565247, Length=272, Percent_Identity=31.6176470588235, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17553720, Length=181, Percent_Identity=37.0165745856354, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=41.1347517730496, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=41.304347826087, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324370, Length=273, Percent_Identity=34.4322344322344, Blast_Score=146, Evalue=4e-36,
Organism=Drosophila melanogaster, GI21355567, Length=278, Percent_Identity=34.5323741007194, Blast_Score=157, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 32237; Mature: 32237

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLLGTVFMRSAGCVI
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHH
NDIADRHIDRHVARTQFRPLTSGEVSLSEAFILLFILLCASLFLLLKLPINCFYFAVISV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITFLYPFCKRFFNAPQLVLGLAFSMGIPMAFIASGKNLNSDFIVLFLINFSWIIAYDTM
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHH
YAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNVECFFYLLWCTA
HHHCCCCCCCEEEHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLLGTVFMRSAGCVI
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHH
NDIADRHIDRHVARTQFRPLTSGEVSLSEAFILLFILLCASLFLLLKLPINCFYFAVISV
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LITFLYPFCKRFFNAPQLVLGLAFSMGIPMAFIASGKNLNSDFIVLFLINFSWIIAYDTM
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEHHHHHHHHHHHH
YAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNVECFFYLLWCTA
HHHCCCCCCCEEEHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA