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The map label for this gene is lidH [H]

Identifier: 54294288

GI number: 54294288

Start: 1507968

End: 1508756

Strand: Direct

Name: lidH [H]

Synonym: lpl1353

Alternate gene names: 54294288

Gene position: 1507968-1508756 (Clockwise)

Preceding gene: 54294287

Following gene: 54294289

Centisome position: 45.07

GC content: 39.8

Gene sequence:

>789_bases
GTGCTGGTCGACTCTCATTGTCATTTAAATTTTATCGATTTGACTCATTTTCATCATGATCTTGCTCAGGTAATCAATCA
GGCTCGCGAGAATGAGGTGGAGCATTTCTTGTCTGTTTGTGTTGAGTTGAGCGATTATCCTCAATTAGAGCGTTTAGCAA
AGGATTATCCTGATATTAGCATTTCTGTTGGAGTGCATCCGAATAGTGAAATGAATTATCCTGTTACGGCACAGATGTTA
TGTGAATTGGCTCAAAATCCTGCCTGTATTGCCATAGGAGAAACAGGGCTTGATTATTATCGTAATCCCACTGAGGAAGC
TCAATCTTTGCAACGAGATCGTTTCAGGGAACATATCAAGGCGGCACTTATAACTTCCAAGCCGTTAATTATTCATACCA
GGCAAGCTGCTGAAGATACTTTGTTGATGATGGCTAAGGAAGGAGCTAGTCAGATAGGCGGAGTCATGCACTGTTTTGCT
GAAGACTTGGATATTGCGCAAAGAGCAATTGATTTAAATTTTTATATATCATTTTCCGGGATAGTTACTTTTAAAAATGC
TGTTTCATTGCAAGATGTAGCCAGGCAGATACCTTTAGAGAGGATACTGATAGAGACAGATTCACCTTATTTGGCTCCAG
TTCCACACAGAGGAAAGCAAAATCATCCCGCTTTGGTGAAGCACGTAGCAGAAGCTATCGCACAACTCAGAGGGATGGAT
TTCCAAGAGATAGCAGAAATCACTACAAACAATTTTTACAATTGTTTTAATATCAAACGACAAGGATAA

Upstream 100 bases:

>100_bases
TTGGCAGGAATGCTAAAATCATGTCAGGTTACAGATACTATATAGAATTTTCATTTATTCATGAACAATATATTCATTGA
TATTATTTTGGGGTATAAAG

Downstream 100 bases:

>100_bases
ATCATTGGTAAATCGTAGTTCTCAACTTCAAAATAGAAGCGGTAATTTTTTTGCCTGTGAATAAAGGTTTTAGTAGTATT
GACATATCCTATTGCAAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLVDSHCHLNFIDLTHFHHDLAQVINQARENEVEHFLSVCVELSDYPQLERLAKDYPDISISVGVHPNSEMNYPVTAQML
CELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFA
EDLDIAQRAIDLNFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAEAIAQLRGMD
FQEIAEITTNNFYNCFNIKRQG

Sequences:

>Translated_262_residues
MLVDSHCHLNFIDLTHFHHDLAQVINQARENEVEHFLSVCVELSDYPQLERLAKDYPDISISVGVHPNSEMNYPVTAQML
CELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFA
EDLDIAQRAIDLNFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAEAIAQLRGMD
FQEIAEITTNNFYNCFNIKRQG
>Mature_262_residues
MLVDSHCHLNFIDLTHFHHDLAQVINQARENEVEHFLSVCVELSDYPQLERLAKDYPDISISVGVHPNSEMNYPVTAQML
CELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFA
EDLDIAQRAIDLNFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAEAIAQLRGMD
FQEIAEITTNNFYNCFNIKRQG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=29.0441176470588, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225903424, Length=251, Percent_Identity=29.0836653386454, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=28.4644194756554, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=28.4644194756554, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=27.1317829457364, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI14042943, Length=266, Percent_Identity=28.1954887218045, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI225903439, Length=227, Percent_Identity=28.1938325991189, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=28.3842794759825, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=46.5116279069767, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI48994985, Length=250, Percent_Identity=30, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87082439, Length=261, Percent_Identity=29.8850574712644, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=27.6752767527675, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=25.9398496240602, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=213, Percent_Identity=27.6995305164319, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=213, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648690, Length=247, Percent_Identity=30.3643724696356, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586117, Length=216, Percent_Identity=30.0925925925926, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330018, Length=216, Percent_Identity=30.0925925925926, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 29595; Mature: 29595

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLNFIDLTHFHHDLAQVINQARENEVEHFLSVCVELSDYPQLERLAKDYPDIS
CEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCE
ISVGVHPNSEMNYPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIK
EEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHH
AALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFAEDLDIAQRAIDLNFYISFSG
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEC
IVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAEAIAQLRGMD
EEEEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
FQEIAEITTNNFYNCFNIKRQG
HHHHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure
MLVDSHCHLNFIDLTHFHHDLAQVINQARENEVEHFLSVCVELSDYPQLERLAKDYPDIS
CEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCE
ISVGVHPNSEMNYPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIK
EEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHH
AALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFAEDLDIAQRAIDLNFYISFSG
HHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEC
IVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAEAIAQLRGMD
EEEEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
FQEIAEITTNNFYNCFNIKRQG
HHHHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]