Click here to switch to the map view.

The map label for this gene is erpA [H]

Identifier: 54294274

GI number: 54294274

Start: 1497010

End: 1497402

Strand: Reverse

Name: erpA [H]

Synonym: lpl1339

Alternate gene names: 54294274

Gene position: 1497402-1497010 (Counterclockwise)

Preceding gene: 54294275

Following gene: 54294271

Centisome position: 44.76

GC content: 35.62

Gene sequence:

>393_bases
ATGGCCAGTGTTGACGTATCCCAAAACACTTCAGATATCAATTTTTCTGTCAGCGCAGCTGATAAAGTAGCAGAATTAAT
TAAAGAAGAAGATAATTCCGATTTGAATTTACGCGTCTCAATTACAGGTGGTGGTTGTTCTGGATTTCAATATGGATTTA
GCTTTGATGAACAAATCAATGATGACGACACGGTTATCATACAACAATGTTCTGATGGAAAATCTTCTGTCAAATTGCTA
ATTGATTCAATGAGTTACCAATATCTGCATGATGCGGAAATTGATTACATTAAAGGAATTCAAGGAGAGCAATTTGTCAT
ACGCAATCCTAATGCAAAAACGACTTGTGGTTGCGGCTCTTCATTTAGTATTGGTGATGAGGATGATTTATAA

Upstream 100 bases:

>100_bases
TTTCTCTGGTCCCCATACCAATTTATGGATTGAGACTACGAAACAACTCACATTATTGATATAATGAATAATAATGGTAG
TAATTATTTTGGAGCTAAGT

Downstream 100 bases:

>100_bases
AAAAATCACTGCCTGAAACTCAAGGCAGTGATCTTAGCTTTTTTACGGACGAACTGCTTATTATTTCTTAAGCACCTCGG
GTAGGAACAGGCGATGGAAA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MASVDVSQNTSDINFSVSAADKVAELIKEEDNSDLNLRVSITGGGCSGFQYGFSFDEQINDDDTVIIQQCSDGKSSVKLL
IDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL

Sequences:

>Translated_130_residues
MASVDVSQNTSDINFSVSAADKVAELIKEEDNSDLNLRVSITGGGCSGFQYGFSFDEQINDDDTVIIQQCSDGKSSVKLL
IDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL
>Mature_129_residues
ASVDVSQNTSDINFSVSAADKVAELIKEEDNSDLNLRVSITGGGCSGFQYGFSFDEQINDDDTVIIQQCSDGKSSVKLLI
DSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGSSFSIGDEDDL

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=103, Percent_Identity=39.8058252427184, Blast_Score=74, Evalue=4e-14,
Organism=Homo sapiens, GI52426768, Length=112, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786351, Length=112, Percent_Identity=55.3571428571429, Blast_Score=134, Evalue=2e-33,
Organism=Escherichia coli, GI1788877, Length=112, Percent_Identity=32.1428571428571, Blast_Score=63, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=32.4074074074074, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325324, Length=135, Percent_Identity=32.5925925925926, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=112, Percent_Identity=33.9285714285714, Blast_Score=61, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24649697, Length=119, Percent_Identity=35.2941176470588, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 14096; Mature: 13965

Theoretical pI: Translated: 3.80; Mature: 3.80

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVDVSQNTSDINFSVSAADKVAELIKEEDNSDLNLRVSITGGGCSGFQYGFSFDEQIN
CCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
DDDTVIIQQCSDGKSSVKLLIDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGS
CCCEEEEEECCCCCCEEEEEEECCCCEEECCCCCCEECCCCCCEEEEECCCCCCEECCCC
SFSIGDEDDL
CCCCCCCCCC
>Mature Secondary Structure 
ASVDVSQNTSDINFSVSAADKVAELIKEEDNSDLNLRVSITGGGCSGFQYGFSFDEQIN
CCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
DDDTVIIQQCSDGKSSVKLLIDSMSYQYLHDAEIDYIKGIQGEQFVIRNPNAKTTCGCGS
CCCEEEEEECCCCCCEEEEEEECCCCEEECCCCCCEECCCCCCEEEEECCCCCCEECCCC
SFSIGDEDDL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA