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The map label for this gene is yciR [C]

Identifier: 54293995

GI number: 54293995

Start: 1181993

End: 1183513

Strand: Direct

Name: yciR [C]

Synonym: lpl1054

Alternate gene names: 54293995

Gene position: 1181993-1183513 (Clockwise)

Preceding gene: 54293994

Following gene: 54293998

Centisome position: 35.33

GC content: 38.59

Gene sequence:

>1521_bases
ATGATCATTGTCGTTTGGAGATTACCTTTGAGTGATGGGAACAAAGCATTATTTGAGCGCTCTTATTATCGCGAAAGAAA
AGCTCGCGAGGAAGCCGAATTATTATTGGAAAATAAGACAAGGGAACTTCATTTACTGAACCAGGATTTGGAAAAAAAGA
ATGCTGAACTGATAAAAACGCTAAAAGATTTAGAGAGGGTACAAAAAAAATTATCGAAATTAGCCCATTTTGATGTATTA
AGCCGATTACCCAATCGATTGCAGTTTGAACTGGATTTAAAACGTGAGATTGCCAGGTCAAAAAGATACGGTCGTCATCT
GGCTCTGTTAAGCATCGATTTGGATTTTTTTAAAAATGTGAATGATCGCTTTGGTCATGATGTCGGTGATGGTCTATTGC
GTGAAGTAGCAAAGCGTCTTTGCTCCAGTCTTCGCGAAGAAGATTGTGTGGCTCGATTAGGAGGAGATGAGTTTGCTGTT
ATTTTGACAGAAATTAATAACCCACAACAGGCAAAATTAGTGGCCAATAATATGATTCAAAAGATGGGTAAGCCATTCCA
TATTAAAGGTCATACAGTCATGATTGGAATCAGTATAGGAATTGCTTACTTTCCTGATGCCGGTGATGAGGCAATAACTC
TTCGTAAGAATGCCGATATTGCTTTATACAACGCCAAAGAATGTGGTCGAAATAATTGCCAAATCTTCACACCATCCCTT
AGAAAACAATATTCAAAACGCTTAGGAATAGGAACCGAGTTGCATCTTGCTTTGGAGCGACAAGAATTTTTTCTTGTTTA
TCAGCCCCGGGTTGATTTAAAAACGAATACTATGGTTGGGATGGAGGTCTTATTACGTTGGCAACATCCCAAGCGGGGTG
TTGTTTTTCCTGATGAATTCATCGCCGTTGCAGAGCATTTTAACTTGATTATTCCAATTGGTGAATGGGTTTTACGAACC
GCGTGCAGGCAGTATGTGGATTGGAAAAAGAGATACGCTCCTTTCAATTGTACCTTGGCGATTAATATTTCGCTTCATCA
ATTTCAGCACAAAGGGTTTATTTCCTCTGTGAAGCACATTTTACAGGAATATCAAATGCCATCGGATTGGTTAGAGCTTG
AAATTACGGAAGCAACGGCAGTCAATTTTTTGGGAAAAATTGAAGAGACATTAAGTGCCCTTCGCAATATGGGGATAAAA
CTTGCTTTTGATAATTTTGGCTCAGGGTATTCTTTTTTATCGCACTTAAAAAATTCACCCATCCAATCCATCAAACTGAA
ACAAGCCTTAATTGAAGATGCTCATCTCAGAGAAAATGATAATTTAATTATCAAATCGACGATTGCTTTGTCGCAAGAAT
TGGGATTGAATGTGGTTGTGGGTGGTGTCGAAACAGAAGAACAACTCAATTTTTTACGGTCAAGTCACTGTTTCGAAGTG
CAAGGCTATTACAGTAGTAAACCGTTAACAGTAGTACAGATGACGCAATTTATCGAGGAAAGGAACTCCAAAGGGTTGTA
G

Upstream 100 bases:

>100_bases
AGAAGGCTCTGTCATTTTGCAATGGGTCTCATCCAGGGAGCAGCGCAGCATTTTAAAAAGAGAATTACCATTAATCAGAC
TCACTGCATGTTGAAAAAAG

Downstream 100 bases:

>100_bases
CTTCATGTCGGTTCGTTCCCATCAAAAAATAACACCAACTGAGCTGCCAAAAGTAATTTGGTCCAAATGGATAAGTTAAT
AAGCCCCGCTTTATTGGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MIIVVWRLPLSDGNKALFERSYYRERKAREEAELLLENKTRELHLLNQDLEKKNAELIKTLKDLERVQKKLSKLAHFDVL
SRLPNRLQFELDLKREIARSKRYGRHLALLSIDLDFFKNVNDRFGHDVGDGLLREVAKRLCSSLREEDCVARLGGDEFAV
ILTEINNPQQAKLVANNMIQKMGKPFHIKGHTVMIGISIGIAYFPDAGDEAITLRKNADIALYNAKECGRNNCQIFTPSL
RKQYSKRLGIGTELHLALERQEFFLVYQPRVDLKTNTMVGMEVLLRWQHPKRGVVFPDEFIAVAEHFNLIIPIGEWVLRT
ACRQYVDWKKRYAPFNCTLAINISLHQFQHKGFISSVKHILQEYQMPSDWLELEITEATAVNFLGKIEETLSALRNMGIK
LAFDNFGSGYSFLSHLKNSPIQSIKLKQALIEDAHLRENDNLIIKSTIALSQELGLNVVVGGVETEEQLNFLRSSHCFEV
QGYYSSKPLTVVQMTQFIEERNSKGL

Sequences:

>Translated_506_residues
MIIVVWRLPLSDGNKALFERSYYRERKAREEAELLLENKTRELHLLNQDLEKKNAELIKTLKDLERVQKKLSKLAHFDVL
SRLPNRLQFELDLKREIARSKRYGRHLALLSIDLDFFKNVNDRFGHDVGDGLLREVAKRLCSSLREEDCVARLGGDEFAV
ILTEINNPQQAKLVANNMIQKMGKPFHIKGHTVMIGISIGIAYFPDAGDEAITLRKNADIALYNAKECGRNNCQIFTPSL
RKQYSKRLGIGTELHLALERQEFFLVYQPRVDLKTNTMVGMEVLLRWQHPKRGVVFPDEFIAVAEHFNLIIPIGEWVLRT
ACRQYVDWKKRYAPFNCTLAINISLHQFQHKGFISSVKHILQEYQMPSDWLELEITEATAVNFLGKIEETLSALRNMGIK
LAFDNFGSGYSFLSHLKNSPIQSIKLKQALIEDAHLRENDNLIIKSTIALSQELGLNVVVGGVETEEQLNFLRSSHCFEV
QGYYSSKPLTVVQMTQFIEERNSKGL
>Mature_506_residues
MIIVVWRLPLSDGNKALFERSYYRERKAREEAELLLENKTRELHLLNQDLEKKNAELIKTLKDLERVQKKLSKLAHFDVL
SRLPNRLQFELDLKREIARSKRYGRHLALLSIDLDFFKNVNDRFGHDVGDGLLREVAKRLCSSLREEDCVARLGGDEFAV
ILTEINNPQQAKLVANNMIQKMGKPFHIKGHTVMIGISIGIAYFPDAGDEAITLRKNADIALYNAKECGRNNCQIFTPSL
RKQYSKRLGIGTELHLALERQEFFLVYQPRVDLKTNTMVGMEVLLRWQHPKRGVVFPDEFIAVAEHFNLIIPIGEWVLRT
ACRQYVDWKKRYAPFNCTLAINISLHQFQHKGFISSVKHILQEYQMPSDWLELEITEATAVNFLGKIEETLSALRNMGIK
LAFDNFGSGYSFLSHLKNSPIQSIKLKQALIEDAHLRENDNLIIKSTIALSQELGLNVVVGGVETEEQLNFLRSSHCFEV
QGYYSSKPLTVVQMTQFIEERNSKGL

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=435, Percent_Identity=33.1034482758621, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=29.3577981651376, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI226510982, Length=416, Percent_Identity=29.0865384615385, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=30.3149606299213, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1788502, Length=258, Percent_Identity=28.6821705426357, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI87081845, Length=242, Percent_Identity=29.7520661157025, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=30.8, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788381, Length=221, Percent_Identity=33.4841628959276, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=30, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787055, Length=245, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=38.1818181818182, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=32.0224719101124, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788849, Length=438, Percent_Identity=24.2009132420091, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082007, Length=176, Percent_Identity=34.0909090909091, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87081743, Length=233, Percent_Identity=26.6094420600858, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787802, Length=177, Percent_Identity=29.9435028248588, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787262, Length=173, Percent_Identity=34.6820809248555, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=34.4444444444444, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788956, Length=180, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081977, Length=181, Percent_Identity=28.7292817679558, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788085, Length=107, Percent_Identity=34.5794392523364, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082096, Length=421, Percent_Identity=20.9026128266033, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081974, Length=162, Percent_Identity=29.0123456790123, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787056, Length=160, Percent_Identity=33.75, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 58169; Mature: 58169

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3 ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVVWRLPLSDGNKALFERSYYRERKAREEAELLLENKTRELHLLNQDLEKKNAELIKT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHH
LKDLERVQKKLSKLAHFDVLSRLPNRLQFELDLKREIARSKRYGRHLALLSIDLDFFKNV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCEEEEEEEEHHHHHCC
NDRFGHDVGDGLLREVAKRLCSSLREEDCVARLGGDEFAVILTEINNPQQAKLVANNMIQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHH
KMGKPFHIKGHTVMIGISIGIAYFPDAGDEAITLRKNADIALYNAKECGRNNCQIFTPSL
HCCCCEEECCCEEEEEEEEEEEECCCCCCCEEEEECCCCEEEEEHHHCCCCCCEEECHHH
RKQYSKRLGIGTELHLALERQEFFLVYQPRVDLKTNTMVGMEVLLRWQHPKRGVVFPDEF
HHHHHHHCCCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHEECCCCCCCCCCHHH
IAVAEHFNLIIPIGEWVLRTACRQYVDWKKRYAPFNCTLAINISLHQFQHKGFISSVKHI
HHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHCCHHHHHHHH
LQEYQMPSDWLELEITEATAVNFLGKIEETLSALRNMGIKLAFDNFGSGYSFLSHLKNSP
HHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCC
IQSIKLKQALIEDAHLRENDNLIIKSTIALSQELGLNVVVGGVETEEQLNFLRSSHCFEV
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
QGYYSSKPLTVVQMTQFIEERNSKGL
ECEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIVVWRLPLSDGNKALFERSYYRERKAREEAELLLENKTRELHLLNQDLEKKNAELIKT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHH
LKDLERVQKKLSKLAHFDVLSRLPNRLQFELDLKREIARSKRYGRHLALLSIDLDFFKNV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCEEEEEEEEHHHHHCC
NDRFGHDVGDGLLREVAKRLCSSLREEDCVARLGGDEFAVILTEINNPQQAKLVANNMIQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHH
KMGKPFHIKGHTVMIGISIGIAYFPDAGDEAITLRKNADIALYNAKECGRNNCQIFTPSL
HCCCCEEECCCEEEEEEEEEEEECCCCCCCEEEEECCCCEEEEEHHHCCCCCCEEECHHH
RKQYSKRLGIGTELHLALERQEFFLVYQPRVDLKTNTMVGMEVLLRWQHPKRGVVFPDEF
HHHHHHHCCCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHEECCCCCCCCCCHHH
IAVAEHFNLIIPIGEWVLRTACRQYVDWKKRYAPFNCTLAINISLHQFQHKGFISSVKHI
HHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEHHHHHHCCHHHHHHHH
LQEYQMPSDWLELEITEATAVNFLGKIEETLSALRNMGIKLAFDNFGSGYSFLSHLKNSP
HHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCCC
IQSIKLKQALIEDAHLRENDNLIIKSTIALSQELGLNVVVGGVETEEQLNFLRSSHCFEV
HHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEE
QGYYSSKPLTVVQMTQFIEERNSKGL
ECEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]