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The map label for this gene is 54293958

Identifier: 54293958

GI number: 54293958

Start: 1147633

End: 1149258

Strand: Reverse

Name: 54293958

Synonym: lpl1015

Alternate gene names: NA

Gene position: 1149258-1147633 (Counterclockwise)

Preceding gene: 54293959

Following gene: 54293957

Centisome position: 34.35

GC content: 29.03

Gene sequence:

>1626_bases
ATGGAGCAAACAATTAATAAAAATTTCAATTCCTTAGATACACTGGTAAGTTTATTTGGTATTAACTACTCTAATTTAGC
AAAGTTAATTTACCCCACTACAAATAACTTATATCACAGTTTTTCAATTCCCAAAAAATCAGGTGAGTTAAGAGAAATAA
ATGCCCCAAATCGCATATTAAAAGAAATTCAGTATAAATTATTAAATGAGTTGCAATCATATTACTCTAAAAGAAATTGC
ACTCATGGTTTTATAAACGAAAGAAATGTCGTAACCAACGCACGTCCTCACGTTAAGAAAAATATCATCCTTAATTTAGA
TTTAAAAGAATTCTTTCAATCCATTCATTTTGGAAGAGTCCGAAATTTATTTATGAGTAATCCTTTTAATTTTAATAAAA
ATGTGGCAACAGTTTTAGCTCAAATTTGTTGTCATAAAGGTCATCTTCCACAAGGTGCTCCGACATCACCACTCATAACT
AATTTAATTTGTTATAAATTAGATAAAGAATTAAGTAAACTAGCTTTCAATAATAACTGCACTGTTACAAGGTATGTTGA
TGATATTACTTTTTCCTTTAATTGTTCACATGATAAAATACCCCGAGACATTCTAGATGGGATTAGTGGTGAATCAATTA
GTATATCTAAAAAACTAGTTAACATTATAAATAAAAACGGTTTTGAGATTAATTATAAAAAAGTCCGTCTGTCAAGCTCA
AACCAAAGACAGCAAGTTACAGGTATAGTTACAAATGTGAAAGTTAATTTGCCTCGAAAATATATAAAAAAAACTCAATC
AATGTTATATGCCTGGAAAAATTTCTCCCTACCCAATGCCGAACAAGCACATATCAATAATTATCTAGAAAAGCCTTATA
AATATCAAAGGTTCATTAGATATAATAAAGACAAAAGTTATTTTAATTTAATGATTAAAGGAAGAATTAATTATATCGGT
ATGGTACGAGGTCAATCTGATTGTATTTATAGAAAACTTCTCTATCAATATACTGAATTAATAGGCAATCCGAATAAAGA
GCTATTAAAATCAGTAGATGATTGTTTAGCTGACAGTGTATTTATCACAGAATATCCTATTGAATCTAAACAAGGCACTG
CCTTCTTTCTAAAAGATATAGGATTAGTTACTGCAGCTCACGTTGTTGAAGGAATTCATGAAACTAATAGTTGTTTTTTA
GATTTTTTCCGACATTATGAGGTTAAAATTAAAAGAAAAGCTACGTTATTTAAGAAAAGTGAGGAAAAAGATATTGCAAT
TTTTTATGTAGGGGACGACTTTAAAAATCTCCCTTCCTTAAAAGTAGGGGATGATTCAAAATTAGCGATTGGTGACCAGA
TTAAACTTATAGGATTTCCTGATTATAATTATCATGATAGTTACTTATCTAATTTGGGGAAAATAATCCAGAAAAAAACA
ATGTATAATCTTGATGTCTGGATAGTTGATTTACCTATAAATTTTGGTGTTAGTGGTGGGCCAGTTTTTAATAACAAAAA
TGAAGTTATAGGAGTTGCATTGCAAGGCTCAAAAAAACATGATCAATCAACTTACTCACACTATTTTGTTCCAATTTCAA
AAGTAATTGAGATGGCGCAAAATTAA

Upstream 100 bases:

>100_bases
GGTTATAAGTATGTTATCTATTACGCTCAGTATTATTACTAAACTGTTATTGCAGCTAAGGGTATAAGAAAAATTCTACC
GCCAATTATATGGAGTGGGG

Downstream 100 bases:

>100_bases
TTTGGTTCTGCGTCACTGCAAATTTCCCAGCAGTGACGCAGAAAAATCACCTTGATTTTACCGCGTAAAATCAACACATT
TCAGAATTTTGTCCGATCCC

Product: hypothetical protein

Products: NA

Alternate protein names: ORF4-EC67 RT; RNA-directed DNA polymerase; Reverse transcriptase; Ribonuclease H; RNase H [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MEQTINKNFNSLDTLVSLFGINYSNLAKLIYPTTNNLYHSFSIPKKSGELREINAPNRILKEIQYKLLNELQSYYSKRNC
THGFINERNVVTNARPHVKKNIILNLDLKEFFQSIHFGRVRNLFMSNPFNFNKNVATVLAQICCHKGHLPQGAPTSPLIT
NLICYKLDKELSKLAFNNNCTVTRYVDDITFSFNCSHDKIPRDILDGISGESISISKKLVNIINKNGFEINYKKVRLSSS
NQRQQVTGIVTNVKVNLPRKYIKKTQSMLYAWKNFSLPNAEQAHINNYLEKPYKYQRFIRYNKDKSYFNLMIKGRINYIG
MVRGQSDCIYRKLLYQYTELIGNPNKELLKSVDDCLADSVFITEYPIESKQGTAFFLKDIGLVTAAHVVEGIHETNSCFL
DFFRHYEVKIKRKATLFKKSEEKDIAIFYVGDDFKNLPSLKVGDDSKLAIGDQIKLIGFPDYNYHDSYLSNLGKIIQKKT
MYNLDVWIVDLPINFGVSGGPVFNNKNEVIGVALQGSKKHDQSTYSHYFVPISKVIEMAQN

Sequences:

>Translated_541_residues
MEQTINKNFNSLDTLVSLFGINYSNLAKLIYPTTNNLYHSFSIPKKSGELREINAPNRILKEIQYKLLNELQSYYSKRNC
THGFINERNVVTNARPHVKKNIILNLDLKEFFQSIHFGRVRNLFMSNPFNFNKNVATVLAQICCHKGHLPQGAPTSPLIT
NLICYKLDKELSKLAFNNNCTVTRYVDDITFSFNCSHDKIPRDILDGISGESISISKKLVNIINKNGFEINYKKVRLSSS
NQRQQVTGIVTNVKVNLPRKYIKKTQSMLYAWKNFSLPNAEQAHINNYLEKPYKYQRFIRYNKDKSYFNLMIKGRINYIG
MVRGQSDCIYRKLLYQYTELIGNPNKELLKSVDDCLADSVFITEYPIESKQGTAFFLKDIGLVTAAHVVEGIHETNSCFL
DFFRHYEVKIKRKATLFKKSEEKDIAIFYVGDDFKNLPSLKVGDDSKLAIGDQIKLIGFPDYNYHDSYLSNLGKIIQKKT
MYNLDVWIVDLPINFGVSGGPVFNNKNEVIGVALQGSKKHDQSTYSHYFVPISKVIEMAQN
>Mature_541_residues
MEQTINKNFNSLDTLVSLFGINYSNLAKLIYPTTNNLYHSFSIPKKSGELREINAPNRILKEIQYKLLNELQSYYSKRNC
THGFINERNVVTNARPHVKKNIILNLDLKEFFQSIHFGRVRNLFMSNPFNFNKNVATVLAQICCHKGHLPQGAPTSPLIT
NLICYKLDKELSKLAFNNNCTVTRYVDDITFSFNCSHDKIPRDILDGISGESISISKKLVNIINKNGFEINYKKVRLSSS
NQRQQVTGIVTNVKVNLPRKYIKKTQSMLYAWKNFSLPNAEQAHINNYLEKPYKYQRFIRYNKDKSYFNLMIKGRINYIG
MVRGQSDCIYRKLLYQYTELIGNPNKELLKSVDDCLADSVFITEYPIESKQGTAFFLKDIGLVTAAHVVEGIHETNSCFL
DFFRHYEVKIKRKATLFKKSEEKDIAIFYVGDDFKNLPSLKVGDDSKLAIGDQIKLIGFPDYNYHDSYLSNLGKIIQKKT
MYNLDVWIVDLPINFGVSGGPVFNNKNEVIGVALQGSKKHDQSTYSHYFVPISKVIEMAQN

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49; =3.1.26.4 [H]

Molecular weight: Translated: 62243; Mature: 62243

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTINKNFNSLDTLVSLFGINYSNLAKLIYPTTNNLYHSFSIPKKSGELREINAPNRIL
CCCCCCCCCHHHHHHHHHHCCCHHHHEEEEECCCCCEEEEECCCCCCCCCEECCCHHHHH
KEIQYKLLNELQSYYSKRNCTHGFINERNVVTNARPHVKKNIILNLDLKEFFQSIHFGRV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCEEEEECHHHHHHHHHHHHH
RNLFMSNPFNFNKNVATVLAQICCHKGHLPQGAPTSPLITNLICYKLDKELSKLAFNNNC
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TVTRYVDDITFSFNCSHDKIPRDILDGISGESISISKKLVNIINKNGFEINYKKVRLSSS
EEEEEEECEEEEEECCCCCCCHHHHCCCCCCCEEHHHHHHHHHCCCCCEEEEEEEEECCC
NQRQQVTGIVTNVKVNLPRKYIKKTQSMLYAWKNFSLPNAEQAHINNYLEKPYKYQRFIR
CCHHHHEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHH
YNKDKSYFNLMIKGRINYIGMVRGQSDCIYRKLLYQYTELIGNPNKELLKSVDDCLADSV
CCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCE
FITEYPIESKQGTAFFLKDIGLVTAAHVVEGIHETNSCFLDFFRHYEVKIKRKATLFKKS
EEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHCC
EEKDIAIFYVGDDFKNLPSLKVGDDSKLAIGDQIKLIGFPDYNYHDSYLSNLGKIIQKKT
CCCCEEEEEECCCCCCCCCCEECCCCCEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHH
MYNLDVWIVDLPINFGVSGGPVFNNKNEVIGVALQGSKKHDQSTYSHYFVPISKVIEMAQ
EEEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHEEEEEHHHHHHHHC
N
C
>Mature Secondary Structure
MEQTINKNFNSLDTLVSLFGINYSNLAKLIYPTTNNLYHSFSIPKKSGELREINAPNRIL
CCCCCCCCCHHHHHHHHHHCCCHHHHEEEEECCCCCEEEEECCCCCCCCCEECCCHHHHH
KEIQYKLLNELQSYYSKRNCTHGFINERNVVTNARPHVKKNIILNLDLKEFFQSIHFGRV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCEEEEECHHHHHHHHHHHHH
RNLFMSNPFNFNKNVATVLAQICCHKGHLPQGAPTSPLITNLICYKLDKELSKLAFNNNC
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TVTRYVDDITFSFNCSHDKIPRDILDGISGESISISKKLVNIINKNGFEINYKKVRLSSS
EEEEEEECEEEEEECCCCCCCHHHHCCCCCCCEEHHHHHHHHHCCCCCEEEEEEEEECCC
NQRQQVTGIVTNVKVNLPRKYIKKTQSMLYAWKNFSLPNAEQAHINNYLEKPYKYQRFIR
CCHHHHEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHH
YNKDKSYFNLMIKGRINYIGMVRGQSDCIYRKLLYQYTELIGNPNKELLKSVDDCLADSV
CCCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCE
FITEYPIESKQGTAFFLKDIGLVTAAHVVEGIHETNSCFLDFFRHYEVKIKRKATLFKKS
EEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHCC
EEKDIAIFYVGDDFKNLPSLKVGDDSKLAIGDQIKLIGFPDYNYHDSYLSNLGKIIQKKT
CCCCEEEEEECCCCCCCCCCEECCCCCEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHH
MYNLDVWIVDLPINFGVSGGPVFNNKNEVIGVALQGSKKHDQSTYSHYFVPISKVIEMAQ
EEEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHEEEEEHHHHHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2466332; 1701261; 1722556 [H]