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The map label for this gene is aroB [H]

Identifier: 54293908

GI number: 54293908

Start: 1078336

End: 1079445

Strand: Direct

Name: aroB [H]

Synonym: lpl0964

Alternate gene names: 54293908

Gene position: 1078336-1079445 (Clockwise)

Preceding gene: 54293907

Following gene: 54293909

Centisome position: 32.23

GC content: 38.47

Gene sequence:

>1110_bases
ATGGCGAAGTTTGAACTTTATGCCGAGGTTGATGTTTCGATTTCAGGGCATCAATATCCAGTAATTATTTGCCGCAATGG
TTTAATTGATCCTGAATTAATTAATCGTTTTATCACTTCAAAACAGGTGCTTATTGTTACTAATCGAACAGTGGCACCTT
TGTACCTAGGCCATTTGCAATCTGTTTTACCATCAAAGCAATGCGATGTTGTTATTCTGGAAGACGGTGAAGAGCATAAA
AATCAGCGCAGTTTATCTACTATTTATGATTCTTTGATTCAAAACAAACATCATAGAGATACCTCAATCATCGCTTTGGG
TGGGGGAGTGATTGGTGATATGGCTGGTTTTGCAGCTTCTACGTACCAACGAGGAGTGCGATTTATTCAGCTGCCTACTA
CGTTACTGGCTCAGGTTGATGCTTCAGTTGGTGGTAAAACAGCGATTAATCATCCTGCCGGTAAAAATATGATTGGCAGT
TTTTACCAACCTCAAGCGGTCATAATTGATTTAAATACCTTAAAAACATTACCTGAGCGTGAGTTTCGTGCAGGTATTGC
CGAGATGATTAAATACGCTTTGTTGGTTGGTGGCTCTTTTTTTGAACGAATTCAAGCGGTTCTGCAACAAGGATTAACGG
TACATAGCCCGGAGTTACCACTACTGATAGCAGAATGTTGTCAAGTTAAAGCTAAAATTGTAGAGCAAGATGAAAGGGAA
TCCGGGGTGCGTGCTTTGCTTAATCTGGGGCATACTTTTGCTCATGCGCTGGAAACGTATACCGATTATAAAAAGTGGTT
ACATGGAGAAGCCGTTGCCATAGGTTTATATTGTGCGGCTGTATTATCAGAGAAGAAGGGCTTGCTGGATAAACCAATTG
TAGACCAGGTAGAAAAGATGCTCATACATGCTGGTTTGCCTCATAAAATTCCAAATTCAATAGATTTAATTCAATTAAGA
GAGTTGATGAGTTTGGATAAGAAAATTAAAAATAATTGTTTACGTTTCGTAATGATTAAAAAACCAGGTGCTTGTTATAT
TGATGACTCAGTTACTGAAGATTGTTTGCACAATACACTGATTAATGTGGTAGAAGGAGAACAAAAATGA

Upstream 100 bases:

>100_bases
GATGAGCGAGAACCTTTTTATGATGAATTGGCAGATGTCAGTTTTGAAACAGATAAATTGACTGTAAAAGCTGTTGCAAA
CAATATAATAAAATACTTAT

Downstream 100 bases:

>100_bases
TAGATGGAAAGGAGCCTCTTGATGAGGGAGTTGCCAATCAGCCCAGAACTCTATTCAAACCAGGAGCCTGGCTTGCGAAA
GTTGATTTCATTAATCATTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MAKFELYAEVDVSISGHQYPVIICRNGLIDPELINRFITSKQVLIVTNRTVAPLYLGHLQSVLPSKQCDVVILEDGEEHK
NQRSLSTIYDSLIQNKHHRDTSIIALGGGVIGDMAGFAASTYQRGVRFIQLPTTLLAQVDASVGGKTAINHPAGKNMIGS
FYQPQAVIIDLNTLKTLPEREFRAGIAEMIKYALLVGGSFFERIQAVLQQGLTVHSPELPLLIAECCQVKAKIVEQDERE
SGVRALLNLGHTFAHALETYTDYKKWLHGEAVAIGLYCAAVLSEKKGLLDKPIVDQVEKMLIHAGLPHKIPNSIDLIQLR
ELMSLDKKIKNNCLRFVMIKKPGACYIDDSVTEDCLHNTLINVVEGEQK

Sequences:

>Translated_369_residues
MAKFELYAEVDVSISGHQYPVIICRNGLIDPELINRFITSKQVLIVTNRTVAPLYLGHLQSVLPSKQCDVVILEDGEEHK
NQRSLSTIYDSLIQNKHHRDTSIIALGGGVIGDMAGFAASTYQRGVRFIQLPTTLLAQVDASVGGKTAINHPAGKNMIGS
FYQPQAVIIDLNTLKTLPEREFRAGIAEMIKYALLVGGSFFERIQAVLQQGLTVHSPELPLLIAECCQVKAKIVEQDERE
SGVRALLNLGHTFAHALETYTDYKKWLHGEAVAIGLYCAAVLSEKKGLLDKPIVDQVEKMLIHAGLPHKIPNSIDLIQLR
ELMSLDKKIKNNCLRFVMIKKPGACYIDDSVTEDCLHNTLINVVEGEQK
>Mature_368_residues
AKFELYAEVDVSISGHQYPVIICRNGLIDPELINRFITSKQVLIVTNRTVAPLYLGHLQSVLPSKQCDVVILEDGEEHKN
QRSLSTIYDSLIQNKHHRDTSIIALGGGVIGDMAGFAASTYQRGVRFIQLPTTLLAQVDASVGGKTAINHPAGKNMIGSF
YQPQAVIIDLNTLKTLPEREFRAGIAEMIKYALLVGGSFFERIQAVLQQGLTVHSPELPLLIAECCQVKAKIVEQDERES
GVRALLNLGHTFAHALETYTDYKKWLHGEAVAIGLYCAAVLSEKKGLLDKPIVDQVEKMLIHAGLPHKIPNSIDLIQLRE
LMSLDKKIKNNCLRFVMIKKPGACYIDDSVTEDCLHNTLINVVEGEQK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=353, Percent_Identity=44.7592067988669, Blast_Score=307, Evalue=7e-85,
Organism=Saccharomyces cerevisiae, GI6320332, Length=349, Percent_Identity=36.3896848137536, Blast_Score=196, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40845; Mature: 40714

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFELYAEVDVSISGHQYPVIICRNGLIDPELINRFITSKQVLIVTNRTVAPLYLGHLQ
CCCEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
SVLPSKQCDVVILEDGEEHKNQRSLSTIYDSLIQNKHHRDTSIIALGGGVIGDMAGFAAS
HHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHH
TYQRGVRFIQLPTTLLAQVDASVGGKTAINHPAGKNMIGSFYQPQAVIIDLNTLKTLPER
HHHCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCEEEEECHHHHCCCCH
EFRAGIAEMIKYALLVGGSFFERIQAVLQQGLTVHSPELPLLIAECCQVKAKIVEQDERE
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHH
SGVRALLNLGHTFAHALETYTDYKKWLHGEAVAIGLYCAAVLSEKKGLLDKPIVDQVEKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LIHAGLPHKIPNSIDLIQLRELMSLDKKIKNNCLRFVMIKKPGACYIDDSVTEDCLHNTL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCHHHHHHHHHHH
INVVEGEQK
HHHHCCCCC
>Mature Secondary Structure 
AKFELYAEVDVSISGHQYPVIICRNGLIDPELINRFITSKQVLIVTNRTVAPLYLGHLQ
CCEEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
SVLPSKQCDVVILEDGEEHKNQRSLSTIYDSLIQNKHHRDTSIIALGGGVIGDMAGFAAS
HHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHH
TYQRGVRFIQLPTTLLAQVDASVGGKTAINHPAGKNMIGSFYQPQAVIIDLNTLKTLPER
HHHCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCEEEEECHHHHCCCCH
EFRAGIAEMIKYALLVGGSFFERIQAVLQQGLTVHSPELPLLIAECCQVKAKIVEQDERE
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHH
SGVRALLNLGHTFAHALETYTDYKKWLHGEAVAIGLYCAAVLSEKKGLLDKPIVDQVEKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LIHAGLPHKIPNSIDLIQLRELMSLDKKIKNNCLRFVMIKKPGACYIDDSVTEDCLHNTL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCHHHHHHHHHHH
INVVEGEQK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA