Click here to switch to the map view.

The map label for this gene is pilQ [H]

Identifier: 54293906

GI number: 54293906

Start: 1075280

End: 1077376

Strand: Direct

Name: pilQ [H]

Synonym: lpl0962

Alternate gene names: 54293906

Gene position: 1075280-1077376 (Clockwise)

Preceding gene: 54293905

Following gene: 54293907

Centisome position: 32.14

GC content: 38.96

Gene sequence:

>2097_bases
GTGAGAAAAATTATCGCGATTTTGATATTAATTAGTGCCAGTTTGAGTATGGCATATTCTAAAGATAATTCGCTCATTTC
AGTAAAAGTATTGCCATTGCCCGAAAACAGAGTGCGTATTGATTTTCAATTTTCCAAGCCCTTAAAGCAGTTGCCTGCAA
GCTTTATTACTCAAAAGCCGCCCCGTTTGGTGTTAGATTTTATCAGCACTGATATGCAAATTCCTTCGGATCAGAAAACT
AAAACTATTCAATTAGGCTCATTACACAGTTATAACATTGTTGCTGTTGGGGATAGAGTAAGGGCCATATTGGAACTGGA
TCGTTCAGTATCCTATTCTGGCAGTACGGCGGGTTCCGTTTATAGCCTTGTCCTGAATGGTAAAAGCAATGATTTATTTG
AAAATAGCAAGGAGGTATTCATAACGAACCAGGTTGTGAACGCCAAGCATGAAATTAAAAGAATTGATTTTCGTGGTATA
GAAAAGCAGGGCGGTAGAGTTTTAATTGATGTTTCTGATACGGGTATTCCAATTGATGTAACTCAAGTTGGGAAAGAAAT
AGTCGTTAATTTCCTGAATACCAAGATCCCTTTGAATTTAATGAAACGGTATGATGTTTCTGATTTTCACAGCCCTGTGC
AGATTATTACGATGCAACAGGAAGGCAAAAAGGTTCGCATGACCATCCTCAGCAAAGGGGATTATGGACATTTTGTTTAT
CAGGTCAATAAACAATTTATGGTCGATGTCTTTCCTTTAACTGCGGAAGAAATTCGTCAGGCGAAATTGAAGAAACAGGT
ATTTACTGGCAAACGTATTTCTTTAAATTTCCAGAATATTAGTATTCGAGCTGTACTTCAATTGCTGGCAGATTTTACTG
GAATCAATATGGTTGTCAGCGACAAAGTACAAGGAGATATTACGCTTAGATTAAATGATATCCCCTGGGATCAGGCTCTG
GATATCATTTTAACCACACAAGGGCTAGATAAGCGCAGAAAGGGCAACGTCATGTTGATAGATACCAAGGCCTCCATGGA
TAAAATGGAGGAAGAACAGCTCAAAAGTCAACAGACAATTGAAAAACTTGAGCCTATCCGTTCTGATTTAATACAAATTA
ATTATGCAAAGGCAGCAGATATTGCTGTTTTGATCAAGGATAAGCAAAATTCCCTATTATCAGACAGGGGAAAAATAAGT
GTTGATGCCAGAACGAATACAATCTGGATTCAGGATACTGGCACCAAAATTGAGGAAGTAAGGGAACTGATAAAGCAATT
GGATATCCCCGTTAAGCAAGTGCTTATTGAGGCAAGAATTGTTGAAGTGACTAAAGATTTTAGCCAGGATATTGGGATAC
GCTGGGGAGTATCAAGACCAACTCACTTAAGTGGTACACTGGAAGGTGCTAACGAGTTAGCGAGAGGCACAGCACCAGCC
AATGTTGTCCCCTTGGAAAGAAGATTAAATCTTGATTTGGCAGCCGCTCCTTTAACCGGAGCTACACCGGCCTCGGTAGG
TATTGCGCTAGCTAAACTTAATGATAACATTCTGCTTGATCTGGAATTGTCTGCTTTGGAAAGCGAAGGGCGTGCTGAAT
TAATATCCAGTCCTCGCTTGATTACTACGAATCAACAGGCAGCAGTCATAGAGTCTGGTGAGGAGATTCCCTATCAGGAG
GCAACATCAAGTGGAGCGACTGCTGTTGCATTTAAAAAAGCGGTATTGAGTTTGAAAGTTACCCCGCAAATTACGCCTGA
TGGCAAAATTTTGATGGATTTACAGATAAATCAGGATACTCCTTCCCCACAAACATTCCTTGGTGTTCCAGCAATAATAA
CAAAGGAGATTCAGACGAATGTTCTGGTTAATAATGGACAAACCATAGTACTTGGGGGTATTTATAAGCAAGATAAGAAC
AAGGTAATCAATAGAATTCCTTTCTTTGGTGAGTTGCCTGTTGTCGGTATTTTATTTAGTAATAGACAAATCACATTGAA
AAATGAAGAATTACTTATCTTTATTACACCAAGAATAATAACGAATGCCTTATCGATTACAACGATAGAGGGACGCGAGA
AAGATGTTTATAAATAA

Upstream 100 bases:

>100_bases
AAATGATCTCATTAAATTGGAAGAAACTGTACAGAAATCAGGAACGTGGGAAAAACAGTCCACCACAATTAATTTGGATA
CTGGCAAGCAGGAGTGAGGC

Downstream 100 bases:

>100_bases
TCAAGATTGGACTAATTTTATCTCATTAATAAAGATAAAAAACATTAATTTAATAGAAGTGCCTCAACACGGTGAACATG
TTATAATTAAAATATAGCCC

Product: type IV pilus (Tfp) assembly protein PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRKIIAILILISASLSMAYSKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Sequences:

>Translated_698_residues
MRKIIAILILISASLSMAYSKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK
>Mature_698_residues
MRKIIAILILISASLSMAYSKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=420, Percent_Identity=33.3333333333333, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI87082242, Length=364, Percent_Identity=25.8241758241758, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 77475; Mature: 77475

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIAILILISASLSMAYSKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKP
CHHHHHHHHHHHHHHEEEECCCCCEEEEEEEECCCCCEEEEEEECCHHHHCCHHHHCCCC
PRLVLDFISTDMQIPSDQKTKTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSV
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEE
YSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGIEKQGGRVLIDVSDTGIPIDV
EEEEEECCCCCCCCCCCEEEEEEEHHCCHHHHEECCCCCCCCCCCEEEEEECCCCCEEEH
TQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEE
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVS
EECCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCEEHHHHHHHHHCCCCCEEEEE
DKVQGDITLRLNDIPWDQALDIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTI
CCCCCEEEEEEECCCHHHCEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKISVDARTNTIWIQDTGTKIEEV
HHHHHHHHHHEEEEECCCCCEEEEEECCCCCHHCCCCCEEEEECCCEEEEEECCCHHHHH
RELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCCC
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRL
CEEEHHHHCCCEEEECCCCCCCCHHHCEEEEEECCCEEEEEEEHHCCCCCCHHHHCCCEE
ITTNQQAAVIESGEEIPYQEATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDT
EECCCCEEEEECCCCCCCHHCCCCCCCHHEEEEEEEEEEECCEECCCCCEEEEEEECCCC
PSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKNKVINRIPFFGELPVVGILFS
CCCCEEECCCHHEECCCEEEEEEECCCEEEEEEEEECCHHHHHHHCCCCCCCCEEEEEEC
NRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK
CCEEEEECCEEEEEECHHHHHCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MRKIIAILILISASLSMAYSKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKP
CHHHHHHHHHHHHHHEEEECCCCCEEEEEEEECCCCCEEEEEEECCHHHHCCHHHHCCCC
PRLVLDFISTDMQIPSDQKTKTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSV
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCEE
YSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGIEKQGGRVLIDVSDTGIPIDV
EEEEEECCCCCCCCCCCEEEEEEEHHCCHHHHEECCCCCCCCCCCEEEEEECCCCCEEEH
TQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEE
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVS
EECCEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCEEHHHHHHHHHCCCCCEEEEE
DKVQGDITLRLNDIPWDQALDIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTI
CCCCCEEEEEEECCCHHHCEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
EKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKISVDARTNTIWIQDTGTKIEEV
HHHHHHHHHHEEEEECCCCCEEEEEECCCCCHHCCCCCEEEEECCCEEEEEECCCHHHHH
RELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHCCCCCC
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRL
CEEEHHHHCCCEEEECCCCCCCCHHHCEEEEEECCCEEEEEEEHHCCCCCCHHHHCCCEE
ITTNQQAAVIESGEEIPYQEATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDT
EECCCCEEEEECCCCCCCHHCCCCCCCHHEEEEEEEEEEECCEECCCCCEEEEEEECCCC
PSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKNKVINRIPFFGELPVVGILFS
CCCCEEECCCHHEECCCEEEEEEECCCEEEEEEEEECCHHHHHHHCCCCCCCCEEEEEEC
NRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK
CCEEEEECCEEEEEECHHHHHCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]