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The map label for this gene is recQ [H]

Identifier: 54293843

GI number: 54293843

Start: 1008870

End: 1010696

Strand: Reverse

Name: recQ [H]

Synonym: lpl0899

Alternate gene names: 54293843

Gene position: 1010696-1008870 (Counterclockwise)

Preceding gene: 54293847

Following gene: 54293842

Centisome position: 30.21

GC content: 39.46

Gene sequence:

>1827_bases
ATGGGAACTTTAGCGCAACCATCTTTTATAAATCCAAACGCATTGGCTGTTTTAAAAAAATATTTTGGATTTGATTCCTT
CAGATCTCCTCAGGAAAAAATAATTGAGGATGTCATTTCTGGGGAAGACGTACTGGTTTTGATGCCTACTGGAGGGGGAA
AATCGCTATGCTATCAAATTCCAGCCATTGTCCGCCCTGGTGTTGGCATTGTAGTATCTCCTTTAATCGCGTTAATGGAA
GATCAAGTAACCGCTCTCAAACTACAGGGCATTCGTGCGGCTTACTACAACTCATCCTTAACCGCAGAAGAGGCTAGAAA
TGTATTAAATCAATTACATCATAATGAATTGGATTTACTCTATATTGCTCCAGAACGTCTTATTAGCACCTCGTTTCTGG
ATCGACTGTCAGAATGTACTATCTCTTTATTTGCTATCGATGAAGCACACTGTATTTCACAATGGGGACATGATTTTCGA
CCTGAATACGCCTGTTTAGGTTTACTGAAAACTAACTTTCCTGACATTCCTATGATTGCTCTGACAGCTACTGCCGATAA
GCAAACACGTGAGGATATTGTTACCAAGTTGAATTATCAACCCAAAAAATACGTTGTTTCATTCAATCGACCGAATATCC
ATTACAAAGTAGTTCCTAAAACAAATGCAGTGAAGCAATTAAATCTGTTTTTACAATCTGATACCCAGCAATCTGGAATT
ATTTATTGTGGAACCCGCCATACAGTCGAACATCTTACAGCGAAATTACAAGAACTTGGATTTAAAGCACGCGCTTATCA
TGCAGGCCTGCCTCATGCGGATCGGCGTGAGGTGCAGAACCTTTTCAGATACGATCGCATTGATATTGTGGTAGCTACTA
TTGCTTTTGGAATGGGTATTGACAAGCCTAATGTTCGCTTTGTTGTTCACCATGATTTACCCAAAAGCATTGAAGGTTAC
TACCAGGAAACAGGTCGTGCAGGACGTGACGGATTACCGGCCAAGGCCCTTCTTCTTTATGATGCTGCGGATAGTGCCCG
TTTACGGTCCTGGATCATGAACATTCCTCTTGATGAGCAAAGACATATAGAAACCAATAAATTAAATCATATGCTTGCTT
TTGCTGAAGCGTCGCATTGTCGTCGTCAAATTTTATTACGCTATTTTGATGAACCTTCTCATACAGAATGTAAAAACTGT
GATGTCTGCGATAACCCACCGCAGACAGCCGATGCAACAGAAGATGCGCAAAAATTTTTATCGTGTATTTATCGATTAAA
ACAAAGCTATGGTTTAACTCATACTATTGATGTCCTGAGAGGTAGTTTATCTGAAAAAATCAAGCAGTCTGGGCATGAGC
ATTTAAGTACCTTTGGAATTGGGAAGGAGAAATCTGCCAATTATTGGAAGCATCTTGCCTGGCAATTAATTCATAAGGAT
TATTGTTTACAGGATATGAATCATTTTAATGTGTTACGCTTGACCCCAAAAGCGATTCCCCTCCTAAAAGGTGAAGAGAG
TATTTCATTAACCATTCCTAACAATGACCTGAATAGCAGTAAAGAGAAAGGCAAGCAGAATCCTTCCTTTAAACCTGAAA
GTAACCCGTTATTTGAAAAGCTTCGTTCGTTAAGACGTCAGTTAGCCGATGAAGAAAACAAACCACCATTTATGATATTC
AGTGATGCTACATTACATGAAATGGCCCAATCAAAACCCAAAAACAGTAAGCAACTACTGAATGTATCTGGGGTTGGGCA
ACATAAATTAGCTCGTTATGGCCATTATTTTCTCGAAGCCTTAAACGAATTTTCAGAAGTCGAGTGA

Upstream 100 bases:

>100_bases
ATTTATTGATTTTAGTCATTGGATTTATTTATGACGCTTTCTTAAAAAATGATATTATTGCGAATTTTTAGCGCCCAGGA
AAGATAATAAGAATAATTAC

Downstream 100 bases:

>100_bases
GATTCCGTTATGCGTAAACTACCAAGACCTTTTTACGAACGTGATACCGTTCTGGTTGCAAAAGAACTTTTAGGTAAATA
TTTGGTTCATCATGATGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MGTLAQPSFINPNALAVLKKYFGFDSFRSPQEKIIEDVISGEDVLVLMPTGGGKSLCYQIPAIVRPGVGIVVSPLIALME
DQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLLYIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFR
PEYACLGLLKTNFPDIPMIALTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHADRREVQNLFRYDRIDIVVATIAFGMGIDKPNVRFVVHHDLPKSIEGY
YQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLDEQRHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNC
DVCDNPPQTADATEDAQKFLSCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKEKGKQNPSFKPESNPLFEKLRSLRRQLADEENKPPFMIF
SDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEALNEFSEVE

Sequences:

>Translated_608_residues
MGTLAQPSFINPNALAVLKKYFGFDSFRSPQEKIIEDVISGEDVLVLMPTGGGKSLCYQIPAIVRPGVGIVVSPLIALME
DQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLLYIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFR
PEYACLGLLKTNFPDIPMIALTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHADRREVQNLFRYDRIDIVVATIAFGMGIDKPNVRFVVHHDLPKSIEGY
YQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLDEQRHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNC
DVCDNPPQTADATEDAQKFLSCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKEKGKQNPSFKPESNPLFEKLRSLRRQLADEENKPPFMIF
SDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEALNEFSEVE
>Mature_607_residues
GTLAQPSFINPNALAVLKKYFGFDSFRSPQEKIIEDVISGEDVLVLMPTGGGKSLCYQIPAIVRPGVGIVVSPLIALMED
QVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLLYIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFRP
EYACLGLLKTNFPDIPMIALTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGII
YCGTRHTVEHLTAKLQELGFKARAYHAGLPHADRREVQNLFRYDRIDIVVATIAFGMGIDKPNVRFVVHHDLPKSIEGYY
QETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLDEQRHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNCD
VCDNPPQTADATEDAQKFLSCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKDY
CLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKEKGKQNPSFKPESNPLFEKLRSLRRQLADEENKPPFMIFS
DATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEALNEFSEVE

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=649, Percent_Identity=37.5963020030817, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI110735439, Length=541, Percent_Identity=36.4140480591497, Blast_Score=318, Evalue=1e-86,
Organism=Homo sapiens, GI169218196, Length=509, Percent_Identity=36.9351669941061, Blast_Score=318, Evalue=1e-86,
Organism=Homo sapiens, GI14591902, Length=535, Percent_Identity=36.4485981308411, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI14591904, Length=535, Percent_Identity=36.4485981308411, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI148612816, Length=422, Percent_Identity=41.4691943127962, Blast_Score=298, Evalue=7e-81,
Organism=Homo sapiens, GI51242947, Length=384, Percent_Identity=42.7083333333333, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI51242943, Length=384, Percent_Identity=42.7083333333333, Blast_Score=283, Evalue=4e-76,
Organism=Homo sapiens, GI284005309, Length=338, Percent_Identity=37.2781065088757, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI7661920, Length=341, Percent_Identity=20.8211143695015, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI222352149, Length=372, Percent_Identity=23.6559139784946, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI55749865, Length=340, Percent_Identity=22.0588235294118, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=598, Percent_Identity=48.8294314381271, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI87082221, Length=341, Percent_Identity=21.1143695014663, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787016, Length=341, Percent_Identity=22.2873900293255, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=663, Percent_Identity=33.6349924585219, Blast_Score=332, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI32564293, Length=674, Percent_Identity=32.7893175074184, Blast_Score=327, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI71987997, Length=435, Percent_Identity=40, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI71987993, Length=435, Percent_Identity=40, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI17552866, Length=410, Percent_Identity=36.0975609756098, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17537549, Length=376, Percent_Identity=24.2021276595745, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71995724, Length=353, Percent_Identity=22.3796033994334, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17507121, Length=353, Percent_Identity=22.0963172804533, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=355, Percent_Identity=21.9718309859155, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565321, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115533224, Length=363, Percent_Identity=21.763085399449, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115532546, Length=369, Percent_Identity=22.7642276422764, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555296, Length=185, Percent_Identity=25.9459459459459, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=526, Percent_Identity=39.1634980988593, Blast_Score=353, Evalue=5e-98,
Organism=Saccharomyces cerevisiae, GI6324217, Length=340, Percent_Identity=25, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320224, Length=344, Percent_Identity=23.8372093023256, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320041, Length=344, Percent_Identity=26.1627906976744, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322912, Length=317, Percent_Identity=23.9747634069401, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322323, Length=317, Percent_Identity=23.9747634069401, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6321856, Length=334, Percent_Identity=24.5508982035928, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323021, Length=337, Percent_Identity=22.5519287833828, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321360, Length=331, Percent_Identity=22.9607250755287, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=247, Percent_Identity=26.7206477732794, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325138, Length=103, Percent_Identity=33.9805825242718, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319714, Length=386, Percent_Identity=20.9844559585492, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646066, Length=631, Percent_Identity=34.86529318542, Blast_Score=332, Evalue=5e-91,
Organism=Drosophila melanogaster, GI24664226, Length=438, Percent_Identity=36.7579908675799, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI62472181, Length=438, Percent_Identity=36.7579908675799, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24664230, Length=438, Percent_Identity=36.7579908675799, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21358123, Length=404, Percent_Identity=35.3960396039604, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI28574962, Length=343, Percent_Identity=24.198250728863, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355075, Length=377, Percent_Identity=21.7506631299735, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24645031, Length=115, Percent_Identity=31.304347826087, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583281, Length=325, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583279, Length=325, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI18857967, Length=365, Percent_Identity=23.2876712328767, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68857; Mature: 68725

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTLAQPSFINPNALAVLKKYFGFDSFRSPQEKIIEDVISGEDVLVLMPTGGGKSLCYQI
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHEEC
PAIVRPGVGIVVSPLIALMEDQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLL
CHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCEEE
YIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFRPEYACLGLLKTNFPDIPMIA
EECHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEE
LTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
EEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCCCE
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHADRREVQNLFRYDRIDIVVATIAFGMGI
EEECCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DKPNVRFVVHHDLPKSIEGYYQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLDEQ
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCH
RHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNCDVCDNPPQTADATEDAQKFL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKEKGKQNPSFKPESNPLFEK
HHHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCHHHHH
LRSLRRQLADEENKPPFMIFSDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEA
HHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCCHHEEECCCCCHHHHHHHHHHHHHH
LNEFSEVE
HHHHHCCC
>Mature Secondary Structure 
GTLAQPSFINPNALAVLKKYFGFDSFRSPQEKIIEDVISGEDVLVLMPTGGGKSLCYQI
CCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHEEC
PAIVRPGVGIVVSPLIALMEDQVTALKLQGIRAAYYNSSLTAEEARNVLNQLHHNELDLL
CHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCEEE
YIAPERLISTSFLDRLSECTISLFAIDEAHCISQWGHDFRPEYACLGLLKTNFPDIPMIA
EECHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEE
LTATADKQTREDIVTKLNYQPKKYVVSFNRPNIHYKVVPKTNAVKQLNLFLQSDTQQSGI
EEECCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCCCE
IYCGTRHTVEHLTAKLQELGFKARAYHAGLPHADRREVQNLFRYDRIDIVVATIAFGMGI
EEECCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DKPNVRFVVHHDLPKSIEGYYQETGRAGRDGLPAKALLLYDAADSARLRSWIMNIPLDEQ
CCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCH
RHIETNKLNHMLAFAEASHCRRQILLRYFDEPSHTECKNCDVCDNPPQTADATEDAQKFL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SCIYRLKQSYGLTHTIDVLRGSLSEKIKQSGHEHLSTFGIGKEKSANYWKHLAWQLIHKD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
YCLQDMNHFNVLRLTPKAIPLLKGEESISLTIPNNDLNSSKEKGKQNPSFKPESNPLFEK
HHHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCCCCHHHHH
LRSLRRQLADEENKPPFMIFSDATLHEMAQSKPKNSKQLLNVSGVGQHKLARYGHYFLEA
HHHHHHHHCCCCCCCCEEEECCCHHHHHHHCCCCCCHHEEECCCCCHHHHHHHHHHHHHH
LNEFSEVE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]