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The map label for this gene is trpG [H]

Identifier: 54293810

GI number: 54293810

Start: 983870

End: 984448

Strand: Reverse

Name: trpG [H]

Synonym: lpl0866

Alternate gene names: 54293810

Gene position: 984448-983870 (Counterclockwise)

Preceding gene: 54293811

Following gene: 54293809

Centisome position: 29.42

GC content: 37.48

Gene sequence:

>579_bases
ATGTTACTAATTATTGATAACTACGATTCATTTACATACAACCTGGTACAATACTTCGAGAGCTTAAATCAAAAAGTTGA
AGTTTTTAAAAATGATGAAATTCAAATCGATACTATCAGGCAATCAGCTCCGCAATACCTGGTCATTTCACCGGGACCTA
ACTCTCCTGATGAATCAGGAATCTCTATAGAAGTCATTAAAGAGTTTCACAAGCATATTCCGATATTGGGTATTTGCCTT
GGCCATCAGTGCATAGCTCAGGCATTTGGAGGTAAAATCATCCCGGCACCAGAAATCATGCATGGTAAAACCTCAGAAAT
CACCCATCATTACCAGGGTTTATTTACAGGAATACCAAATCACTTTCAAGCGACGAGATATCATTCTTTAGCCGTGGATA
TCATGAGCTTGCCCAATTGCTTTTCGATAGATGCGTGGGCAGAAGATACAATAATGGCAATATCACATCGTCAATTTCCT
CTTTTTGGTCTACAATTTCATCCTGAAGCCATATTAAGTCAATTTGGCTTGCAAATACTCGAGAATTTTTTACGCTATGA
AACCCAAATTTCTATTTGA

Upstream 100 bases:

>100_bases
CCCAAAAGCGATACTTGCCAATCAACAAGTAAGGCAAGTTTATTTGGGTGAAGAATTTGCTTTGTAGCCTCATTTAAAAG
AATACATTTTAATTATACTT

Downstream 100 bases:

>100_bases
ACAACTTCTATCCCGACAGGATTTAAGCTCAGACCAGATGCAAGAGGTCATCCATGCTTGCATGACAGGTGAATTTAGTG
ATGTGCAAATTGCAACCTTT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLLIIDNYDSFTYNLVQYFESLNQKVEVFKNDEIQIDTIRQSAPQYLVISPGPNSPDESGISIEVIKEFHKHIPILGICL
GHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPNHFQATRYHSLAVDIMSLPNCFSIDAWAEDTIMAISHRQFP
LFGLQFHPEAILSQFGLQILENFLRYETQISI

Sequences:

>Translated_192_residues
MLLIIDNYDSFTYNLVQYFESLNQKVEVFKNDEIQIDTIRQSAPQYLVISPGPNSPDESGISIEVIKEFHKHIPILGICL
GHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPNHFQATRYHSLAVDIMSLPNCFSIDAWAEDTIMAISHRQFP
LFGLQFHPEAILSQFGLQILENFLRYETQISI
>Mature_192_residues
MLLIIDNYDSFTYNLVQYFESLNQKVEVFKNDEIQIDTIRQSAPQYLVISPGPNSPDESGISIEVIKEFHKHIPILGICL
GHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPNHFQATRYHSLAVDIMSLPNCFSIDAWAEDTIMAISHRQFP
LFGLQFHPEAILSQFGLQILENFLRYETQISI

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=56.2162162162162, Blast_Score=220, Evalue=5e-59,
Organism=Escherichia coli, GI1787517, Length=191, Percent_Identity=38.2198952879581, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1788854, Length=193, Percent_Identity=25.9067357512953, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=44.3243243243243, Blast_Score=169, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21818; Mature: 21818

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIIDNYDSFTYNLVQYFESLNQKVEVFKNDEIQIDTIRQSAPQYLVISPGPNSPDESG
CEEEEECCCCHHHHHHHHHHHHHHHEEHHCCCCEEEEEECCCCCCEEEECCCCCCCCCCC
ISIEVIKEFHKHIPILGICLGHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPN
CCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCC
HFQATRYHSLAVDIMSLPNCFSIDAWAEDTIMAISHRQFPLFGLQFHPEAILSQFGLQIL
CHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCCCCEECEEECHHHHHHHHHHHHH
ENFLRYETQISI
HHHHHHHHHCCC
>Mature Secondary Structure
MLLIIDNYDSFTYNLVQYFESLNQKVEVFKNDEIQIDTIRQSAPQYLVISPGPNSPDESG
CEEEEECCCCHHHHHHHHHHHHHHHEEHHCCCCEEEEEECCCCCCEEEECCCCCCCCCCC
ISIEVIKEFHKHIPILGICLGHQCIAQAFGGKIIPAPEIMHGKTSEITHHYQGLFTGIPN
CCHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCC
HFQATRYHSLAVDIMSLPNCFSIDAWAEDTIMAISHRQFPLFGLQFHPEAILSQFGLQIL
CHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCCCCEECEEECHHHHHHHHHHHHH
ENFLRYETQISI
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6350604; 2403545; 9278503; 2546924; 8096767 [H]