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The map label for this gene is trpD [H]

Identifier: 54293809

GI number: 54293809

Start: 982858

End: 983892

Strand: Reverse

Name: trpD [H]

Synonym: lpl0865

Alternate gene names: 54293809

Gene position: 983892-982858 (Counterclockwise)

Preceding gene: 54293810

Following gene: 54293808

Centisome position: 29.41

GC content: 40.68

Gene sequence:

>1035_bases
ATGAAACCCAAATTTCTATTTGAACAACTTCTATCCCGACAGGATTTAAGCTCAGACCAGATGCAAGAGGTCATCCATGC
TTGCATGACAGGTGAATTTAGTGATGTGCAAATTGCAACCTTTCTGGCATTAATGCGCATGAAGGGTGAAACAGTCAATG
AACTTACTGCAGCGGCTAAAGTCATGAGACAATTAGCCCATAAAATAGATTTGGGAAATCCCCTGATTGATATAGTTGGC
ACTGGCGGTGATGGAAGAAATACTTTTAACGTATCGACAGCCTGTAGTTTTGTTGTAGCTGCAGCAGGAATAAAAGTTGC
AAAGCATGGTAACCGTTCTGTTTCGAGTCGTAGCGGTAGCGCTGATCTATTAGAACAAGCCGGATTTATACTCAATCTTT
CTGACTCACAGGTACAAAACTGCATCAACCAGTGCCAATTGGCTTTCTTGTTTGCGCCACATTATCATCCCGCCATGCAA
CACGCGAGAGCTGCAAGGCAACAATTAGGAATAAGAACTTTATTTAATTTACTTGGTCCACTGATTAACCCGGCTCAGGT
AAAACGACAAGTAGTTGGTGTATTTTCAACGAATTGGCTCAAAACAATAGCCACTGTTCTGGCTAACTTAGGTAGTGAAA
GATCATTAGTAATAAGCTCTCAAGATGGACTGGATGAGATTAGTATTGCAGCGAAAAGTGAAGTAGTTGAATACCGAGAT
GGAAATTTTAAGCAATGGTTCATTTCTCCTGAAGATTATGGTCTAAAGCATTCTTCTTTAGATGCAATCATAGTCGACTC
ACCAGAGCAAAGTCTGCATTTGATTCAATCCGTACTTTCAGGTGATTCTGGTCCAGCTCGAGATATAGTCCTTCTCAATT
CTGCCGCGGCCATTTATTGTGCCAAAGATGGCATATCGTTTGATGCGGCCATAGAGGAGGCAAGAATTGCCATTGATAAT
GGCAAGGCAAATCTTTGTTTTAACAAACTCCGATTATTGACCCAAACTTTAAATAAAGAATCAAATCATGAATAG

Upstream 100 bases:

>100_bases
GCAATATCACATCGTCAATTTCCTCTTTTTGGTCTACAATTTCATCCTGAAGCCATATTAAGTCAATTTGGCTTGCAAAT
ACTCGAGAATTTTTTACGCT

Downstream 100 bases:

>100_bases
TATCCTGGAACGAATAGCCAAACATAAACTAGAAGAAGTTGCAGTTGCGAAAAAAAATAAGCCTTTACATGTTCTGTCAA
AACAACAGCCGGGGGAAATA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKPKFLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAKVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDN
GKANLCFNKLRLLTQTLNKESNHE

Sequences:

>Translated_344_residues
MKPKFLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAKVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDN
GKANLCFNKLRLLTQTLNKESNHE
>Mature_344_residues
MKPKFLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAKVMRQLAHKIDLGNPLIDIVG
TGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGSADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQ
HARAARQQLGIRTLFNLLGPLINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYCAKDGISFDAAIEEARIAIDN
GKANLCFNKLRLLTQTLNKESNHE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=277, Percent_Identity=41.1552346570397, Blast_Score=197, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6320561, Length=346, Percent_Identity=31.2138728323699, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37426; Mature: 37426

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKFLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGS
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHCHHHCCCCCCCCCCCCCC
ADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYC
CCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEE
AKDGISFDAAIEEARIAIDNGKANLCFNKLRLLTQTLNKESNHE
ECCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPKFLFEQLLSRQDLSSDQMQEVIHACMTGEFSDVQIATFLALMRMKGETVNELTAAAK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VMRQLAHKIDLGNPLIDIVGTGGDGRNTFNVSTACSFVVAAAGIKVAKHGNRSVSSRSGS
HHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHHCHHHCCCCCCCCCCCCCC
ADLLEQAGFILNLSDSQVQNCINQCQLAFLFAPHYHPAMQHARAARQQLGIRTLFNLLGP
HHHHHHCCCEEECCHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINPAQVKRQVVGVFSTNWLKTIATVLANLGSERSLVISSQDGLDEISIAAKSEVVEYRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
GNFKQWFISPEDYGLKHSSLDAIIVDSPEQSLHLIQSVLSGDSGPARDIVLLNSAAAIYC
CCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEE
AKDGISFDAAIEEARIAIDNGKANLCFNKLRLLTQTLNKESNHE
ECCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA