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The map label for this gene is murG [H]

Identifier: 54293785

GI number: 54293785

Start: 957016

End: 958107

Strand: Direct

Name: murG [H]

Synonym: lpl0841

Alternate gene names: 54293785

Gene position: 957016-958107 (Clockwise)

Preceding gene: 54293784

Following gene: 54293786

Centisome position: 28.6

GC content: 39.74

Gene sequence:

>1092_bases
ATGAGCCCAAGTATTGTTTTTACCGGGGGAGGTACTGCCGGACATGTAACGCCTAATATCGCTTTGATTAAGGAATTTCG
AAAAGAAGGCTGGAATGTAGAATATATCGGCTCTGTTTCCGGAATTGAAAAGGAGATGATTGAGCCGCTGGACATTCCTT
TTCATGGAGTCAGTAGTGGTAAATTGCGCAGGTATTTTAGTTTGAAGAACTTGCTTGATCCTTTCAAAATTGTTCTGGGA
ATTATTCAATCTTCTTTGCTATTTTATAAAATCAAACCCGATGTGGTTTTTTCAAAAGGTGGCTTTGTAGCCTTTCCTGT
GGTTGTAGGCGCCTGGTTAAATCGAATTCCTGTTGTCGCTCATGAGTCTGATATGAGTCCGGGACTTGCGAATCGCCTAT
CCTTTCCTTTCGTCAATAAAATATGCCTTACTTTTGATGCTGGCAAAAAATACTTTAAGCGTCAGGATAAAATAGAAGTG
ACGGGTACTCCAATTCGTCAACAGCTATTAACTGGAAATCGAATGAAAGGATTGGAGTTATGCGGATTTAATTCCTCCAA
ACCTTGCCTGCTTGTAGTGGGAGGAAGCTTAGGGGCTGGTTCAATTAACAGTTGTATTCGAAGCGCATTGAAACAATTGA
CATCAGAATTTCAAGTTATTCATCTTTGTGGCAAAGGAAAACTTGATTCTTCGTTGGTTGGCGTGGAGGGATATTGCCAA
TTTGAATACGCCAATGAAGAGTTGGCTGATCTGTTCGCTGCTTCTTCTGTGGTGATTTCTCGAGCAGGAGCTAATTCTTT
GTATGAAATATTAGCATTAGGAAAACCACATATCTTAATTCCAATCTCTTCACAAGTAAGCAGAGGAGATCAAATTCAGA
ATGCAAGGTACTTCCAGGGATTGGGAATAAGCGTTGTGATTCAGGACGAGTTATTGAAAGCTGATGTTCTATTACAGGCA
CTACAGGACGTAATGCGAAAAAAAGATGAAATAGATAATAAAATCAAAGCATTAAAAATTGAGTCTGCCACTGATAAGAT
TGTGGCAATTATCAAGGAGCAAGCACATGTTCAAACCCCAAGGATTGTATGA

Upstream 100 bases:

>100_bases
TCGCAGACATTGCTCAAACCGGAGTGGATTTTATTTCAGTTGGATCCATCACCAAATCAATTCAAGCAATTGATTTGAGC
TTATTGATTAGGGAAACATT

Downstream 100 bases:

>100_bases
TTACATATGCCAACAGTGGCAAGAAGAGATATTGCCAAGTTTATGTGATTACATAAAAATCCCTAATAAATCTCCTCACT
TTGATGCAAAATGGGAAGAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLG
IIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEV
TGTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQA
LQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV

Sequences:

>Translated_363_residues
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLG
IIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEV
TGTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQA
LQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV
>Mature_362_residues
SPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLGI
IQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVT
GTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQF
EYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQAL
QDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=27.6536312849162, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39667; Mature: 39536

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSG
CCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
KLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCEEHHHHHHHHHHCCCEEE
HESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTPIRQQLLTGNRMKGLEL
ECCCCCCCHHHHCCCCCHHHEEEEEHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCCEEE
CGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
ECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCEEE
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQG
EEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECHHCCCCCHHCCCHHHCC
LGISVVIQDELLKADVLLQALQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCC
RIV
CCC
>Mature Secondary Structure 
SPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSG
CCCEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
KLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVA
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCEEEECCCCEEHHHHHHHHHHCCCEEE
HESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTPIRQQLLTGNRMKGLEL
ECCCCCCCHHHHCCCCCHHHEEEEEHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCCEEE
CGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQ
ECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCEEE
FEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQG
EEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECHHCCCCCHHCCCHHHCC
LGISVVIQDELLKADVLLQALQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTP
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCC
RIV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA