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The map label for this gene is plsC [H]

Identifier: 54293542

GI number: 54293542

Start: 643563

End: 644294

Strand: Reverse

Name: plsC [H]

Synonym: lpl0594

Alternate gene names: 54293542

Gene position: 644294-643563 (Counterclockwise)

Preceding gene: 54293543

Following gene: 54293541

Centisome position: 19.26

GC content: 38.11

Gene sequence:

>732_bases
ATGAAAATAAGTCGATTAAAAACTTTTTGGATAATTACCCGCCTATTTTATTACACAGGTGTTGCTTGCACTCGCTCTAT
ATTTAAGTATCTTTTTAGCACTCCTACGAGGCCATGGGTTGATAAAGTCATCCACCATTGGGTTGATCAACTCTTAAATG
CTGTGAAAGTAGAATATAAAGTAATCAATCCACATAATGTCCAGCCTCAGCCTGGCAAGGCAACGATCCTTATGTGCAAT
CATTCCAGTGCTTATGATATTCCTTTAGGCTTCAAAGCATTCCCTAATAACTCTATTCGCATGCTTGCCAAACGAGAACT
CTCCAAAATTCCACTTTTAGGGAAGGGAATGGCTGCAGCAGAATTCCCTTTTATTGACAGAAAAAACAGATTTCAAGCCG
TAAAAGATTTGGAATTTGCCCAGCAACTGATGGAAAGTGGAATTATTCTATGGATTGCACCAGAAGGAACTCGCTCAAAA
GATGGCAAACTAGCCCCATTTAAAAAAGGTGGTTTTATCAGTGCTATTCAAGCCAAGGCTACTATAATTCCCATAGGAAT
TCGCGGAGCTTTTGATATTCTCCCTGCCCGCACCTTTAATATACATTTGAATCAAAAAGCAGAAATTCATATTGGCGAGC
CTATTGATGCAGCTCAATATACAATTGAAAATAAAGAGGAATTAATCGAAAAAACCCATCAATCAATAAAAAAGCTGGTT
GAGGAGAATTGA

Upstream 100 bases:

>100_bases
TATCTATCTTTGGTTTAAAATACACGGCTTGATTTGAATCGTTCCAGTATTCCTCAACTTGTTGTATGATGGCCCTCTCA
TAATCCCATGCGCCCTAACG

Downstream 100 bases:

>100_bases
AAAAACTCACATCCCGGTTTGCTGAAAAAAGATGACTAAAAGTACCTACAATAACTAGTAAAAAAAGACCACGTTATACA
AAAAATAAAATTGATTTCTA

Product: hypothetical protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYKVINPHNVQPQPGKATILMCN
HSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAAEFPFIDRKNRFQAVKDLEFAQQLMESGIILWIAPEGTRSK
DGKLAPFKKGGFISAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYTIENKEELIEKTHQSIKKLV
EEN

Sequences:

>Translated_243_residues
MKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYKVINPHNVQPQPGKATILMCN
HSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAAEFPFIDRKNRFQAVKDLEFAQQLMESGIILWIAPEGTRSK
DGKLAPFKKGGFISAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYTIENKEELIEKTHQSIKKLV
EEN
>Mature_243_residues
MKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYKVINPHNVQPQPGKATILMCN
HSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAAEFPFIDRKNRFQAVKDLEFAQQLMESGIILWIAPEGTRSK
DGKLAPFKKGGFISAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYTIENKEELIEKTHQSIKKLV
EEN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=173, Percent_Identity=26.5895953757225, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI15100175, Length=173, Percent_Identity=26.5895953757225, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI6041665, Length=182, Percent_Identity=24.7252747252747, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789395, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=156, Percent_Identity=32.0512820512821, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=207, Percent_Identity=28.0193236714976, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364648, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582856, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582854, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27631; Mature: 27631

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEE
VINPHNVQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAA
EECCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCCCHH
EFPFIDRKNRFQAVKDLEFAQQLMESGIILWIAPEGTRSKDGKLAPFKKGGFISAIQAKA
CCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCE
TIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYTIENKEELIEKTHQSIKKLV
EEEEEECCCHHHHCCCEEEEEEECCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHH
EEN
HCC
>Mature Secondary Structure
MKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEE
VINPHNVQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAA
EECCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCCCHH
EFPFIDRKNRFQAVKDLEFAQQLMESGIILWIAPEGTRSKDGKLAPFKKGGFISAIQAKA
CCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCE
TIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYTIENKEELIEKTHQSIKKLV
EEEEEECCCHHHHCCCEEEEEEECCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHH
EEN
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]