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The map label for this gene is fpr [H]

Identifier: 54293463

GI number: 54293463

Start: 561079

End: 561813

Strand: Reverse

Name: fpr [H]

Synonym: lpl0512

Alternate gene names: 54293463

Gene position: 561813-561079 (Counterclockwise)

Preceding gene: 54293465

Following gene: 54293462

Centisome position: 16.79

GC content: 36.33

Gene sequence:

>735_bases
ATGCAAATAAATACTTTCCCCATCACTCTAGAAGAGTCTTTCATGATTTCTCCCAAGGTAAAACACTTTATATTCAATTG
TGAATTATCACCCCCTTTTGAATATTTACCAGGACATTTTATCACTATTCATTTTGAACATGATGGAAAAAACTTAAAGC
GTAGTTACAGTATTGCCAATGAACCCAAAAAGGATAATCGCATTGAATTTGCTGCAGGGTATTTCGAAGGAGGACCAGGC
ACAGAACTACTCTACAATTTAAAGCCAGGTGATGTGATCCACATCAATGGACCTTTCGGTCGTTTGATTTTTAAAGATGA
AATTCCAGGAAGATACATATTGGTAGCAACTAGTACTGGTACCACACCTTATAGAGCCATGCTTAATGAGCTTGGTCAAA
GAATAGAAAAGCATCCTGATTTGCATGTAGTCATCCTTCAAGGAGTGCAACGCAGTGAAGAGATTCTGTATCCAGATGAT
TTTCAAGCCTTTGCAAAAAAATATCCTCAAGCAAGTTTTCGTCCCTATTTAAGCCGTGTGCAAAAACAAGACTTGAAAGA
CAATGAATACAGTGGTTATGTACAACATGCATTTCCAGAACTTAATTTAAATCCAACTCGCGATATGGTTTATTTATGTG
GAAATCCAGGTATGATCGACGAGGCATTTAATTATTTAAAAGAACATGGTTTTCCCATGCAACATATTGTACGTGAAAAA
TATATTTCACGCTGA

Upstream 100 bases:

>100_bases
AAATCTATCGTGTTCATATGTTAATTATATGCGCTTAGCTCTTGCAATGCATAATTTTTCCCCTATATTAATCATTTTAG
AATAAAAGTTGATATTCCTT

Downstream 100 bases:

>100_bases
AATACCGCATTAAAAACCATTGTTAATCAGTGTCATCCTTTCGGTAAATAACCTGGATTTGACAAAAGATGACTAGTCGT
TATTTAAACTTAATAGGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQINTFPITLEESFMISPKVKHFIFNCELSPPFEYLPGHFITIHFEHDGKNLKRSYSIANEPKKDNRIEFAAGYFEGGPG
TELLYNLKPGDVIHINGPFGRLIFKDEIPGRYILVATSTGTTPYRAMLNELGQRIEKHPDLHVVILQGVQRSEEILYPDD
FQAFAKKYPQASFRPYLSRVQKQDLKDNEYSGYVQHAFPELNLNPTRDMVYLCGNPGMIDEAFNYLKEHGFPMQHIVREK
YISR

Sequences:

>Translated_244_residues
MQINTFPITLEESFMISPKVKHFIFNCELSPPFEYLPGHFITIHFEHDGKNLKRSYSIANEPKKDNRIEFAAGYFEGGPG
TELLYNLKPGDVIHINGPFGRLIFKDEIPGRYILVATSTGTTPYRAMLNELGQRIEKHPDLHVVILQGVQRSEEILYPDD
FQAFAKKYPQASFRPYLSRVQKQDLKDNEYSGYVQHAFPELNLNPTRDMVYLCGNPGMIDEAFNYLKEHGFPMQHIVREK
YISR
>Mature_244_residues
MQINTFPITLEESFMISPKVKHFIFNCELSPPFEYLPGHFITIHFEHDGKNLKRSYSIANEPKKDNRIEFAAGYFEGGPG
TELLYNLKPGDVIHINGPFGRLIFKDEIPGRYILVATSTGTTPYRAMLNELGQRIEKHPDLHVVILQGVQRSEEILYPDD
FQAFAKKYPQASFRPYLSRVQKQDLKDNEYSGYVQHAFPELNLNPTRDMVYLCGNPGMIDEAFNYLKEHGFPMQHIVREK
YISR

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=216, Percent_Identity=25, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787658, Length=224, Percent_Identity=24.5535714285714, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 28249; Mature: 28249

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQINTFPITLEESFMISPKVKHFIFNCELSPPFEYLPGHFITIHFEHDGKNLKRSYSIAN
CCCEEEEEEECCCEEECCCEEEEEEEECCCCCHHHCCCCEEEEEEECCCCCHHHHHCCCC
EPKKDNRIEFAAGYFEGGPGTELLYNLKPGDVIHINGPFGRLIFKDEIPGRYILVATSTG
CCCCCCEEEEEEEEECCCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCEEEEEECCC
TTPYRAMLNELGQRIEKHPDLHVVILQGVQRSEEILYPDDFQAFAKKYPQASFRPYLSRV
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHH
QKQDLKDNEYSGYVQHAFPELNLNPTRDMVYLCGNPGMIDEAFNYLKEHGFPMQHIVREK
HHHCCCCCCCCCCHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHH
YISR
HHCC
>Mature Secondary Structure
MQINTFPITLEESFMISPKVKHFIFNCELSPPFEYLPGHFITIHFEHDGKNLKRSYSIAN
CCCEEEEEEECCCEEECCCEEEEEEEECCCCCHHHCCCCEEEEEEECCCCCHHHHHCCCC
EPKKDNRIEFAAGYFEGGPGTELLYNLKPGDVIHINGPFGRLIFKDEIPGRYILVATSTG
CCCCCCEEEEEEEEECCCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCEEEEEECCC
TTPYRAMLNELGQRIEKHPDLHVVILQGVQRSEEILYPDDFQAFAKKYPQASFRPYLSRV
CCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHH
QKQDLKDNEYSGYVQHAFPELNLNPTRDMVYLCGNPGMIDEAFNYLKEHGFPMQHIVREK
HHHCCCCCCCCCCHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHH
YISR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]