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The map label for this gene is prmA [H]

Identifier: 54293454

GI number: 54293454

Start: 550321

End: 551190

Strand: Reverse

Name: prmA [H]

Synonym: lpl0503

Alternate gene names: 54293454

Gene position: 551190-550321 (Counterclockwise)

Preceding gene: 54293455

Following gene: 54293453

Centisome position: 16.47

GC content: 43.45

Gene sequence:

>870_bases
GTGTGGTTTCAACTAAAAATAGAACATTGTCCTAATGACAAGATTGAAGAAATAACCGAGGAACTCGAAGAATGCGGTGC
CTTGTCCATCACACTCACGGACAAAAATGACAACCCCGTTCTTGAACCAGAGCCAGGGACAACGCCTTTATGGCCTGAAG
TAATCATTCATGCCCTATTTGCCCAAGCAGAAGAGGCGCAATACGCAAGAGAACAATTAGTTGCTAAAAGACCATCTCTG
CATTGCAGTTTGGAACTGCTCGCTGATAAAAATTGGGAAAGAGCCTGGATGGATGATTTTCGACCTCAACGTTTTGGTAA
CCGCTTATGGGTCTGTCCTACTTGGCTCCCTCCCCCGGAACCTGATGCGGTTAATTTAATATTAGATCCTGGGTTAGCAT
TTGGTACAGGCACACATGCGACAACCTCCCTATGCCTAACTTGGCTGGAGCAGGCTGATTTAAAAAATAAATCAATAATA
GATTATGGTTGTGGTTCAGGAATACTCTCACTCGCGGCTATCAAGTTAGGAGCTAAACATGTCTATGCTGTTGACATAGA
TAATCAAGCCTTACAAGCCACACAAAGTAATGCACATGCCAACCATATCACTGAGAGCCAACTCTCTATCAGCTCCCCGG
AAGCATTGCAAAATCCTGTACATTTAGTTATCGCAAATATTTTGTTGGCCCCATTAATCAGTTTAAAGGAACGTTTTCAT
CAACTGCTCCCGTCAGGTGCGCATTTGGTAACATCAGGAATTCTGGAAGAACAGGCCCCTTTGCTGATTGACGCTTATGA
TTCCGCATTCACTCATATTGCAACTGAATATTGTGAGGGATGGTCGTTGCTGGTTTTTACAAGCAAATAA

Upstream 100 bases:

>100_bases
ACAAATATTGAATTACACCAACGTATTCTTCATGACAAATCTTTTATGGAAGGTGGCACAAACATTCACTATCTAGAAAA
AATGCTCAAGGATTCATAGC

Downstream 100 bases:

>100_bases
TAACTATATCACTAAGGTATATGTAAATGGCGAAAAAACAAATTTACTCTTCTTTCAAGCCACGACGAGCACTACTGAGT
GTTTCCGATAAAAGAGGAAT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MWFQLKIEHCPNDKIEEITEELEECGALSITLTDKNDNPVLEPEPGTTPLWPEVIIHALFAQAEEAQYAREQLVAKRPSL
HCSLELLADKNWERAWMDDFRPQRFGNRLWVCPTWLPPPEPDAVNLILDPGLAFGTGTHATTSLCLTWLEQADLKNKSII
DYGCGSGILSLAAIKLGAKHVYAVDIDNQALQATQSNAHANHITESQLSISSPEALQNPVHLVIANILLAPLISLKERFH
QLLPSGAHLVTSGILEEQAPLLIDAYDSAFTHIATEYCEGWSLLVFTSK

Sequences:

>Translated_289_residues
MWFQLKIEHCPNDKIEEITEELEECGALSITLTDKNDNPVLEPEPGTTPLWPEVIIHALFAQAEEAQYAREQLVAKRPSL
HCSLELLADKNWERAWMDDFRPQRFGNRLWVCPTWLPPPEPDAVNLILDPGLAFGTGTHATTSLCLTWLEQADLKNKSII
DYGCGSGILSLAAIKLGAKHVYAVDIDNQALQATQSNAHANHITESQLSISSPEALQNPVHLVIANILLAPLISLKERFH
QLLPSGAHLVTSGILEEQAPLLIDAYDSAFTHIATEYCEGWSLLVFTSK
>Mature_289_residues
MWFQLKIEHCPNDKIEEITEELEECGALSITLTDKNDNPVLEPEPGTTPLWPEVIIHALFAQAEEAQYAREQLVAKRPSL
HCSLELLADKNWERAWMDDFRPQRFGNRLWVCPTWLPPPEPDAVNLILDPGLAFGTGTHATTSLCLTWLEQADLKNKSII
DYGCGSGILSLAAIKLGAKHVYAVDIDNQALQATQSNAHANHITESQLSISSPEALQNPVHLVIANILLAPLISLKERFH
QLLPSGAHLVTSGILEEQAPLLIDAYDSAFTHIATEYCEGWSLLVFTSK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=276, Percent_Identity=46.3768115942029, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32057; Mature: 32057

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFQLKIEHCPNDKIEEITEELEECGALSITLTDKNDNPVLEPEPGTTPLWPEVIIHALF
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
AQAEEAQYAREQLVAKRPSLHCSLELLADKNWERAWMDDFRPQRFGNRLWVCPTWLPPPE
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCHHHHCCEEEEECCCCCCCC
PDAVNLILDPGLAFGTGTHATTSLCLTWLEQADLKNKSIIDYGCGSGILSLAAIKLGAKH
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCE
VYAVDIDNQALQATQSNAHANHITESQLSISSPEALQNPVHLVIANILLAPLISLKERFH
EEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHH
QLLPSGAHLVTSGILEEQAPLLIDAYDSAFTHIATEYCEGWSLLVFTSK
HHCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MWFQLKIEHCPNDKIEEITEELEECGALSITLTDKNDNPVLEPEPGTTPLWPEVIIHALF
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
AQAEEAQYAREQLVAKRPSLHCSLELLADKNWERAWMDDFRPQRFGNRLWVCPTWLPPPE
HHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCHHHHCCEEEEECCCCCCCC
PDAVNLILDPGLAFGTGTHATTSLCLTWLEQADLKNKSIIDYGCGSGILSLAAIKLGAKH
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCE
VYAVDIDNQALQATQSNAHANHITESQLSISSPEALQNPVHLVIANILLAPLISLKERFH
EEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHH
QLLPSGAHLVTSGILEEQAPLLIDAYDSAFTHIATEYCEGWSLLVFTSK
HHCCCCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA