| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is pacS [H]
Identifier: 54293236
GI number: 54293236
Start: 318534
End: 321092
Strand: Reverse
Name: pacS [H]
Synonym: lpl0284
Alternate gene names: 54293236
Gene position: 321092-318534 (Counterclockwise)
Preceding gene: 54293238
Following gene: 54293235
Centisome position: 9.6
GC content: 40.56
Gene sequence:
>2559_bases ATGCTGTATAGTAATTATCGATTCTACCTTGCAAAAGATGCCCAACTTCTCAACCCGGAAGAATCCAGAGAAGCAATTGA GCTGATTTTAGCTAAAACTAAAGAGTTGGAGTTAATAAGAGTAGCTGTCGATTTGACTAGTTCCAATAAAAGCATCAGCT TATTGAGCGCATCCAGAGAGAATCATGTCATAAAAACCAAAGTGACCCAGATTTTAAAGGAGCAGGGTCTTTCTGTAATA GACATGATGGAAGTGGAAGTACTCCAGGATATTGAAAAAATAGAGCATCACCATCCTACTCATAAGTCTAAGAACACACA TCTTCATCCCATTAAAAAGCACCAAAAAAAAGCAAAACATGACCATTCTCATGGGCATGGGCACCACCATGGACATCATC ATGAAAATCATTGGATCAAAGCAGCATTAGGTTTGATTTGGGGAATTGGATTACTTGTTCTTTCTATTGGGACTTTTAAT ATTCCCCTGGTTGCTTACTATGTCATTACAGGACTTACCTCTTTGTTGACTTTGTATTTGGGGCATACGGTTTATCAATC AGCCTGGCAAGCATTGAAAGAAAAAAAATGGGACACCACTACTTTATACTCAATTAGCACTCTAACTATTCTTGCTGTTT CTATTACGAGCGTTTTTGTCCCTGGCCTACCCATGATGTTTGAGGCAGCCCCTCTGGTTTTAGGCTTTTGGCATTTAGGT GAAGGAATTGAACATACTCTGGTCGGTAAAATCAATAAAAAATTGGATGTCCGGGATTGTGTACCACCATTAGTCCTGTT AAAAGGTAATCCGGATAAAGAGATTTCAGTCAAGACATTAATTCCTAACGACATGATTATCGTTAAAAAAGGACAGGTCA TTCCTGTTGATGGTGTCTTAACGCAAAAAGCGCTCCTTTATACCACAAGAATTGATGGCTCGCCCAAACTCAAAGAATTT CACCCTGGGGATGTTGTAAAAGCCGGCATGCAATTGGCAGATCATATTCCTTCTCTGGCAATGCAGGTTACCAAAACTTA TCAAAATTCTTATTTGTCATTGATTGCCGAAAACATTAATAAAGCGAATGATGAGAAAGCGCCTATCGAAATGTTTGCAG ACAAAGTATTGAAATATTTTATTCCTGGTTTGATTGCGGTAGCGCTCCTATCGGGGATTGTCATCGGTTCGTTGTTTAAC CCGGCACTGGCTATTCAATGCGTCGTGTCTGTTCTGGTAAGTGCCTGCCCGTGCGCTTTGAGTTTAATTACCCCAATGGC AGTTAAAATCGGTATGAAAAAAGCCTCTGAAAACGGCATCCACTTTAACAACGGTAAAGCCTTGCAAGCAGCAGCCGACA TTGACACCGTTGTTTTTGATTTAAATGGCACTCTGACTCAGGGCAAATTGTTGGTGAAATCATTGCATATTACCGATAAA AAGTATTTGCGCCCTATTGCATTACTGGAAAGCCAGTCGGATCATCCGGTAGCGAAAATTATTAAATCTTACATCGAACA GCAAGACACGGCCTCAAACGAACCATTAGAAATAACGTCAATTGATAAGAGTCATCATTCCGGCATGAAAGGTATTATTA ATGGCAAGGTCTTTATGATAGGGAATAAAGACATGCTTGTCGCCAATGGAATTACCTCTATCGACAAACCCTATGATAAT CCTGAAAAAGGTTCAGTTTATATTGTGCGTGGGACAACGGTGATAGGTCAAATTGCCTTAATTGATCCGTTGCGAGAGGA TGCCATTGCCACAGTGAAACAATTGAAACGTCTTGGTAAATCCGTACATATTTGCACCGGGGCAGATCAAGCTACAGCAG AAAAATATGCGGCATTATTAGGCATTCCCAAGGATAATATCTGTACGAACACTGTGGGGGCTGTCACGCAAAAGGGGGAA GTATCCAAAACCAGTTATATTCAACAATTAAAGCAAAAAGGCTTTAAAGTAGCTATGGTTGGTGATGCCGCTAATGATGC TACCGCAATTGCCTATTCCGATATAGGCATTGCTGTTAAATCAAGTATCGGCGACTCCATAACCGAACAACATGCCGGCA TAGTCGTACAACAAGGGTTATTATTTCCTATAGCAACAGCATTTGATGTAGCCCAAAAAACCAAACAAAATATTTTCCAA AACCTGTTCGTGAGCCTAAGCTATAACTCAATAATTACGCTTGTAGCAGCGGGGTTGTTTGTGGCATTAGGTTTTGCACT AAATCCTGTGCTGGGTGTCGGATTGATGGTGCTTGAATCCACTATTGTTTTGACGAACTTATACCTTTTCAAGCAACAAG ACATTGTGTCCTCAACATCATCCAATGCCAATAATGCTGTAGAGGTCGAGCCCACTGCCAATACAACATCAAAAGTCTTG CATGCTTTAGGGCATCGTTCCCAGCCCCAAGAAAATTTAGCAATTGTGACAGAGTCTAAACCGGTCAATCCCAAAGTAAT AAATTTGTTTGCGCCTAAAGAACATCCTTCTTATAGGTCTGATGTCACTCAACAAAAATTGGGGTGTGGAATCTGTTGA
Upstream 100 bases:
>100_bases CAGCTGGATCTATTGTGCAGATCAAGTTTCAAAATAGGCATTTGCAGAAAATTAACCTTTCTCTATAGCAACCAGAAACC CCTTTAAATAGAGGAAAGCC
Downstream 100 bases:
>100_bases TCAAGCGGTACTGAAATTGCCTTGATTTTCTACTTCAAGGCAGTTGTTACTCCTGATGCCTCATAAGTAACTGTTTTTTG GACTATACTCTTATCAAGAC
Product: hypothetical protein
Products: ADP; Orthophosphate. [C]
Alternate protein names: NA
Number of amino acids: Translated: 852; Mature: 852
Protein sequence:
>852_residues MLYSNYRFYLAKDAQLLNPEESREAIELILAKTKELELIRVAVDLTSSNKSISLLSASRENHVIKTKVTQILKEQGLSVI DMMEVEVLQDIEKIEHHHPTHKSKNTHLHPIKKHQKKAKHDHSHGHGHHHGHHHENHWIKAALGLIWGIGLLVLSIGTFN IPLVAYYVITGLTSLLTLYLGHTVYQSAWQALKEKKWDTTTLYSISTLTILAVSITSVFVPGLPMMFEAAPLVLGFWHLG EGIEHTLVGKINKKLDVRDCVPPLVLLKGNPDKEISVKTLIPNDMIIVKKGQVIPVDGVLTQKALLYTTRIDGSPKLKEF HPGDVVKAGMQLADHIPSLAMQVTKTYQNSYLSLIAENINKANDEKAPIEMFADKVLKYFIPGLIAVALLSGIVIGSLFN PALAIQCVVSVLVSACPCALSLITPMAVKIGMKKASENGIHFNNGKALQAAADIDTVVFDLNGTLTQGKLLVKSLHITDK KYLRPIALLESQSDHPVAKIIKSYIEQQDTASNEPLEITSIDKSHHSGMKGIINGKVFMIGNKDMLVANGITSIDKPYDN PEKGSVYIVRGTTVIGQIALIDPLREDAIATVKQLKRLGKSVHICTGADQATAEKYAALLGIPKDNICTNTVGAVTQKGE VSKTSYIQQLKQKGFKVAMVGDAANDATAIAYSDIGIAVKSSIGDSITEQHAGIVVQQGLLFPIATAFDVAQKTKQNIFQ NLFVSLSYNSIITLVAAGLFVALGFALNPVLGVGLMVLESTIVLTNLYLFKQQDIVSSTSSNANNAVEVEPTANTTSKVL HALGHRSQPQENLAIVTESKPVNPKVINLFAPKEHPSYRSDVTQQKLGCGIC
Sequences:
>Translated_852_residues MLYSNYRFYLAKDAQLLNPEESREAIELILAKTKELELIRVAVDLTSSNKSISLLSASRENHVIKTKVTQILKEQGLSVI DMMEVEVLQDIEKIEHHHPTHKSKNTHLHPIKKHQKKAKHDHSHGHGHHHGHHHENHWIKAALGLIWGIGLLVLSIGTFN IPLVAYYVITGLTSLLTLYLGHTVYQSAWQALKEKKWDTTTLYSISTLTILAVSITSVFVPGLPMMFEAAPLVLGFWHLG EGIEHTLVGKINKKLDVRDCVPPLVLLKGNPDKEISVKTLIPNDMIIVKKGQVIPVDGVLTQKALLYTTRIDGSPKLKEF HPGDVVKAGMQLADHIPSLAMQVTKTYQNSYLSLIAENINKANDEKAPIEMFADKVLKYFIPGLIAVALLSGIVIGSLFN PALAIQCVVSVLVSACPCALSLITPMAVKIGMKKASENGIHFNNGKALQAAADIDTVVFDLNGTLTQGKLLVKSLHITDK KYLRPIALLESQSDHPVAKIIKSYIEQQDTASNEPLEITSIDKSHHSGMKGIINGKVFMIGNKDMLVANGITSIDKPYDN PEKGSVYIVRGTTVIGQIALIDPLREDAIATVKQLKRLGKSVHICTGADQATAEKYAALLGIPKDNICTNTVGAVTQKGE VSKTSYIQQLKQKGFKVAMVGDAANDATAIAYSDIGIAVKSSIGDSITEQHAGIVVQQGLLFPIATAFDVAQKTKQNIFQ NLFVSLSYNSIITLVAAGLFVALGFALNPVLGVGLMVLESTIVLTNLYLFKQQDIVSSTSSNANNAVEVEPTANTTSKVL HALGHRSQPQENLAIVTESKPVNPKVINLFAPKEHPSYRSDVTQQKLGCGIC >Mature_852_residues MLYSNYRFYLAKDAQLLNPEESREAIELILAKTKELELIRVAVDLTSSNKSISLLSASRENHVIKTKVTQILKEQGLSVI DMMEVEVLQDIEKIEHHHPTHKSKNTHLHPIKKHQKKAKHDHSHGHGHHHGHHHENHWIKAALGLIWGIGLLVLSIGTFN IPLVAYYVITGLTSLLTLYLGHTVYQSAWQALKEKKWDTTTLYSISTLTILAVSITSVFVPGLPMMFEAAPLVLGFWHLG EGIEHTLVGKINKKLDVRDCVPPLVLLKGNPDKEISVKTLIPNDMIIVKKGQVIPVDGVLTQKALLYTTRIDGSPKLKEF HPGDVVKAGMQLADHIPSLAMQVTKTYQNSYLSLIAENINKANDEKAPIEMFADKVLKYFIPGLIAVALLSGIVIGSLFN PALAIQCVVSVLVSACPCALSLITPMAVKIGMKKASENGIHFNNGKALQAAADIDTVVFDLNGTLTQGKLLVKSLHITDK KYLRPIALLESQSDHPVAKIIKSYIEQQDTASNEPLEITSIDKSHHSGMKGIINGKVFMIGNKDMLVANGITSIDKPYDN PEKGSVYIVRGTTVIGQIALIDPLREDAIATVKQLKRLGKSVHICTGADQATAEKYAALLGIPKDNICTNTVGAVTQKGE VSKTSYIQQLKQKGFKVAMVGDAANDATAIAYSDIGIAVKSSIGDSITEQHAGIVVQQGLLFPIATAFDVAQKTKQNIFQ NLFVSLSYNSIITLVAAGLFVALGFALNPVLGVGLMVLESTIVLTNLYLFKQQDIVSSTSSNANNAVEVEPTANTTSKVL HALGHRSQPQENLAIVTESKPVNPKVINLFAPKEHPSYRSDVTQQKLGCGIC
Specific function: May play a role in the osmotic adaptation [H]
COG id: COG2217
COG function: function code P; Cation transport ATPase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HMA domain [H]
Homologues:
Organism=Homo sapiens, GI115529486, Length=678, Percent_Identity=26.8436578171091, Blast_Score=195, Evalue=1e-49, Organism=Homo sapiens, GI55743071, Length=735, Percent_Identity=26.2585034013605, Blast_Score=186, Evalue=6e-47, Organism=Homo sapiens, GI55743073, Length=533, Percent_Identity=26.8292682926829, Blast_Score=144, Evalue=4e-34, Organism=Escherichia coli, GI1786691, Length=670, Percent_Identity=29.7014925373134, Blast_Score=209, Evalue=4e-55, Organism=Escherichia coli, GI1789879, Length=615, Percent_Identity=28.4552845528455, Blast_Score=148, Evalue=1e-36, Organism=Escherichia coli, GI1786914, Length=444, Percent_Identity=26.3513513513513, Blast_Score=86, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17556548, Length=686, Percent_Identity=25.2186588921283, Blast_Score=159, Evalue=7e-39, Organism=Saccharomyces cerevisiae, GI6320475, Length=636, Percent_Identity=28.6163522012579, Blast_Score=202, Evalue=2e-52, Organism=Saccharomyces cerevisiae, GI6319772, Length=647, Percent_Identity=25.8114374034003, Blast_Score=154, Evalue=4e-38, Organism=Drosophila melanogaster, GI221329854, Length=407, Percent_Identity=28.7469287469287, Blast_Score=108, Evalue=2e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008250 - InterPro: IPR006403 - InterPro: IPR006416 - InterPro: IPR001757 - InterPro: IPR018303 - InterPro: IPR005834 - InterPro: IPR023214 - InterPro: IPR017969 - InterPro: IPR006121 [H]
Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]
EC number: 3.6.3.4 [C]
Molecular weight: Translated: 92763; Mature: 92763
Theoretical pI: Translated: 8.85; Mature: 8.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLYSNYRFYLAKDAQLLNPEESREAIELILAKTKELELIRVAVDLTSSNKSISLLSASRE CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEEECCCC NHVIKTKVTQILKEQGLSVIDMMEVEVLQDIEKIEHHHPTHKSKNTHLHPIKKHQKKAKH CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC DHSHGHGHHHGHHHENHWIKAALGLIWGIGLLVLSIGTFNIPLVAYYVITGLTSLLTLYL CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH GHTVYQSAWQALKEKKWDTTTLYSISTLTILAVSITSVFVPGLPMMFEAAPLVLGFWHLG HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC EGIEHTLVGKINKKLDVRDCVPPLVLLKGNPDKEISVKTLIPNDMIIVKKGQVIPVDGVL CCCCHHHHHHHCCCCCHHHCCCCEEEEECCCCCCEEEEEECCCCEEEEECCCEEECCCHH TQKALLYTTRIDGSPKLKEFHPGDVVKAGMQLADHIPSLAMQVTKTYQNSYLSLIAENIN HCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KANDEKAPIEMFADKVLKYFIPGLIAVALLSGIVIGSLFNPALAIQCVVSVLVSACPCAL CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SLITPMAVKIGMKKASENGIHFNNGKALQAAADIDTVVFDLNGTLTQGKLLVKSLHITDK HHHHHHHHHHHHHHCCCCCCEECCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCH KYLRPIALLESQSDHPVAKIIKSYIEQQDTASNEPLEITSIDKSHHSGMKGIINGKVFMI HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCCEEECCEEEEE GNKDMLVANGITSIDKPYDNPEKGSVYIVRGTTVIGQIALIDPLREDAIATVKQLKRLGK CCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHCHHHHHHHHHHHHHHHHCC SVHICTGADQATAEKYAALLGIPKDNICTNTVGAVTQKGEVSKTSYIQQLKQKGFKVAMV EEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCEEEEE GDAANDATAIAYSDIGIAVKSSIGDSITEQHAGIVVQQGLLFPIATAFDVAQKTKQNIFQ ECCCCCCEEEEEECCCEEEHHHCCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHH NLFVSLSYNSIITLVAAGLFVALGFALNPVLGVGLMVLESTIVLTNLYLFKQQDIVSSTS HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC SNANNAVEVEPTANTTSKVLHALGHRSQPQENLAIVTESKPVNPKVINLFAPKEHPSYRS CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHH DVTQQKLGCGIC HHHHHHHCCCCC >Mature Secondary Structure MLYSNYRFYLAKDAQLLNPEESREAIELILAKTKELELIRVAVDLTSSNKSISLLSASRE CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCEEEEEECCCC NHVIKTKVTQILKEQGLSVIDMMEVEVLQDIEKIEHHHPTHKSKNTHLHPIKKHQKKAKH CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC DHSHGHGHHHGHHHENHWIKAALGLIWGIGLLVLSIGTFNIPLVAYYVITGLTSLLTLYL CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH GHTVYQSAWQALKEKKWDTTTLYSISTLTILAVSITSVFVPGLPMMFEAAPLVLGFWHLG HHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC EGIEHTLVGKINKKLDVRDCVPPLVLLKGNPDKEISVKTLIPNDMIIVKKGQVIPVDGVL CCCCHHHHHHHCCCCCHHHCCCCEEEEECCCCCCEEEEEECCCCEEEEECCCEEECCCHH TQKALLYTTRIDGSPKLKEFHPGDVVKAGMQLADHIPSLAMQVTKTYQNSYLSLIAENIN HCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KANDEKAPIEMFADKVLKYFIPGLIAVALLSGIVIGSLFNPALAIQCVVSVLVSACPCAL CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SLITPMAVKIGMKKASENGIHFNNGKALQAAADIDTVVFDLNGTLTQGKLLVKSLHITDK HHHHHHHHHHHHHHCCCCCCEECCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCH KYLRPIALLESQSDHPVAKIIKSYIEQQDTASNEPLEITSIDKSHHSGMKGIINGKVFMI HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCCEEECCEEEEE GNKDMLVANGITSIDKPYDNPEKGSVYIVRGTTVIGQIALIDPLREDAIATVKQLKRLGK CCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHCHHHHHHHHHHHHHHHHCC SVHICTGADQATAEKYAALLGIPKDNICTNTVGAVTQKGEVSKTSYIQQLKQKGFKVAMV EEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCEEEEE GDAANDATAIAYSDIGIAVKSSIGDSITEQHAGIVVQQGLLFPIATAFDVAQKTKQNIFQ ECCCCCCEEEEEECCCEEEHHHCCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHH NLFVSLSYNSIITLVAAGLFVALGFALNPVLGVGLMVLESTIVLTNLYLFKQQDIVSSTS HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC SNANNAVEVEPTANTTSKVLHALGHRSQPQENLAIVTESKPVNPKVINLFAPKEHPSYRS CCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHH DVTQQKLGCGIC HHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: Cu [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; H2O [C]
Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]
General reaction: Phosphorous acid anhydride hydrolysis [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]