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The map label for this gene is yfnA [H]

Identifier: 54292991

GI number: 54292991

Start: 32290

End: 33681

Strand: Direct

Name: yfnA [H]

Synonym: lpl0027

Alternate gene names: 54292991

Gene position: 32290-33681 (Clockwise)

Preceding gene: 54292987

Following gene: 54292994

Centisome position: 0.97

GC content: 40.52

Gene sequence:

>1392_bases
ATGGACTTGTTTCGTAAAAAAGATATAAAAGGGTCGCCAGACAGTGAATCACATTTAGCTAAATGCCTTAGTGTTTTTGA
CCTTACCTTTTTGGGAGTGGGTGCGATTATAGGTGCTGGTATTTTCGTTCTTACAGGAATAGTTGCTGCCACTATAAGCG
GACCAGCCGTGATATTCTCCTATGTTGTTGCCGGATTTGCCTGCGCCTTTGCCGCCTTATCCTATGCTGAGTTGGCTGCC
AGCATAGGGGGGTGTGGCAGTGCTTATGGATATGCTTACGCAGGTTTTGGTGAGTTAATCGCGTGGATCGTCGGATGGGA
TTTGTTATTGGAATATTCTATTGCTGTATCGGCTGTTTCCATCGGCTGGAGTGGTTATGCCAATGATTTTTTAATGGCTC
TGAAAATATTTATTCCAACTCATTTATTACATGGTCCCGCTGACGGTGGGGATCTCAATATTTTAGCCATTTTGATCATA
GCTGTTTTAACTACATTATTAATTGTTGGTGTGAAATCCAGTTCTCGATTTAATAATATCATGGTGCTTGTTAAGCTTTT
GGTTATTTTTATTTTCATAGCTATCGCATTTGGTGAAGTGAAGGTTGAAAATTGGTCTTCTTTCATGCCCTATGGTTGGG
CTGGTGTTATGAAAGGTGCTTCAATCATCTTTTTTGCCTACGTGGGGTTTGATGCTGTATCTACTGCTGCTGAAGAAGCA
ATTAATCCTCAACGGGACTTACCCATAGGGATAATCGCTTCTCTGGCTATTTGTACAGTGATCTATATTCTGGTTTCAGG
TTTATTAACCGGGATTGCTCATTACACTACCCTTAACGTTTCATCACCAATCAGTCATGTCCTGCTTGTCTTGGGTTATA
AAACAGCAGCCGGACTGGTCGGTGTAGGCGCAATTGCTGGTTTAACCACAGTTATGTTAGTCCTGTTCTATGGATTAACC
AGAGTATTTTTAGCAATGTCAAGGGATGGCTTATTGCCAAGGTTCTTATCCAAAACGAACGAACACACTAAAACACCAAT
TCGAATTATATTGCTATGTGGCATATTAATGGCATCTCTCGCTTCAGTAACTCCAATTGGTACCTTGGCCGAGCTGGTTA
ATATTGGAACCTTGTTTGCCTTTATTGTTGTTTGTGGGGGTGTTTTATATTTAAGGCGAACTCATCCTGATATGGAAAGG
CCATTCAAAACACCTTTTATGCCTTATGTTCCTATATTAGGTATAATAAGCTGCTTTTATTTAATTTTGAATTTGCCATG
GGTAACGATATTGCGTTTTATAATTTGGATGCTAGTTGGTATAGCGGTCTATTTTGCATTTAGCAGGACAAATAGTGCCT
TAAGTGTTGAGGGAGATTGTGCTGCCGAGTGA

Upstream 100 bases:

>100_bases
TGTAAGGTTTTGTTAGATGGAAGATAACCGGAGTTTATGTTTATTGATAACTTAAATTTTGGAAATAAACAATAAAAAAT
AAACCTGAGAGCATACTATC

Downstream 100 bases:

>100_bases
CGCCATAATCTAGGCAGTTGGTGAGATAGTCATAATAGCGGCAGCAACTAATGCTGCTGCTGGAATGGTAAGCAACCAAG
AGTAGAATATCCTGCGTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDLFRKKDIKGSPDSESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFSYVVAGFACAFAALSYAELAA
SIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVSIGWSGYANDFLMALKIFIPTHLLHGPADGGDLNILAILII
AVLTTLLIVGVKSSSRFNNIMVLVKLLVIFIFIAIAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLVGVGAIAGLTTVMLVLFYGLT
RVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASLASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMER
PFKTPFMPYVPILGIISCFYLILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE

Sequences:

>Translated_463_residues
MDLFRKKDIKGSPDSESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFSYVVAGFACAFAALSYAELAA
SIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVSIGWSGYANDFLMALKIFIPTHLLHGPADGGDLNILAILII
AVLTTLLIVGVKSSSRFNNIMVLVKLLVIFIFIAIAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLVGVGAIAGLTTVMLVLFYGLT
RVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASLASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMER
PFKTPFMPYVPILGIISCFYLILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE
>Mature_463_residues
MDLFRKKDIKGSPDSESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFSYVVAGFACAFAALSYAELAA
SIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVSIGWSGYANDFLMALKIFIPTHLLHGPADGGDLNILAILII
AVLTTLLIVGVKSSSRFNNIMVLVKLLVIFIFIAIAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLVGVGAIAGLTTVMLVLFYGLT
RVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASLASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMER
PFKTPFMPYVPILGIISCFYLILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=36.9515011547344, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI258645169, Length=422, Percent_Identity=35.3080568720379, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI258614005, Length=422, Percent_Identity=35.781990521327, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI258614003, Length=422, Percent_Identity=35.781990521327, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI114326544, Length=429, Percent_Identity=35.1981351981352, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI114326550, Length=429, Percent_Identity=35.1981351981352, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI181337167, Length=386, Percent_Identity=38.0829015544041, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI110347453, Length=399, Percent_Identity=37.593984962406, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI115648063, Length=444, Percent_Identity=28.3783783783784, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI115648022, Length=444, Percent_Identity=28.3783783783784, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI7657683, Length=417, Percent_Identity=27.3381294964029, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI186910308, Length=417, Percent_Identity=28.0575539568345, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI186910306, Length=417, Percent_Identity=28.0575539568345, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI186910304, Length=417, Percent_Identity=28.0575539568345, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI71979932, Length=439, Percent_Identity=27.3348519362187, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI33286428, Length=449, Percent_Identity=26.2806236080178, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI187423910, Length=472, Percent_Identity=25.635593220339, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI7657591, Length=472, Percent_Identity=25.635593220339, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI9790235, Length=315, Percent_Identity=24.1269841269841, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081869, Length=469, Percent_Identity=24.7334754797441, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082023, Length=448, Percent_Identity=25.8928571428571, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI2367353, Length=407, Percent_Identity=25.0614250614251, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789017, Length=357, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081708, Length=449, Percent_Identity=19.8218262806236, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790653, Length=419, Percent_Identity=21.2410501193317, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786694, Length=382, Percent_Identity=22.2513089005236, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786789, Length=421, Percent_Identity=21.6152019002375, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788480, Length=456, Percent_Identity=23.2456140350877, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786602, Length=416, Percent_Identity=21.875, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=403, Percent_Identity=37.7171215880893, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17531343, Length=401, Percent_Identity=36.6583541147132, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17533459, Length=405, Percent_Identity=35.0617283950617, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17540018, Length=451, Percent_Identity=27.9379157427938, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17568033, Length=478, Percent_Identity=27.6150627615063, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17537453, Length=380, Percent_Identity=22.6315789473684, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=25.4010695187166, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71993915, Length=392, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=37.9227053140097, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=37.9227053140097, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24667468, Length=402, Percent_Identity=37.0646766169154, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24668806, Length=410, Percent_Identity=36.3414634146341, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI21356285, Length=410, Percent_Identity=36.3414634146341, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24668802, Length=410, Percent_Identity=36.3414634146341, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI161077963, Length=400, Percent_Identity=34.25, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=32.518337408313, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=32.518337408313, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI116007818, Length=409, Percent_Identity=32.518337408313, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI85725152, Length=409, Percent_Identity=32.518337408313, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI45550968, Length=472, Percent_Identity=26.9067796610169, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19921172, Length=472, Percent_Identity=26.9067796610169, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357367, Length=439, Percent_Identity=26.4236902050114, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI221331183, Length=460, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17647653, Length=460, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24664379, Length=460, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24651635, Length=417, Percent_Identity=25.8992805755396, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651633, Length=417, Percent_Identity=25.8992805755396, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49390; Mature: 49390

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFRKKDIKGSPDSESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YVVAGFACAFAALSYAELAASIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGWSGYANDFLMALKIFIPTHLLHGPADGGDLNILAILIIAVLTTLLIVGVKSSSRFNNI
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MVLVKLLVIFIFIAIAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GVGAIAGLTTVMLVLFYGLTRVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMERPFKTPFMPYVPILGIISCFY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MDLFRKKDIKGSPDSESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YVVAGFACAFAALSYAELAASIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGWSGYANDFLMALKIFIPTHLLHGPADGGDLNILAILIIAVLTTLLIVGVKSSSRFNNI
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MVLVKLLVIFIFIAIAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GVGAIAGLTTVMLVLFYGLTRVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMERPFKTPFMPYVPILGIISCFY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]