Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 54297206

GI number: 54297206

Start: 1388148

End: 1388747

Strand: Direct

Name: ruvA

Synonym: lpp1251

Alternate gene names: 54297206

Gene position: 1388148-1388747 (Clockwise)

Preceding gene: 54297205

Following gene: 54297207

Centisome position: 39.62

GC content: 39.33

Gene sequence:

>600_bases
ATGATAGGCTGGCTCCATGGTCAAATTATAGATAAGCATCAGCCAGGAAAATTGGTTCTGGATGTCAATGGCGTAGGATA
TGATGTAGAAACATCTTTGAATACTTTTTTTCAGATAGAAAATGGTAACCAACCTATCGGATTACATATTCACACCATAG
TTCGAGAAGATGCTTTGTTATTGTATGGCTTCCTGGATAAAGAGGAGCGTTCTTTATTCAGATCATTAATTAAAGTGAAT
GGGGTAGGCCCCAAACTGGCTATGACTGTTTTATCCAGTATTTCTCCTAAAGAATTTATTCAGTGTATTCACCAGGAGAA
TGCTGCTTTATTAACCAAATTACCTGGCATAGGCAAGAAAACTGCAGAGCGCTTAGTAGTTGAAATGAGAGACAGTATAA
AGCAGTTTGATGGTTCGGTTTCCGATACTTTCCAAAAGCAGGCAGGTAGCACTCATAGTCAACAAGAGGCAATCAGCGCG
TTGGAGGCATTAGGCTATAAGCCACAAGAGGCTTGGAAAGTTGTGAATAAAATTGATAATGGCAATAAGAGTTGTGAGCA
ATTGATTCGTGAGGCTTTGCAAATTCTTTCTTCGCGATGA

Upstream 100 bases:

>100_bases
CTGCCGATGCTTTGGCAATAGCAATATGTCATAGCCATATGAGAAATGGTTTGTCAAAATTAATCGGTTCAAGAGGAACG
AAACGCAGGAGGATGAGACT

Downstream 100 bases:

>100_bases
GATTGTAACTGTGATCTGATAAAATTCTCGATAATAAACAGGAGCATTTATGAAAAGAATGATCGGTTTTATGGTAAGTG
TGATGCTAACCTTTGCTGTC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPIGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVN
GVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISA
LEALGYKPQEAWKVVNKIDNGNKSCEQLIREALQILSSR

Sequences:

>Translated_199_residues
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPIGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVN
GVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISA
LEALGYKPQEAWKVVNKIDNGNKSCEQLIREALQILSSR
>Mature_199_residues
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPIGLHIHTIVREDALLLYGFLDKEERSLFRSLIKVN
GVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKKTAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISA
LEALGYKPQEAWKVVNKIDNGNKSCEQLIREALQILSSR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=48.0392156862745, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_LEGPA (Q5X5R9)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123575.1
- ProteinModelPortal:   Q5X5R9
- SMR:   Q5X5R9
- STRING:   Q5X5R9
- GeneID:   3117529
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1251
- LegioList:   lpp1251
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   LPNE297246:LPP1251-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22108; Mature: 22108

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPIGLHIHTIVREDALL
CCCCCCCCEECCCCCCEEEEEECCCCEEHCCCCCEEEEECCCCCCEEEEEHHHHHHCHHH
LYGFLDKEERSLFRSLIKVNGVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKK
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCHH
TAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISALEALGYKPQEAWKVVNKIDN
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GNKSCEQLIREALQILSSR
CCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGWLHGQIIDKHQPGKLVLDVNGVGYDVETSLNTFFQIENGNQPIGLHIHTIVREDALL
CCCCCCCCEECCCCCCEEEEEECCCCEEHCCCCCEEEEECCCCCCEEEEEHHHHHHCHHH
LYGFLDKEERSLFRSLIKVNGVGPKLAMTVLSSISPKEFIQCIHQENAALLTKLPGIGKK
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHCCCCCHH
TAERLVVEMRDSIKQFDGSVSDTFQKQAGSTHSQQEAISALEALGYKPQEAWKVVNKIDN
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GNKSCEQLIREALQILSSR
CCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA