Click here to switch to the map view.

The map label for this gene is surE

Identifier: 54297200

GI number: 54297200

Start: 1382753

End: 1383511

Strand: Direct

Name: surE

Synonym: lpp1245

Alternate gene names: 54297200

Gene position: 1382753-1383511 (Clockwise)

Preceding gene: 54297199

Following gene: 54297201

Centisome position: 39.47

GC content: 38.21

Gene sequence:

>759_bases
ATGAAAATATTAGTAAGCAATGATGACGGGGTTTTGGCGCCCGGGATCAAAATTTTAGCTAATGAGCTGTCCACTTTAGG
AGAAGTTAAAGTGGTTGCGCCTGATAGAAATAGAAGTGGCGCCAGTAATTCTTTGACTTTAACACAACCTTTGAGAGTTA
AACAATTGGACAATGGTTATTATAGTGTGGATGGAACACCTACTGATTGCGTCCATCTGGCGTTAACCGGATTTTTAGAG
CCTATAGCAGACATAGTCGTTTCAGGGATTAATGAGGGTGCCAATTTAGGGGATGATGTACTTTACTCAGGTACAGTGGC
AGCGGCTATGGAAGGTCGTTATTTAGGGTTGCCTGCTATTGCAATCTCAATGGTAGGAGACAACATACAATATTATGAAA
CAGCTGCAATTATTGCCAAACAATTGGTTATAAAATTAAGTGCTAACAAATTACCTTCTCAGACTATATTAAATGTTAAT
GTTCCTGATTTACCTTTGAGTCAAATAAGAGGATTGCAGGTTACGCGATTGGGAACTCGTCATAGTGCTGAGCCTATTAT
TAAAGAATATGATCCCAGAGGAAGGCCAATTTATTGGGTTGGTCCACCGGGTATAGAAGCAGATGCTGGTGCTGGTACTG
ATTTTTTTGCAATTAAAACAGGTCATGTTTCTATAACACCGCTTCATTTAGACATGACTCATTATAAGTTATTTGATCAT
TTATCTAACTTGCTTAACGAAATTTGCATAGAAAATTAA

Upstream 100 bases:

>100_bases
AGGATAACGCTGAATTACAAGATTCATTGAAAAGAAATCAAGAAGATCTTGCTTACTATTTAGCAGTTGTAAAATGGTTA
GAATCCCCTGAGAGTTAAAC

Downstream 100 bases:

>100_bases
TAAATAATAAATGAGATAATGATGCGCCTATTTCGCAAACAATTAATTTGTATTTTTTTTATCTTAAGTGTTGCTGGTTG
TGGGACAAGAAGTGATTTGG

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKILVSNDDGVLAPGIKILANELSTLGEVKVVAPDRNRSGASNSLTLTQPLRVKQLDNGYYSVDGTPTDCVHLALTGFLE
PIADIVVSGINEGANLGDDVLYSGTVAAAMEGRYLGLPAIAISMVGDNIQYYETAAIIAKQLVIKLSANKLPSQTILNVN
VPDLPLSQIRGLQVTRLGTRHSAEPIIKEYDPRGRPIYWVGPPGIEADAGAGTDFFAIKTGHVSITPLHLDMTHYKLFDH
LSNLLNEICIEN

Sequences:

>Translated_252_residues
MKILVSNDDGVLAPGIKILANELSTLGEVKVVAPDRNRSGASNSLTLTQPLRVKQLDNGYYSVDGTPTDCVHLALTGFLE
PIADIVVSGINEGANLGDDVLYSGTVAAAMEGRYLGLPAIAISMVGDNIQYYETAAIIAKQLVIKLSANKLPSQTILNVN
VPDLPLSQIRGLQVTRLGTRHSAEPIIKEYDPRGRPIYWVGPPGIEADAGAGTDFFAIKTGHVSITPLHLDMTHYKLFDH
LSNLLNEICIEN
>Mature_252_residues
MKILVSNDDGVLAPGIKILANELSTLGEVKVVAPDRNRSGASNSLTLTQPLRVKQLDNGYYSVDGTPTDCVHLALTGFLE
PIADIVVSGINEGANLGDDVLYSGTVAAAMEGRYLGLPAIAISMVGDNIQYYETAAIIAKQLVIKLSANKLPSQTILNVN
VPDLPLSQIRGLQVTRLGTRHSAEPIIKEYDPRGRPIYWVGPPGIEADAGAGTDFFAIKTGHVSITPLHLDMTHYKLFDH
LSNLLNEICIEN

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=251, Percent_Identity=56.5737051792829, Blast_Score=285, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_LEGPA (Q5X5S5)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123569.1
- ProteinModelPortal:   Q5X5S5
- SMR:   Q5X5S5
- STRING:   Q5X5S5
- GeneID:   3116521
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1245
- LegioList:   lpp1245
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   LPNE297246:LPP1245-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27054; Mature: 27054

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVSNDDGVLAPGIKILANELSTLGEVKVVAPDRNRSGASNSLTLTQPLRVKQLDNGY
CEEEEECCCCEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCEEEEECCCE
YSVDGTPTDCVHLALTGFLEPIADIVVSGINEGANLGDDVLYSGTVAAAMEGRYLGLPAI
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCEEEEHCCCCEECCHHH
AISMVGDNIQYYETAAIIAKQLVIKLSANKLPSQTILNVNVPDLPLSQIRGLQVTRLGTR
EEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHCCEEEEECCCC
HSAEPIIKEYDPRGRPIYWVGPPGIEADAGAGTDFFAIKTGHVSITPLHLDMTHYKLFDH
CCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEEEEEECHHHHHHHHH
LSNLLNEICIEN
HHHHHHHHHCCC
>Mature Secondary Structure
MKILVSNDDGVLAPGIKILANELSTLGEVKVVAPDRNRSGASNSLTLTQPLRVKQLDNGY
CEEEEECCCCEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCEEEEECCCE
YSVDGTPTDCVHLALTGFLEPIADIVVSGINEGANLGDDVLYSGTVAAAMEGRYLGLPAI
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCEEEEHCCCCEECCHHH
AISMVGDNIQYYETAAIIAKQLVIKLSANKLPSQTILNVNVPDLPLSQIRGLQVTRLGTR
EEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHCCEEEEECCCC
HSAEPIIKEYDPRGRPIYWVGPPGIEADAGAGTDFFAIKTGHVSITPLHLDMTHYKLFDH
CCCCCHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEEEEEECHHHHHHHHH
LSNLLNEICIEN
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA