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The map label for this gene is hbpA [H]

Identifier: 54296980

GI number: 54296980

Start: 1138665

End: 1140821

Strand: Direct

Name: hbpA [H]

Synonym: lpp1021

Alternate gene names: 54296980

Gene position: 1138665-1140821 (Clockwise)

Preceding gene: 54296979

Following gene: 54296981

Centisome position: 32.5

GC content: 38.11

Gene sequence:

>2157_bases
ATGATATTTTTAATGCCTTGCTGTGTCAATTTGGCTTATGGCAGTCCTTGGGTATTCAATAATCCTTACCCAGAGAGCGA
GGCCAATGAAAATATTTATTATTCTTCTTTTAATGAACAGCCAAAAACTCTGGATCCGGCACGTTCCTATTCTTCCAATG
AATATCTTTTCATAGCCCAGATCTATGAGCCACTGCTGGAATATGATTACTATAAAAGACCCTATGAATTAATCCCATTA
ACAGCTACCCGCTTACCACAGATTCGATATTTGGATGCCCAGGGAAATCCTGTTCCGGCAGGAGATAACACAAAGCCAGC
ATACAGTGTCTATACCATTCAGATAAAAAAAGGCATTTTATATCAGCCTCATCCTGCTTTGGCTCAGAAGAAAGATGGCT
CTTATCGATATCATCACTTACCAGAAGATTATTTGGAAAAGCATGATATTAGCAAGTTGTCAGATTTTAAATACACCGGT
ACAAGGGAGCTGATCATTGATGATTACATTTATCAAATTAAAAGATTGGCAAACCCTGCTGTGAGTTCTCCGATATATGG
ATTGATGAGCTATTATATTCTGGGCTTCAAGGAGTATGGAGATAGTCTTCCTAAAGGATTGACCAATAAAAATTCTTTTA
TTGATTTACGTAAGTATCCTTTGAAGGGGGTTAAAAAATTAGATGATTACACCTTTGAGATTACATTAAAGGGACAATAT
ACACAATTTTTGTTTTGGTTAGCCATGCCCTTTTTTGCTCCGGTTCCATGGGAAGCGGATTTATTTTATTCCCAAAAAGA
TATGGATGATAAGAACTTATCTTTTAGCTGGTATCCTATAGGTACAGGGCCTTTTATGCTGACTGAAAATAATCCCAATA
GAAGCATGATATTGGAGAAAAATCCTAATTTCAGAGAAGTGTATTTTCCTGTCAATGGTTCAGATGCCGATAGACGGGCA
GGTTATTTAACCAACCAGGGAAGGCGCTTGCCCTTAATTGATAAAGCCGTTTATACCCTTGAAAAGGAATCCATACCTCG
ATGGAATAAATTCTTGCAAGGCTACTATGATATGTCGGGGATAAGTGCTGACAGTTTTGATCAGGCTATCCATATTAATC
GCTTTGGAGAGCCTATCCTTAGCCAGGAAATGAAAGATAAAAAAATATATTTAAGACAAACCCTGGAACCGTCTATCTAT
TATACTGGCTTTAATATGCTTGACAGCGTTGTTGGGGGCAATAGCAAAAGAGCACGAAAATTACGCCAGGCAATTTCTAT
TGCGGTGAATTTTGATGAAAATATTGCCATATTTTTTAATGGCCGAGGTATTCCGGCGCAAGGCCCTATTCCACCTGGTA
TCTTTGGGTACAAGGAAGGAAAAGAGGGTATTAATCCCTATGTTTATCAATGGGTGAATAATGCGAGGAAGCGAAAATCC
TTAAAGGATGCGCAGAAGTTAATGGTTGAGGCAGGATATCCGGGTGGGATAGATCCGAAAACCGGGAAACACCTGATTCT
TCATTATGATGTCATGACGACAGGTGGACCTGATGACAAAGCAAGGCTTGACTGGATGCGAAAGCAATTCGCAAATATAG
GGATAGATTTGAATATTAGGGCGACTCTTTACAATCGTTTCCAGGAAAAGATGCGGATAGGTCATGCTCAAATATTTAGT
TGGGGCTGGAATGCCGATTATCCTGATCCCGAAAATTTTTTATTTTTGCTTTATGGGAAAAATGGAAAAGTGAAGTATGG
TGGTGAAAATGCATCAAATTATGAAAATCCTGAATTTGATAGATTGTTTAATTTGATGAAAAATCGCCCTAACGATCTAC
AAAGACAAAAACTGATTGATAAGATGTTAGCGATTGTCCGGTATGATGCTCCATGGGTATGGGGCATGCATTCTGAAGAC
TTTATTTTATCGCAAGATTGGGTATCTAATATAAAATCCAATACGATTTCTCTCAATACTCTAAAATATGTTTCTGTTAA
TGTACCTGAACGTAACCAGCTGCGAAGATCCTGGAATCAACCGGTATTTTGGCCTTTAGGTGTGCTGTTTGGCCTATTGA
TTGCTCTGGTAATCCCTTTATTGATTACTTATTTAAAGAAAGAAAAACAGCCGGCAGAAAGAGTAAAATTAAAATGA

Upstream 100 bases:

>100_bases
GATGGGTATCAATGAATCGGGTGAAGTAGGTATTTAAACCTGTAATAATGACTGATTGGCACGAGGGAAGTAAGTGCGGC
GATATTTGTTAATGCAATTC

Downstream 100 bases:

>100_bases
TTAAATACATACTCCGCAGAATTTTATATGCGATTCCAATTTTGTTTGGTATTAATCTTATTACTTTTGCATTGTTTTTC
ATGGTTAATTCTCCCGATGA

Product: hypothetical protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MIFLMPCCVNLAYGSPWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYELIPL
TATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEKHDISKLSDFKYTG
TRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLTNKNSFIDLRKYPLKGVKKLDDYTFEITLKGQY
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFSWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPVNGSDADRRA
GYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIY
YTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQIFS
WGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSED
FILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK

Sequences:

>Translated_718_residues
MIFLMPCCVNLAYGSPWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYELIPL
TATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEKHDISKLSDFKYTG
TRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLTNKNSFIDLRKYPLKGVKKLDDYTFEITLKGQY
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFSWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPVNGSDADRRA
GYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIY
YTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQIFS
WGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSED
FILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK
>Mature_718_residues
MIFLMPCCVNLAYGSPWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQIYEPLLEYDYYKRPYELIPL
TATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGILYQPHPALAQKKDGSYRYHHLPEDYLEKHDISKLSDFKYTG
TRELIIDDYIYQIKRLANPAVSSPIYGLMSYYILGFKEYGDSLPKGLTNKNSFIDLRKYPLKGVKKLDDYTFEITLKGQY
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFSWYPIGTGPFMLTENNPNRSMILEKNPNFREVYFPVNGSDADRRA
GYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSGISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIY
YTGFNMLDSVVGGNSKRARKLRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIRATLYNRFQEKMRIGHAQIFS
WGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFDRLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSED
FILSQDWVSNIKSNTISLNTLKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=531, Percent_Identity=23.9171374764595, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 83305; Mature: 83305

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLMPCCVNLAYGSPWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQ
CEEEEEEHHECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCEEEEHH
IYEPLLEYDYYKRPYELIPLTATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGIL
HHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCE
YQPHPALAQKKDGSYRYHHLPEDYLEKHDISKLSDFKYTGTRELIIDDYIYQIKRLANPA
ECCCCHHHCCCCCCEEECCCCHHHHHHHCHHHHHCCCCCCCHHEEHHHHHHHHHHHCCCC
VSSPIYGLMSYYILGFKEYGDSLPKGLTNKNSFIDLRKYPLKGVKKLDDYTFEITLKGQY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHCCCHHHHHCCCEEEEEEECCCH
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFSWYPIGTGPFMLTENNPNRSMILEK
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEEEC
NPNFREVYFPVNGSDADRRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSG
CCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
ISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVVGGNSKRARK
CCCCCHHCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCHHHHHH
LRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
HHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIR
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEH
ATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFD
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCHH
RLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSEDFILSQDWVSNIKSNTISLNT
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECHHHHHHHCCCEEEEEE
LKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK
EEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
>Mature Secondary Structure
MIFLMPCCVNLAYGSPWVFNNPYPESEANENIYYSSFNEQPKTLDPARSYSSNEYLFIAQ
CEEEEEEHHECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCEEEEHH
IYEPLLEYDYYKRPYELIPLTATRLPQIRYLDAQGNPVPAGDNTKPAYSVYTIQIKKGIL
HHHHHHHHHHHCCCCEEEEECHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCE
YQPHPALAQKKDGSYRYHHLPEDYLEKHDISKLSDFKYTGTRELIIDDYIYQIKRLANPA
ECCCCHHHCCCCCCEEECCCCHHHHHHHCHHHHHCCCCCCCHHEEHHHHHHHHHHHCCCC
VSSPIYGLMSYYILGFKEYGDSLPKGLTNKNSFIDLRKYPLKGVKKLDDYTFEITLKGQY
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHCCCHHHHHCCCEEEEEEECCCH
TQFLFWLAMPFFAPVPWEADLFYSQKDMDDKNLSFSWYPIGTGPFMLTENNPNRSMILEK
HHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCEEEEEC
NPNFREVYFPVNGSDADRRAGYLTNQGRRLPLIDKAVYTLEKESIPRWNKFLQGYYDMSG
CCCCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
ISADSFDQAIHINRFGEPILSQEMKDKKIYLRQTLEPSIYYTGFNMLDSVVGGNSKRARK
CCCCCHHCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCHHHHHH
LRQAISIAVNFDENIAIFFNGRGIPAQGPIPPGIFGYKEGKEGINPYVYQWVNNARKRKS
HHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LKDAQKLMVEAGYPGGIDPKTGKHLILHYDVMTTGGPDDKARLDWMRKQFANIGIDLNIR
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEH
ATLYNRFQEKMRIGHAQIFSWGWNADYPDPENFLFLLYGKNGKVKYGGENASNYENPEFD
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCHH
RLFNLMKNRPNDLQRQKLIDKMLAIVRYDAPWVWGMHSEDFILSQDWVSNIKSNTISLNT
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECHHHHHHHCCCEEEEEE
LKYVSVNVPERNQLRRSWNQPVFWPLGVLFGLLIALVIPLLITYLKKEKQPAERVKLK
EEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]