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The map label for this gene is coaX

Identifier: 54296932

GI number: 54296932

Start: 1077494

End: 1078264

Strand: Direct

Name: coaX

Synonym: lpp0973

Alternate gene names: 54296932

Gene position: 1077494-1078264 (Clockwise)

Preceding gene: 54296931

Following gene: 54296933

Centisome position: 30.75

GC content: 38.13

Gene sequence:

>771_bases
ATGATTCTGTGTATTGATGTAGGAAACTCTCATATATATGGTGGAGTATTTGATGGAGATGAGATTAAGCTCCGGTTTCG
TCATACTTCCAAGGTAAGTACTTCGGATGAATTGGGTATCTTTCTTAAAAGTGTTTTACGTGAAAACAATTGCTCTCCTG
AGACAATTAGAAAAATTGCTATTTGTTCAGTAGTACCTCAAGTGGATTACTCATTGCGGTCTGCCTGTGTGAAGTATTTT
TCAATTGACCCGTTTTTATTACAGGCAGGGGTTAAGACTGGATTGAATATCAAATATAGAAATCCGGTTGAGGTTGGAGC
TGACCGAATTGCGAATGCTATTGCCGCCACTCATAGTTTCCCTAATCAAAACATTATTGTTATTGATTTTGGTACAGCAA
CTACTTTTTGTGCCATTTCTCATAAAAAAGCTTATTTAGGTGGTGCTATTTTGCCAGGCCTTAGATTATCTGCTGATGCT
TTGTCAAAAAATACTGCAAAGTTACCTTCTGTTGAAATTATCAAGACCGAGAGTGTAGTTGGGCGTTCTACCATAGAAAG
CATTCAGTCTGGAGTCTACTATGGTGTCCTTGGTGCATGTAAAGAATTAATTCAAAGAATACATCATGAAGCGTTCAATG
GCGATCAAATACTAATTTTGGCAACAGGGGGATTTGCGTCTTTATTTGATAAACAAGGTCTTTATGACCATCTTGTCCCA
GATTTGGTTCTCCAGGGGATAAGATTGGCTGCTATGATGAATACTGCCTGA

Upstream 100 bases:

>100_bases
TCTCAATACAAGTCTATTTCTTTCCGGGATTGCTGAATTATTGTCTTAGACCTATAATCACAAATCACCAATTATGCCAT
TTAAAAAGTAGATCTTAATA

Downstream 100 bases:

>100_bases
GCAGTAAAAGGTTTTTGTTAATATCAGAGTGATTTCTGTTTATTCTCATGGAGTTTATGGGGTGTTTCGTATTCTGGTAA
GTTAATCAAAAGGGAGGATT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIAICSVVPQVDYSLRSACVKYF
SIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSFPNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADA
LSKNTAKLPSVEIIKTESVVGRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDQILILATGGFASLFDKQGLYDHLVP
DLVLQGIRLAAMMNTA

Sequences:

>Translated_256_residues
MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIAICSVVPQVDYSLRSACVKYF
SIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSFPNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADA
LSKNTAKLPSVEIIKTESVVGRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDQILILATGGFASLFDKQGLYDHLVP
DLVLQGIRLAAMMNTA
>Mature_256_residues
MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIAICSVVPQVDYSLRSACVKYF
SIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSFPNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADA
LSKNTAKLPSVEIIKTESVVGRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDQILILATGGFASLFDKQGLYDHLVP
DLVLQGIRLAAMMNTA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_LEGPA (Q5X6J2)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123301.1
- ProteinModelPortal:   Q5X6J2
- SMR:   Q5X6J2
- STRING:   Q5X6J2
- GeneID:   3116447
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0973
- LegioList:   lpp0973
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- BioCyc:   LPNE297246:LPP0973-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27744; Mature: 27744

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: ACT_SITE 108-108 BINDING 99-99 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIA
CEEEEEECCCEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
ICSVVPQVDYSLRSACVKYFSIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSF
HHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCC
PNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADALSKNTAKLPSVEIIKTESVV
CCCCEEEEECCCCCEEEEECCCHHHHCCHHCCCCEECHHHHCCCCCCCCCEEEEECCHHH
GRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDQILILATGGFASLFDKQGLYDHLVP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHCCCCHHHHHH
DLVLQGIRLAAMMNTA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILCIDVGNSHIYGGVFDGDEIKLRFRHTSKVSTSDELGIFLKSVLRENNCSPETIRKIA
CEEEEEECCCEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
ICSVVPQVDYSLRSACVKYFSIDPFLLQAGVKTGLNIKYRNPVEVGADRIANAIAATHSF
HHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCC
PNQNIIVIDFGTATTFCAISHKKAYLGGAILPGLRLSADALSKNTAKLPSVEIIKTESVV
CCCCEEEEECCCCCEEEEECCCHHHHCCHHCCCCEECHHHHCCCCCCCCCEEEEECCHHH
GRSTIESIQSGVYYGVLGACKELIQRIHHEAFNGDQILILATGGFASLFDKQGLYDHLVP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHCCCCHHHHHH
DLVLQGIRLAAMMNTA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA