Click here to switch to the map view.

The map label for this gene is mreB [H]

Identifier: 54296832

GI number: 54296832

Start: 982548

End: 983585

Strand: Direct

Name: mreB [H]

Synonym: lpp0873

Alternate gene names: 54296832

Gene position: 982548-983585 (Clockwise)

Preceding gene: 54296831

Following gene: 54296833

Centisome position: 28.04

GC content: 44.99

Gene sequence:

>1038_bases
ATGTTCAGGAAATTAAGAGGCGTGTTTTCTAGCGATTTGTCAATCGATTTGGGAACAGCTAATACATTGATTTACGTAAG
AGATAAGGGGATTGTTCTCAATGAACCTTCTGTAGTGGCATTGCGTAATGAATCAGGCCAGAAGCGTGTCGCCGCTGTAG
GTCTTGAAGCCAAACGCATGTTGGGAAGAACCCCTGGCAATATTAATGCGATAAGACCCATGAAAGATGGGGTTATTGCT
GACTTTTTTGTCACCGAGAAAATGTTGCAGCACTTTATACACAAAGTGCATGAAAATAAATTTTTACGACCCAGTCCACG
AGTTTTGGTCTGTGTTCCTTGTGGTTCTACACAAGTGGAACGCAGAGCAATTCGTGAATCTGCAATGGGCGCTGGTGCTC
GAGAAGTTTTCCTTATTGAGGAGCCTATGGCTGCGGCATTAGGTTCCGGAATGCCTGTTGAGGAAGCCAGTGGTTCTATG
GTGGTTGATATAGGCGGTGGTACCACAGAAGTCGCAATTATTTCACTAAGTGGAATAGTTTATCATCAATCAGTACGTAT
TGGTGGCGATAAATTTGATGACGCAATCGTATCCTACGTACGCCGTAATTATGGTACTCTCATCGGAGAAACAACCGCTG
AACGCATTAAACATGAAATTGGTTCGGCTTTCCCAAGCCGGGATTTATTTGAGATCGAGGTACGAGGTAGAAATCTTGCG
GAAGGTGTACCACGTAGCTTTACTTTAACAAGCGCTGAAATCCTGGAAGCACTACAGGAACCTCTATCGGGGATAGTTGG
TGCGGTTCGAGCTGCTTTGGAGCTTGCTCCGCCTGAGTTGGCTGCAGATATTGCTGAAAGAGGTATGGTTTTAACAGGCG
GAGGCGCTCTGTTGAAAAATATAGACACCTTGTTGATGGAAGAAACTGGATTACCCGTATTAATAGCTGAAGATCCATTA
ACCTGCGTTGCGCGTGGTGGTGGTAAAGCTTTAGAAACCATGGATTTGCGCGGCGGTGATTTCCTCTCAACAGAATAA

Upstream 100 bases:

>100_bases
GCAGTTGTCTGGTGTATAAAATTCTTATGCGGCAACTGTCGATTTTTATCCAAATATAGGATAAAGTAGCAATCAAAAAA
ACAACGGGGTAGTACTGCGT

Downstream 100 bases:

>100_bases
TAAACACAATAGATTATTTGCAAAGGGCGGACACAGTTCTCTGGGATTTGTGTTTGCCCTTGCTTTTTCTATTCTCCTGA
TGTTTTCTGATTATCATTAC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRMLGRTPGNINAIRPMKDGVIA
DFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSM
VVDIGGGTTEVAIISLSGIVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRNLA
EGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKNIDTLLMEETGLPVLIAEDPL
TCVARGGGKALETMDLRGGDFLSTE

Sequences:

>Translated_345_residues
MFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRMLGRTPGNINAIRPMKDGVIA
DFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSM
VVDIGGGTTEVAIISLSGIVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRNLA
EGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKNIDTLLMEETGLPVLIAEDPL
TCVARGGGKALETMDLRGGDFLSTE
>Mature_345_residues
MFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRMLGRTPGNINAIRPMKDGVIA
DFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSM
VVDIGGGTTEVAIISLSGIVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRNLA
EGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKNIDTLLMEETGLPVLIAEDPL
TCVARGGGKALETMDLRGGDFLSTE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=78.3861671469741, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36954; Mature: 36954

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRM
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCEEEEECHHHHHH
LGRTPGNINAIRPMKDGVIADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVE
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHH
RRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSMVVDIGGGTTEVAIISLSGIV
HHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEECEE
YHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRNLA
EEEEEEECCCHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
EGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKN
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHHHH
IDTLLMEETGLPVLIAEDPLTCVARGGGKALETMDLRGGDFLSTE
HHHHHHHCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRM
CCHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCEEEEECHHHHHH
LGRTPGNINAIRPMKDGVIADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVE
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHH
RRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSMVVDIGGGTTEVAIISLSGIV
HHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEECEE
YHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRNLA
EEEEEEECCCHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
EGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKN
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHHHH
IDTLLMEETGLPVLIAEDPLTCVARGGGKALETMDLRGGDFLSTE
HHHHHHHCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]