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The map label for this gene is aspC [H]

Identifier: 54027401

GI number: 54027401

Start: 5744689

End: 5745942

Strand: Reverse

Name: aspC [H]

Synonym: nfa54270

Alternate gene names: 54027401

Gene position: 5745942-5744689 (Counterclockwise)

Preceding gene: 54027402

Following gene: 54027400

Centisome position: 95.43

GC content: 65.31

Gene sequence:

>1254_bases
ATGGGACACGTGAGTCCTCATCTTCCGCATCGCCCGCCGCGCGTTCTGGAGCAGTCCACGAAGCTCCAGAACGTCGTCTA
CGAAATTCGTGGACCGGTACACGCGCACGCGGCACGGCTGGAGGCGGAGGGGCATCGCATCCTCAAGCTCAACATCGGCA
ATCCCGCGCCGTTCGGCTTCGAGGCGCCCGATGTGATCATGCGCGACATCATCGCCGCGCTGCCGTATGCGCAGGGCTAC
TCGGAGTCCAAGGGCATCCTGTCGGCGCGGCGGGCCATCGTCACCCGCTACGAGCTGGTGCCGGGTTTCCCCGAGTTCGA
TGTCGACGACGTCTACCTCGGTAACGGCGTCTCCGAGCTGATCACGCTCACCATGCAGGCGCTGCTCGACAACGGTGACG
AGGTGCTCATCCCCGCGCCGGACTACCCGCTGTGGACGGCGATGACCAGCCTCGCCGGTGGCACGCCCGTGCACTACCTG
TGCGACGAGTCCAACGGCTGGCAGCCCGACATCGCCGACATCGAAGCCAAGATCACCGACAAGACCAAGGCCCTGCTGGT
GATCAACCCGAACAATCCGACCGGGGCGGTGTACTCGGCGGAGGTGTTGCAGCAGATCGTCGACCTCGCCCGTAAGCATC
AGCTGCTGCTGCTGGCCGACGAGATCTACGACAAGATCCTCTACGACGACGCCAAGCACATCTCGCTGGCCACGCTGGCC
CCCGACCTGCTGTGCCTGACCTTCAACGGGCTGTCCAAGGCCTACCGGGTGGCGGGGTATCGGTCCGGCTGGATGGTCAT
CACCGGTCCGAAGGAGCACGCGACGGGGTTCCTGGAGGGCATCGACCTGCTCGCCACCTCCCGGCTGTGCCCGAATGTGC
CCGCGCAGCACGCGATTCAGGTCGCGCTCGGCGGCCATCAGAGCATCGAGGACCTGATCCTGCCCGGCGGCCGGTTGCTC
GAGCAGCGTGATGTCGCTTGGGAGCGGCTGAACATGATTCCCGGTGTGTCCTGTGTGAAGCCCAAGGGCGCGCTCTACGC
CTTCCCGCGGTTGGACCCCGAGGTCTACGAGATCCACGACGACTCGAAGCTGATCCTGGATCTGCTGCTGCAGGAGAAGA
TCCTGATGGTGCAGGGCACCGGGTTCAACTGGCCCGCCCACGATCACCTGCGCATCGTGACGCTGCCCTGGGCGCGCGAT
CTGGCGGTGGCGATCGAACGGTTCGGCAACTTCCTGGCCAGCTATCGTCAGTGA

Upstream 100 bases:

>100_bases
GGCGGCCAAGGGCATGCCCACGGGCGGCGCCTCGATCGGCGCGTGAGTACCGACACTGCCGTCGACCTCGGCAAATAATC
GGCTTGCCGGAGATGGCACC

Downstream 100 bases:

>100_bases
GTGAGGTCCGGAATCGCCCCGGTTCCGGACCTGAAACATACCGCGTGTACGAATACCTGCGAGTTTTACAGATGGCCTAG
CGCAAAACGGGAAGTTTTGT

Product: aminotransferase AlaT

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MGHVSPHLPHRPPRVLEQSTKLQNVVYEIRGPVHAHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIAALPYAQGY
SESKGILSARRAIVTRYELVPGFPEFDVDDVYLGNGVSELITLTMQALLDNGDEVLIPAPDYPLWTAMTSLAGGTPVHYL
CDESNGWQPDIADIEAKITDKTKALLVINPNNPTGAVYSAEVLQQIVDLARKHQLLLLADEIYDKILYDDAKHISLATLA
PDLLCLTFNGLSKAYRVAGYRSGWMVITGPKEHATGFLEGIDLLATSRLCPNVPAQHAIQVALGGHQSIEDLILPGGRLL
EQRDVAWERLNMIPGVSCVKPKGALYAFPRLDPEVYEIHDDSKLILDLLLQEKILMVQGTGFNWPAHDHLRIVTLPWARD
LAVAIERFGNFLASYRQ

Sequences:

>Translated_417_residues
MGHVSPHLPHRPPRVLEQSTKLQNVVYEIRGPVHAHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIAALPYAQGY
SESKGILSARRAIVTRYELVPGFPEFDVDDVYLGNGVSELITLTMQALLDNGDEVLIPAPDYPLWTAMTSLAGGTPVHYL
CDESNGWQPDIADIEAKITDKTKALLVINPNNPTGAVYSAEVLQQIVDLARKHQLLLLADEIYDKILYDDAKHISLATLA
PDLLCLTFNGLSKAYRVAGYRSGWMVITGPKEHATGFLEGIDLLATSRLCPNVPAQHAIQVALGGHQSIEDLILPGGRLL
EQRDVAWERLNMIPGVSCVKPKGALYAFPRLDPEVYEIHDDSKLILDLLLQEKILMVQGTGFNWPAHDHLRIVTLPWARD
LAVAIERFGNFLASYRQ
>Mature_416_residues
GHVSPHLPHRPPRVLEQSTKLQNVVYEIRGPVHAHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIAALPYAQGYS
ESKGILSARRAIVTRYELVPGFPEFDVDDVYLGNGVSELITLTMQALLDNGDEVLIPAPDYPLWTAMTSLAGGTPVHYLC
DESNGWQPDIADIEAKITDKTKALLVINPNNPTGAVYSAEVLQQIVDLARKHQLLLLADEIYDKILYDDAKHISLATLAP
DLLCLTFNGLSKAYRVAGYRSGWMVITGPKEHATGFLEGIDLLATSRLCPNVPAQHAIQVALGGHQSIEDLILPGGRLLE
QRDVAWERLNMIPGVSCVKPKGALYAFPRLDPEVYEIHDDSKLILDLLLQEKILMVQGTGFNWPAHDHLRIVTLPWARDL
AVAIERFGNFLASYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=471, Percent_Identity=26.5392781316348, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI4507369, Length=363, Percent_Identity=30.0275482093664, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=28.5326086956522, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4885351, Length=436, Percent_Identity=26.3761467889908, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI95147551, Length=163, Percent_Identity=35.5828220858896, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI169881279, Length=163, Percent_Identity=35.5828220858896, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI56713254, Length=158, Percent_Identity=36.0759493670886, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI56713256, Length=158, Percent_Identity=36.0759493670886, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169881281, Length=148, Percent_Identity=33.7837837837838, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI149944424, Length=340, Percent_Identity=22.6470588235294, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788627, Length=402, Percent_Identity=63.681592039801, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=27.1573604060914, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786816, Length=242, Percent_Identity=25.2066115702479, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=410, Percent_Identity=29.2682926829268, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71981209, Length=484, Percent_Identity=24.7933884297521, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=152, Percent_Identity=35.5263157894737, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=152, Percent_Identity=35.5263157894737, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71981215, Length=310, Percent_Identity=26.1290322580645, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=204, Percent_Identity=30.3921568627451, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=479, Percent_Identity=26.9311064718163, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=486, Percent_Identity=26.9547325102881, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=238, Percent_Identity=27.3109243697479, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859735, Length=372, Percent_Identity=26.8817204301075, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24641770, Length=463, Percent_Identity=27.2138228941685, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24641760, Length=463, Percent_Identity=27.2138228941685, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24641768, Length=463, Percent_Identity=27.2138228941685, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24641766, Length=463, Percent_Identity=27.2138228941685, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24641764, Length=463, Percent_Identity=27.2138228941685, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI45551451, Length=463, Percent_Identity=27.2138228941685, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28573069, Length=295, Percent_Identity=25.7627118644068, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24646114, Length=295, Percent_Identity=25.7627118644068, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28573067, Length=295, Percent_Identity=25.7627118644068, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28573065, Length=295, Percent_Identity=25.7627118644068, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 46094; Mature: 45962

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHVSPHLPHRPPRVLEQSTKLQNVVYEIRGPVHAHAARLEAEGHRILKLNIGNPAPFGF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCC
EAPDVIMRDIIAALPYAQGYSESKGILSARRAIVTRYELVPGFPEFDVDDVYLGNGVSEL
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHH
ITLTMQALLDNGDEVLIPAPDYPLWTAMTSLAGGTPVHYLCDESNGWQPDIADIEAKITD
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCEEEEEC
KTKALLVINPNNPTGAVYSAEVLQQIVDLARKHQLLLLADEIYDKILYDDAKHISLATLA
CCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCEEEHHHC
PDLLCLTFNGLSKAYRVAGYRSGWMVITGPKEHATGFLEGIDLLATSRLCPNVPAQHAIQ
CCEEEEEEHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEE
VALGGHQSIEDLILPGGRLLEQRDVAWERLNMIPGVSCVKPKGALYAFPRLDPEVYEIHD
EEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCEEECCCCCCCEEEECC
DSKLILDLLLQEKILMVQGTGFNWPAHDHLRIVTLPWARDLAVAIERFGNFLASYRQ
CHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GHVSPHLPHRPPRVLEQSTKLQNVVYEIRGPVHAHAARLEAEGHRILKLNIGNPAPFGF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCC
EAPDVIMRDIIAALPYAQGYSESKGILSARRAIVTRYELVPGFPEFDVDDVYLGNGVSEL
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHH
ITLTMQALLDNGDEVLIPAPDYPLWTAMTSLAGGTPVHYLCDESNGWQPDIADIEAKITD
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCEEEEEC
KTKALLVINPNNPTGAVYSAEVLQQIVDLARKHQLLLLADEIYDKILYDDAKHISLATLA
CCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCEEEHHHC
PDLLCLTFNGLSKAYRVAGYRSGWMVITGPKEHATGFLEGIDLLATSRLCPNVPAQHAIQ
CCEEEEEEHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEE
VALGGHQSIEDLILPGGRLLEQRDVAWERLNMIPGVSCVKPKGALYAFPRLDPEVYEIHD
EEECCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCEEECCCCCCCEEEECC
DSKLILDLLLQEKILMVQGTGFNWPAHDHLRIVTLPWARDLAVAIERFGNFLASYRQ
CHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]