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The map label for this gene is mas [H]

Identifier: 54027327

GI number: 54027327

Start: 5659068

End: 5660099

Strand: Reverse

Name: mas [H]

Synonym: nfa53530

Alternate gene names: 54027327

Gene position: 5660099-5659068 (Counterclockwise)

Preceding gene: 54027328

Following gene: 54027326

Centisome position: 94.0

GC content: 71.51

Gene sequence:

>1032_bases
ATGATCACCACAGCCACCGAAATCGTGCTGCCCGGCCGCGTCGAGCCGGACGGACTGCTCGTCACCCGGCGCGAGCTGCC
CGCGCCGGGCCCCGGCCAGGCGCTCGTGCGGGTCGAGGCGAGCGGCGTCTCCTTCGCCGAGCAGCAGATGCGACGCGGCA
AGTACTACGACCAGCCACCGTTCCCGTTCGTGCCCGGCTACGACCTGGTCGGCATCGTCACCGCGGTGGGCCAGGACGTC
GATGCCGCGCTGGTGGGACGCCGGGTGGCGGCGCTGACCAAGATCGGCGGCTGGACCAGCGCCGCCCTGCTGGACGCCGC
CGACCTGGTGCCCGTGCCGGAGCCACTCGACGCCGCCGCGGCCGAGACCTTCGTCGTCAACGGGATCACCGCGTGGCAGA
TGCTGTTCCGCACCGCGAAAGTCCGTGCCGGACAGACCATCCTGGTGCACGGCGCGAACGGCGGGGTCGGATCGACCCTC
GTCCAGCTGGCGCGCGCCCACGGCATCCATGTCATCGGCACGGCCTCGGCGCGCCACCGCCGCGCCGTCGAGGAACTCGG
CGCGACCTGGATCGACTATCGCACCGACGTGGCACGGCAGGTACGGGAGCTGGCGCCGGGCGGGGTGAACGCGGTGTTCG
ACCACATCGGCGGTCCCGGCATCGTCGAGTCGTTCCGCTTGCTCGCCCCGCACGGCACCCTGGTCTCCTACGGCACCGCC
GCAACCAAGGACCAGGAGGGCAATTCCCGGCTGCCGGTGTTGACGCTGCTCGCGCGGTTGGTGCTGTGGAACGCGCTGCC
CAACAAGCGAAATGCGCACTTCTTCAATCTGTGGGCGGGTAAGCGCAACCTGTCGCGCTTCCGCGCCCGGATCGCCGCGG
ACCTCGGCGCCGTCTTCGACCTCGCGGCACAGGGCGTACTGCGCGCCCAGGTCGCGGCCCGGGTTCCGTTGAGCGCGGCG
GCCCGCGCGGTCGAGCTCGCCGAATCCGGTTCCGTCGTCGGCAAAGTCGTTCTCGTCGCCGACGAAGGCTGA

Upstream 100 bases:

>100_bases
GGGCATCCGGCACCCCGGCTGACCCGTTCCGACCATGCCCCTTCGGGGGCTTTTCTTCGACCCATCGAGTGATTGACCAG
TCACACACTAGGAGAGAATC

Downstream 100 bases:

>100_bases
ACCCGTCCCACCCGCTCGCGCTACCGCCCGCCGATCCCTACCCTCCGCCACCTTCGTCCCAGGAGAACTCCCATGACCCA
GCATCTTCCGACCGCTGTCC

Product: putative dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MITTATEIVLPGRVEPDGLLVTRRELPAPGPGQALVRVEASGVSFAEQQMRRGKYYDQPPFPFVPGYDLVGIVTAVGQDV
DAALVGRRVAALTKIGGWTSAALLDAADLVPVPEPLDAAAAETFVVNGITAWQMLFRTAKVRAGQTILVHGANGGVGSTL
VQLARAHGIHVIGTASARHRRAVEELGATWIDYRTDVARQVRELAPGGVNAVFDHIGGPGIVESFRLLAPHGTLVSYGTA
ATKDQEGNSRLPVLTLLARLVLWNALPNKRNAHFFNLWAGKRNLSRFRARIAADLGAVFDLAAQGVLRAQVAARVPLSAA
ARAVELAESGSVVGKVVLVADEG

Sequences:

>Translated_343_residues
MITTATEIVLPGRVEPDGLLVTRRELPAPGPGQALVRVEASGVSFAEQQMRRGKYYDQPPFPFVPGYDLVGIVTAVGQDV
DAALVGRRVAALTKIGGWTSAALLDAADLVPVPEPLDAAAAETFVVNGITAWQMLFRTAKVRAGQTILVHGANGGVGSTL
VQLARAHGIHVIGTASARHRRAVEELGATWIDYRTDVARQVRELAPGGVNAVFDHIGGPGIVESFRLLAPHGTLVSYGTA
ATKDQEGNSRLPVLTLLARLVLWNALPNKRNAHFFNLWAGKRNLSRFRARIAADLGAVFDLAAQGVLRAQVAARVPLSAA
ARAVELAESGSVVGKVVLVADEG
>Mature_343_residues
MITTATEIVLPGRVEPDGLLVTRRELPAPGPGQALVRVEASGVSFAEQQMRRGKYYDQPPFPFVPGYDLVGIVTAVGQDV
DAALVGRRVAALTKIGGWTSAALLDAADLVPVPEPLDAAAAETFVVNGITAWQMLFRTAKVRAGQTILVHGANGGVGSTL
VQLARAHGIHVIGTASARHRRAVEELGATWIDYRTDVARQVRELAPGGVNAVFDHIGGPGIVESFRLLAPHGTLVSYGTA
ATKDQEGNSRLPVLTLLARLVLWNALPNKRNAHFFNLWAGKRNLSRFRARIAADLGAVFDLAAQGVLRAQVAARVPLSAA
ARAVELAESGSVVGKVVLVADEG

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=318, Percent_Identity=32.0754716981132, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI24308257, Length=234, Percent_Identity=31.6239316239316, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI194239674, Length=225, Percent_Identity=30.2222222222222, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI13236495, Length=225, Percent_Identity=30.2222222222222, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI194239676, Length=151, Percent_Identity=38.4105960264901, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI22538446, Length=334, Percent_Identity=26.9461077844311, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI22538444, Length=334, Percent_Identity=26.9461077844311, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI67078404, Length=314, Percent_Identity=25.1592356687898, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI28557745, Length=332, Percent_Identity=28.0120481927711, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI67078406, Length=310, Percent_Identity=25.1612903225806, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=27.2445820433437, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=235, Percent_Identity=34.0425531914894, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536829, Length=231, Percent_Identity=28.1385281385281, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17556000, Length=241, Percent_Identity=27.8008298755187, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=225, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45550423, Length=320, Percent_Identity=30, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 36210; Mature: 36210

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTATEIVLPGRVEPDGLLVTRRELPAPGPGQALVRVEASGVSFAEQQMRRGKYYDQPP
CCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCC
FPFVPGYDLVGIVTAVGQDVDAALVGRRVAALTKIGGWTSAALLDAADLVPVPEPLDAAA
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
AETFVVNGITAWQMLFRTAKVRAGQTILVHGANGGVGSTLVQLARAHGIHVIGTASARHR
HHHHEECCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEECCCHHHH
RAVEELGATWIDYRTDVARQVRELAPGGVNAVFDHIGGPGIVESFRLLAPHGTLVSYGTA
HHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCCEEECCCC
ATKDQEGNSRLPVLTLLARLVLWNALPNKRNAHFFNLWAGKRNLSRFRARIAADLGAVFD
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
LAAQGVLRAQVAARVPLSAAARAVELAESGSVVGKVVLVADEG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEECCC
>Mature Secondary Structure
MITTATEIVLPGRVEPDGLLVTRRELPAPGPGQALVRVEASGVSFAEQQMRRGKYYDQPP
CCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCC
FPFVPGYDLVGIVTAVGQDVDAALVGRRVAALTKIGGWTSAALLDAADLVPVPEPLDAAA
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
AETFVVNGITAWQMLFRTAKVRAGQTILVHGANGGVGSTLVQLARAHGIHVIGTASARHR
HHHHEECCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEECCCHHHH
RAVEELGATWIDYRTDVARQVRELAPGGVNAVFDHIGGPGIVESFRLLAPHGTLVSYGTA
HHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCCEEECCCC
ATKDQEGNSRLPVLTLLARLVLWNALPNKRNAHFFNLWAGKRNLSRFRARIAADLGAVFD
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
LAAQGVLRAQVAARVPLSAAARAVELAESGSVVGKVVLVADEG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]