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The map label for this gene is cobF [H]

Identifier: 54026995

GI number: 54026995

Start: 5235798

End: 5236562

Strand: Reverse

Name: cobF [H]

Synonym: nfa50210

Alternate gene names: 54026995

Gene position: 5236562-5235798 (Counterclockwise)

Preceding gene: 54027003

Following gene: 54026994

Centisome position: 86.97

GC content: 71.24

Gene sequence:

>765_bases
ATGCGCAAGCTCTACGTGATCGGCATCGGCGCCGGCGACCCCGGCCAGGTGACGATGCAGGCCGTCGCGGCCATGCGGCA
GGTCGAGGTGTTCTTCGTGATCGGCAAGGGCGAGCAGAAGCGCGAGCTGGCCGAGCTGCGGACCGCGATCCTGCACGCGC
ACGTGGACCGGCCCTACCGGGTGGTGCCGATCCCGGATCCGCCGCGCGATCGCACACCGGACGACTATCGCGGGGTGGTC
GAGGACTGGCACGAGCGGCGCTCGCTGCTGCTGGAACAGGCGTTCGCGGAAACCGGCGGGGTGGGCGGCATCCTGGTCTG
GGGCGACCCGTCCCTCTACGACAGCACCCTGCGCATGGTCGAGCGGGTGCTCGCGCGCGGCGCGATGCGCTTCGACTACG
AGGTGATCCCCGGCATCACCAGCGCGCAGGCGCTGGCGGCCCGGCATCGCATCGTGCTGCACGACATCGGCGAGCCGGTG
CACATCACCACCGGCCGCAAGCTGCGCGAGGAAGGTCTCGGGCCGGGCTCGACGCTGGTGATGCTCGACGGGGAGTGCTC
GTTCACCACCGTCGCCGAGCCGGACGTGCACATCTGGTGGGGCGCCTATCTCGGCATGCCGGACGAGACGTTGATCGCGG
GGCCGCTGCGCGAGGTGGGGGAGCGCATCGCCGCGGTCCGGGCGCGGCTGCGGGACCGCAAGGGCTGGATCATGGACATC
TACCTGCTGCGTCGTAGCCCGGGGAATGTCGGTGCGGCCGGGTAG

Upstream 100 bases:

>100_bases
GAGCCGCAGGAGGTCCTCGTATTGCCTGTCCGTCGCCACGCCTGGCAGCTTAGTCGGGCCGCGCCCGGCGCCCGCCGGTG
ATCCTGGCATGCTCGGGCGA

Downstream 100 bases:

>100_bases
CCTGGCGATGTGCCCGAGCTACCCGAAGTGGAGGCGCTGGCCCAGTTCCTGCGCGAACACGCCGTCGGCGCGGTGGTGGG
GCGAGTCGATGTGGCCGCGC

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRKLYVIGIGAGDPGQVTMQAVAAMRQVEVFFVIGKGEQKRELAELRTAILHAHVDRPYRVVPIPDPPRDRTPDDYRGVV
EDWHERRSLLLEQAFAETGGVGGILVWGDPSLYDSTLRMVERVLARGAMRFDYEVIPGITSAQALAARHRIVLHDIGEPV
HITTGRKLREEGLGPGSTLVMLDGECSFTTVAEPDVHIWWGAYLGMPDETLIAGPLREVGERIAAVRARLRDRKGWIMDI
YLLRRSPGNVGAAG

Sequences:

>Translated_254_residues
MRKLYVIGIGAGDPGQVTMQAVAAMRQVEVFFVIGKGEQKRELAELRTAILHAHVDRPYRVVPIPDPPRDRTPDDYRGVV
EDWHERRSLLLEQAFAETGGVGGILVWGDPSLYDSTLRMVERVLARGAMRFDYEVIPGITSAQALAARHRIVLHDIGEPV
HITTGRKLREEGLGPGSTLVMLDGECSFTTVAEPDVHIWWGAYLGMPDETLIAGPLREVGERIAAVRARLRDRKGWIMDI
YLLRRSPGNVGAAG
>Mature_254_residues
MRKLYVIGIGAGDPGQVTMQAVAAMRQVEVFFVIGKGEQKRELAELRTAILHAHVDRPYRVVPIPDPPRDRTPDDYRGVV
EDWHERRSLLLEQAFAETGGVGGILVWGDPSLYDSTLRMVERVLARGAMRFDYEVIPGITSAQALAARHRIVLHDIGEPV
HITTGRKLREEGLGPGSTLVMLDGECSFTTVAEPDVHIWWGAYLGMPDETLIAGPLREVGERIAAVRARLRDRKGWIMDI
YLLRRSPGNVGAAG

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28151; Mature: 28151

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLYVIGIGAGDPGQVTMQAVAAMRQVEVFFVIGKGEQKRELAELRTAILHAHVDRPYR
CCEEEEEEECCCCCCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEE
VVPIPDPPRDRTPDDYRGVVEDWHERRSLLLEQAFAETGGVGGILVWGDPSLYDSTLRMV
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
ERVLARGAMRFDYEVIPGITSAQALAARHRIVLHDIGEPVHITTGRKLREEGLGPGSTLV
HHHHHCCCCCCCEEECCCCCHHHHHHHHCEEEEEECCCCEEEECCCHHHHHCCCCCCEEE
MLDGECSFTTVAEPDVHIWWGAYLGMPDETLIAGPLREVGERIAAVRARLRDRKGWIMDI
EECCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
YLLRRSPGNVGAAG
EEEECCCCCCCCCC
>Mature Secondary Structure
MRKLYVIGIGAGDPGQVTMQAVAAMRQVEVFFVIGKGEQKRELAELRTAILHAHVDRPYR
CCEEEEEEECCCCCCHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEE
VVPIPDPPRDRTPDDYRGVVEDWHERRSLLLEQAFAETGGVGGILVWGDPSLYDSTLRMV
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
ERVLARGAMRFDYEVIPGITSAQALAARHRIVLHDIGEPVHITTGRKLREEGLGPGSTLV
HHHHHCCCCCCCEEECCCCCHHHHHHHHCEEEEEECCCCEEEECCCHHHHHCCCCCCEEE
MLDGECSFTTVAEPDVHIWWGAYLGMPDETLIAGPLREVGERIAAVRARLRDRKGWIMDI
EECCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
YLLRRSPGNVGAAG
EEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]