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The map label for this gene is sucC

Identifier: 54026965

GI number: 54026965

Start: 5206121

End: 5207287

Strand: Reverse

Name: sucC

Synonym: nfa49910

Alternate gene names: 54026965

Gene position: 5207287-5206121 (Counterclockwise)

Preceding gene: 54026968

Following gene: 54026964

Centisome position: 86.48

GC content: 67.44

Gene sequence:

>1167_bases
ATGGATCTCTTCGAATATCAGGCGAAGGAGCTCTTCGTTAAGCACGGAGTGCCTTCGTCCGAGGGCCGCGTCACGGACAC
GGCCGAGGACGCCCGCGCGATCGCGGCGGAAATCGGCAAGCCGGTGATGATCAAGTCCCAGGTCAAGGTCGGTGGCCGCG
GTAAGGCCGGTGGCGTGAAGTACGCCGCGACGCCGGAGGACGCGTTCACCCACGCGCAGAACATCCTCGGCCTGGACATC
AAGGGACACATCACCAAGAAGATCCTGGTCGCCGAGGCGAAGGACATCGCCGAGGAGTACTACATCTCCTTCCTGCTCGA
CCGCGCCAACCGCACCTACCTGGCCATGTGCTCGGTCGAGGGCGGCATGGAGATCGAGGAGGTCGCCGCGACCAAGCCCG
AGCGCCTGGCCAAGGTGCCCGTCGACGCCGTCAAGGGCGTCGATCTGGCCTTCGCCCGCTCGATCGCCGAGCAGGGCCAC
CTGCCCGCCGAGGTGCTCGACGCCGCGGCCGTGACCATCCAGAAGCTGTGGGAGGTCTTCGTCGCCGAGGACGCGACCCT
GGTGGAGGTCAACCCGCTGGTGCGCACCCCCCAGGACGAGATCCTCGCCCTCGACGGCAAGGTGACCCTGGACGAGAACG
CCGGCTTCCGGCACCCCGAGCACGACGAGTTCGCGGACGTCGACGCCACCGACCCGCTCGAGCTCAAGGCCAAGGAGAAC
GACCTCAACTACGTCAAGCTCGACGGCGAGGTCGGCATCATCGGCAACGGCGCCGGCCTGGTCATGTCGACCCTGGACGT
GGTCGCCTACGCCGGTGAGAACCACGGCGGCGTGAAGCCGGCCAACTTCCTCGACATCGGTGGCGGCGCCTCGGCCGAGG
TGATGGCGGCCGGGCTCGACGTCATCCTCAACGACGCGCAGGTCAAGAGCGTGTTCGTGAACGTGTTCGGTGGCATCACC
GCGTGTGACGCGGTCGCCAACGGCATCGTCAAGGCGCTCGAGATCCTGGGCGACGAGGCGAACAAGCCGCTGGTCGTGCG
GCTGGACGGCAACAAGGTCGACGAGGGCCGCAAGATCCTCGTCGAGGCCGCGCACCCGCTGGTGACGCTGGCGCAGACAA
TGGACGAAGGCGCCGACAAGGCCGCCGAACTGGCAGCCGCCCGCTAA

Upstream 100 bases:

>100_bases
GGCCCTCCATGTGACTGGTTAGAGTCCGACCCGACCCGCTTCCGACGTCGGGCCGCCAACAAAGACGTTGTCATAGCAAC
GCAGACGAGACGGTGAGTAC

Downstream 100 bases:

>100_bases
CGACGGCCGAGCAAGGGACCACACGACATGTCAATCTTCCTGAACAAGGACTCCAAGGTCATCGTCCAGGGCATCACCGG
CGGTGAAGGCACCAAGCACA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MDLFEYQAKELFVKHGVPSSEGRVTDTAEDARAIAAEIGKPVMIKSQVKVGGRGKAGGVKYAATPEDAFTHAQNILGLDI
KGHITKKILVAEAKDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVDAVKGVDLAFARSIAEQGH
LPAEVLDAAAVTIQKLWEVFVAEDATLVEVNPLVRTPQDEILALDGKVTLDENAGFRHPEHDEFADVDATDPLELKAKEN
DLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAEVMAAGLDVILNDAQVKSVFVNVFGGIT
ACDAVANGIVKALEILGDEANKPLVVRLDGNKVDEGRKILVEAAHPLVTLAQTMDEGADKAAELAAAR

Sequences:

>Translated_388_residues
MDLFEYQAKELFVKHGVPSSEGRVTDTAEDARAIAAEIGKPVMIKSQVKVGGRGKAGGVKYAATPEDAFTHAQNILGLDI
KGHITKKILVAEAKDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVDAVKGVDLAFARSIAEQGH
LPAEVLDAAAVTIQKLWEVFVAEDATLVEVNPLVRTPQDEILALDGKVTLDENAGFRHPEHDEFADVDATDPLELKAKEN
DLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAEVMAAGLDVILNDAQVKSVFVNVFGGIT
ACDAVANGIVKALEILGDEANKPLVVRLDGNKVDEGRKILVEAAHPLVTLAQTMDEGADKAAELAAAR
>Mature_388_residues
MDLFEYQAKELFVKHGVPSSEGRVTDTAEDARAIAAEIGKPVMIKSQVKVGGRGKAGGVKYAATPEDAFTHAQNILGLDI
KGHITKKILVAEAKDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVDAVKGVDLAFARSIAEQGH
LPAEVLDAAAVTIQKLWEVFVAEDATLVEVNPLVRTPQDEILALDGKVTLDENAGFRHPEHDEFADVDATDPLELKAKEN
DLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAEVMAAGLDVILNDAQVKSVFVNVFGGIT
ACDAVANGIVKALEILGDEANKPLVVRLDGNKVDEGRKILVEAAHPLVTLAQTMDEGADKAAELAAAR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=400, Percent_Identity=35, Blast_Score=242, Evalue=3e-64,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=36.71875, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=36.986301369863, Blast_Score=220, Evalue=2e-57,
Organism=Escherichia coli, GI1786948, Length=376, Percent_Identity=41.4893617021277, Blast_Score=261, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=33.9195979899498, Blast_Score=230, Evalue=9e-61,
Organism=Caenorhabditis elegans, GI17567829, Length=399, Percent_Identity=34.5864661654135, Blast_Score=223, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321683, Length=402, Percent_Identity=35.3233830845771, Blast_Score=237, Evalue=2e-63,
Organism=Drosophila melanogaster, GI21356231, Length=399, Percent_Identity=35.8395989974937, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI161078106, Length=402, Percent_Identity=35.3233830845771, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24645208, Length=402, Percent_Identity=35.3233830845771, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI281361397, Length=403, Percent_Identity=35.2357320099256, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI281361395, Length=403, Percent_Identity=35.2357320099256, Blast_Score=215, Evalue=5e-56,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_NOCFA (Q5YPP8)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_121207.1
- HSSP:   P0A836
- ProteinModelPortal:   Q5YPP8
- SMR:   Q5YPP8
- GeneID:   3111579
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa49910
- NMPDR:   fig|247156.1.peg.4798
- HOGENOM:   HBG315432
- OMA:   IFINILG
- ProtClustDB:   PRK00696
- BioCyc:   NFAR247156:NFA49910-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41072; Mature: 41072

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFEYQAKELFVKHGVPSSEGRVTDTAEDARAIAAEIGKPVMIKSQVKVGGRGKAGGVK
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATPEDAFTHAQNILGLDIKGHITKKILVAEAKDIAEEYYISFLLDRANRTYLAMCSVE
EECCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGMEIEEVAATKPERLAKVPVDAVKGVDLAFARSIAEQGHLPAEVLDAAAVTIQKLWEVF
CCCCHHHHHCCCHHHHHCCCHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VAEDATLVEVNPLVRTPQDEILALDGKVTLDENAGFRHPEHDEFADVDATDPLELKAKEN
HCCCCEEEEECCCCCCCCHHEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
DLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAEVMAAGLD
CCCEEEECCEEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCCHHHHHHCHH
VILNDAQVKSVFVNVFGGITACDAVANGIVKALEILGDEANKPLVVRLDGNKVDEGRKIL
HEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEE
VEAAHPLVTLAQTMDEGADKAAELAAAR
EEHHCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLFEYQAKELFVKHGVPSSEGRVTDTAEDARAIAAEIGKPVMIKSQVKVGGRGKAGGVK
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATPEDAFTHAQNILGLDIKGHITKKILVAEAKDIAEEYYISFLLDRANRTYLAMCSVE
EECCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGMEIEEVAATKPERLAKVPVDAVKGVDLAFARSIAEQGHLPAEVLDAAAVTIQKLWEVF
CCCCHHHHHCCCHHHHHCCCHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VAEDATLVEVNPLVRTPQDEILALDGKVTLDENAGFRHPEHDEFADVDATDPLELKAKEN
HCCCCEEEEECCCCCCCCHHEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
DLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAEVMAAGLD
CCCEEEECCEEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCCHHHHHHCHH
VILNDAQVKSVFVNVFGGITACDAVANGIVKALEILGDEANKPLVVRLDGNKVDEGRKIL
HEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEE
VEAAHPLVTLAQTMDEGADKAAELAAAR
EEHHCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA