Click here to switch to the map view.

The map label for this gene is sbcD [H]

Identifier: 54026767

GI number: 54026767

Start: 5005080

End: 5006264

Strand: Reverse

Name: sbcD [H]

Synonym: nfa47930

Alternate gene names: 54026767

Gene position: 5006264-5005080 (Counterclockwise)

Preceding gene: 54026769

Following gene: 54026766

Centisome position: 83.14

GC content: 69.79

Gene sequence:

>1185_bases
ATGCGGCTGCTGCACACCTCGGATTGGCATGTGGGCCGGACGTTTCACGGCGTCGATCTGCTCGTCGATCAGGCGCGCTC
GCTGGCGGCGATCGCGGAGCTGGTGGCCGAGGAGTCGGTGGACGTGGTGGTGGTGCCGGGTGACGTCTACGACCGCTCGA
TTCCCAGCGCGGACGCGATCGCGGTGTGCACCAGGGGTTTGGAGGCGATCAGGGCCGCGGGTGCGGTGATCGTGGCGACG
TCGGGCAATCATGATTCGCCTGCTCGGCTCGGGGCGGGGGCGAGTTTCGCGGCGGCGGGCGGGTTGTATCTGCGGACGCG
GTTGGCGGAGGCGGACCGGCCGATCGTGTTGCGTGACGATGCGGGTGAGGTGGCCTTCTACGGCATTCCGTATCTGGAGC
CGGAGGTGGTGCGCGGGGAGTTGGGTGTGCCGCGGGCACGCTCGCACGCCGAGGTGCTGGATGTGGTGATGGATCGGGTG
CGGGCGGATCTGGCGGGCAGGCCGGGGGTGCGGTCGGTGGTGCTCGCGCACGCGTTCGTGGTCGGTGGGGCGGCGACGGG
GTCGGAGCGCTCGATTTCGGTGGGCGGCGTGGAGACGGTGCCGTTGTCGGCGTTCGACGGTGTCGATTACGTGGCGCTCG
GGCATCTGCATTCGCCGCAGACGTTGTCGGCGTCGGTGCGGTATTCGGGTTCGCCGCTGCCGTATTCGTTCGGGGAGGCG
TCGCACCGCAAGGCGGTGTGGATCATTGATCTGGACGAGTCGGGGGTGGCCGAGGTGCGGCGTCGGGATCTGCCGGTGGT
GCGGGGTTTGAGCCGGTTGACCGGCACGCTCGAGGAGTTGCTGTCCGATCCGGCGCACGAGGACGCGGTGGCGCATTACG
TGTCGGCGACGTTGACCGATACGGCGCGCCCGATCGACGCGATGCGCCGGCTGCGGAACCGGTTCCCGCATGCGGTCCAC
GTGGAATGGGTTCGGCCGGACGCCGATTCGGTGCTGCATTATCGGGAGCGGGTGCGCGGGCGCGATGACGCGGAGGTCGC
GCGCAGTTTTCTCACCGATGTGCGGGGTGAGCCGTCGACGGCGGAATTGCGGTGGCTGGAGCGGGCGTTGGCCGCGGGTG
TCACCGAGCCGGAGGGTGCCGCGGTGCTCGCCGGATCGGATGCGGCCGAGGAATTGTCGGCGTGA

Upstream 100 bases:

>100_bases
GGGTCGCGACGAAGGAGCGGCAAGAAGACACAGCCGCGACCCGCCCGACGAAGGAGGGCAAATCGAACCCTGTCGGTGGG
AGGGCTTACGGTGTCGAACC

Downstream 100 bases:

>100_bases
GGGAGTCGGGGGTGGGTGAGGTGGCCGGATGAGGCTGCATCGGCTGGAGATGACGGCGTTCGGCCCGTTCGCGCAGCCGA
CGGTGGTCGATTTCGACGCG

Product: putative ATP-dependent dsDNA exonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRLLHTSDWHVGRTFHGVDLLVDQARSLAAIAELVAEESVDVVVVPGDVYDRSIPSADAIAVCTRGLEAIRAAGAVIVAT
SGNHDSPARLGAGASFAAAGGLYLRTRLAEADRPIVLRDDAGEVAFYGIPYLEPEVVRGELGVPRARSHAEVLDVVMDRV
RADLAGRPGVRSVVLAHAFVVGGAATGSERSISVGGVETVPLSAFDGVDYVALGHLHSPQTLSASVRYSGSPLPYSFGEA
SHRKAVWIIDLDESGVAEVRRRDLPVVRGLSRLTGTLEELLSDPAHEDAVAHYVSATLTDTARPIDAMRRLRNRFPHAVH
VEWVRPDADSVLHYRERVRGRDDAEVARSFLTDVRGEPSTAELRWLERALAAGVTEPEGAAVLAGSDAAEELSA

Sequences:

>Translated_394_residues
MRLLHTSDWHVGRTFHGVDLLVDQARSLAAIAELVAEESVDVVVVPGDVYDRSIPSADAIAVCTRGLEAIRAAGAVIVAT
SGNHDSPARLGAGASFAAAGGLYLRTRLAEADRPIVLRDDAGEVAFYGIPYLEPEVVRGELGVPRARSHAEVLDVVMDRV
RADLAGRPGVRSVVLAHAFVVGGAATGSERSISVGGVETVPLSAFDGVDYVALGHLHSPQTLSASVRYSGSPLPYSFGEA
SHRKAVWIIDLDESGVAEVRRRDLPVVRGLSRLTGTLEELLSDPAHEDAVAHYVSATLTDTARPIDAMRRLRNRFPHAVH
VEWVRPDADSVLHYRERVRGRDDAEVARSFLTDVRGEPSTAELRWLERALAAGVTEPEGAAVLAGSDAAEELSA
>Mature_394_residues
MRLLHTSDWHVGRTFHGVDLLVDQARSLAAIAELVAEESVDVVVVPGDVYDRSIPSADAIAVCTRGLEAIRAAGAVIVAT
SGNHDSPARLGAGASFAAAGGLYLRTRLAEADRPIVLRDDAGEVAFYGIPYLEPEVVRGELGVPRARSHAEVLDVVMDRV
RADLAGRPGVRSVVLAHAFVVGGAATGSERSISVGGVETVPLSAFDGVDYVALGHLHSPQTLSASVRYSGSPLPYSFGEA
SHRKAVWIIDLDESGVAEVRRRDLPVVRGLSRLTGTLEELLSDPAHEDAVAHYVSATLTDTARPIDAMRRLRNRFPHAVH
VEWVRPDADSVLHYRERVRGRDDAEVARSFLTDVRGEPSTAELRWLERALAAGVTEPEGAAVLAGSDAAEELSA

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

Organism=Escherichia coli, GI1786598, Length=286, Percent_Identity=27.6223776223776, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 42051; Mature: 42051

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLHTSDWHVGRTFHGVDLLVDQARSLAAIAELVAEESVDVVVVPGDVYDRSIPSADAI
CCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCHHHH
AVCTRGLEAIRAAGAVIVATSGNHDSPARLGAGASFAAAGGLYLRTRLAEADRPIVLRDD
HHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCCCCHHHCCCHHHHHHHHCCCCCEEEECC
AGEVAFYGIPYLEPEVVRGELGVPRARSHAEVLDVVMDRVRADLAGRPGVRSVVLAHAFV
CCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VGGAATGSERSISVGGVETVPLSAFDGVDYVALGHLHSPQTLSASVRYSGSPLPYSFGEA
HCCCCCCCCCEEEECCCEECCCHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCC
SHRKAVWIIDLDESGVAEVRRRDLPVVRGLSRLTGTLEELLSDPAHEDAVAHYVSATLTD
CCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TARPIDAMRRLRNRFPHAVHVEWVRPDADSVLHYRERVRGRDDAEVARSFLTDVRGEPST
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCH
AELRWLERALAAGVTEPEGAAVLAGSDAAEELSA
HHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCC
>Mature Secondary Structure
MRLLHTSDWHVGRTFHGVDLLVDQARSLAAIAELVAEESVDVVVVPGDVYDRSIPSADAI
CCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHCCCCCHHHH
AVCTRGLEAIRAAGAVIVATSGNHDSPARLGAGASFAAAGGLYLRTRLAEADRPIVLRDD
HHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCCCCHHHCCCHHHHHHHHCCCCCEEEECC
AGEVAFYGIPYLEPEVVRGELGVPRARSHAEVLDVVMDRVRADLAGRPGVRSVVLAHAFV
CCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VGGAATGSERSISVGGVETVPLSAFDGVDYVALGHLHSPQTLSASVRYSGSPLPYSFGEA
HCCCCCCCCCEEEECCCEECCCHHCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCC
SHRKAVWIIDLDESGVAEVRRRDLPVVRGLSRLTGTLEELLSDPAHEDAVAHYVSATLTD
CCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TARPIDAMRRLRNRFPHAVHVEWVRPDADSVLHYRERVRGRDDAEVARSFLTDVRGEPST
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCH
AELRWLERALAAGVTEPEGAAVLAGSDAAEELSA
HHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA