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The map label for this gene is fadE40 [H]

Identifier: 54026648

GI number: 54026648

Start: 4876060

End: 4877232

Strand: Reverse

Name: fadE40 [H]

Synonym: nfa46750

Alternate gene names: 54026648

Gene position: 4877232-4876060 (Counterclockwise)

Preceding gene: 54026654

Following gene: 54026647

Centisome position: 81.0

GC content: 66.67

Gene sequence:

>1173_bases
ATGAAAATATCCCTGTCCCCTGACGAGGTGGCCTTCCGCGACGAATTGCGGCAGTTCTACCGCACCCAGATCCCCGCCGA
GATCCGTGAGCGCGTCAAGCACGGCAAGGAACTGTCCCGCGAGGACATCGTGACCGCGCACAAGATCCTCAACGACCACG
GGCTGGCCGTGCCGAACTGGCCGGTCGAGTGGGGCGGCAAGGACTGGACCCCCATGCAGCGCCACATCTGGCAGGACGAG
ATGCAGCTCGCCTCGGTGCCCGAGCCGCTGACGTTCAACGCCCAGATGGTCGGCCCGGTGATCGCGCACTTCGGCTCGCA
GGAGCTCAAGGAGCGTTTCCTGCCGCCGACCGCGGCCCTCGACATCTGGTGGTGCCAGGGCTTCTCCGAGCCCGACGCGG
GCTCCGATCTGGCCTCGCTGCGCACCACCGCCGTGCGCGACGGCGACTCCTACATCGTCAACGGCCAGAAGATCTGGACC
ACCCTGGCCCAGCACGCCGACTGGATCTTCTGCCTGGTGCGCACCGATCCGAACGCGCCCAAGAAGCAGGCGGGCATCTC
CTTCCTGCTCTTCGACGTCAAGAGCCCCGGCGTGACCATCCGCCCGATCAAGCTGATCGACGGCGGTTACGAGGTCAACG
AGGTGTTCTTCGAGAACGTCCGGGTGCCCGCCGACCAGCTCGTCGGTGAGGAGAACATGGGCTGGACCTACGCGAAGTTC
CTGCTCGGCAACGAGCGCACCGGCATCACCGGCGTGGGCCGCACCAAGGTCAAGATCGGCGTGGCCAAGGAGTACGCGCG
CCAGGTGAAGTCCGGTTCCGGCACGCTGCTCGAGGATCCGGTCTTCGCGGCCAGGATCGCCGAACTGGAGAACGAACTGA
TCGCGCTGGAGCTGACCCAGTTGCGCGTGGTCTCCAACTCCTCGGACGGCAAGCCCAACCCGGCCTCCTCGGTGCTCAAA
CTGCGCGGTTCGGAACTACAGCAGGCCGCCACCGAGCTGTTGCTCGACATCGCGGGGGCCGACGCGATCCCGGTCGGCGC
CGAGGGCATCGCCTCGCCCGGCTGGGCGCAGCGCAGCGGCCCCGGCTACCTCAACTACCGCAAGACCACCATCTACGGAG
GCTCGAACGAGGTGCAGCGCACCATCATCGCCTCCACGATCCTCGGATTGTGA

Upstream 100 bases:

>100_bases
TCTTGCCCCATCGGGTACACGTGATGTGATCCACTCGACAGTGCCGGATTACCGAGGGGTAGGTTCTACTCGGACGTACG
AGACACAACGGGAGCTGCGT

Downstream 100 bases:

>100_bases
GGCCAGGTCATGGATTTCGATCTCACCGATGAACAGGTCATGCTGCGCGACACCGTGCGCGATCTGCTGGCCCGCACCTA
CGACCCGGAGACCCGGCTGA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKISLSPDEVAFRDELRQFYRTQIPAEIRERVKHGKELSREDIVTAHKILNDHGLAVPNWPVEWGGKDWTPMQRHIWQDE
MQLASVPEPLTFNAQMVGPVIAHFGSQELKERFLPPTAALDIWWCQGFSEPDAGSDLASLRTTAVRDGDSYIVNGQKIWT
TLAQHADWIFCLVRTDPNAPKKQAGISFLLFDVKSPGVTIRPIKLIDGGYEVNEVFFENVRVPADQLVGEENMGWTYAKF
LLGNERTGITGVGRTKVKIGVAKEYARQVKSGSGTLLEDPVFAARIAELENELIALELTQLRVVSNSSDGKPNPASSVLK
LRGSELQQAATELLLDIAGADAIPVGAEGIASPGWAQRSGPGYLNYRKTTIYGGSNEVQRTIIASTILGL

Sequences:

>Translated_390_residues
MKISLSPDEVAFRDELRQFYRTQIPAEIRERVKHGKELSREDIVTAHKILNDHGLAVPNWPVEWGGKDWTPMQRHIWQDE
MQLASVPEPLTFNAQMVGPVIAHFGSQELKERFLPPTAALDIWWCQGFSEPDAGSDLASLRTTAVRDGDSYIVNGQKIWT
TLAQHADWIFCLVRTDPNAPKKQAGISFLLFDVKSPGVTIRPIKLIDGGYEVNEVFFENVRVPADQLVGEENMGWTYAKF
LLGNERTGITGVGRTKVKIGVAKEYARQVKSGSGTLLEDPVFAARIAELENELIALELTQLRVVSNSSDGKPNPASSVLK
LRGSELQQAATELLLDIAGADAIPVGAEGIASPGWAQRSGPGYLNYRKTTIYGGSNEVQRTIIASTILGL
>Mature_390_residues
MKISLSPDEVAFRDELRQFYRTQIPAEIRERVKHGKELSREDIVTAHKILNDHGLAVPNWPVEWGGKDWTPMQRHIWQDE
MQLASVPEPLTFNAQMVGPVIAHFGSQELKERFLPPTAALDIWWCQGFSEPDAGSDLASLRTTAVRDGDSYIVNGQKIWT
TLAQHADWIFCLVRTDPNAPKKQAGISFLLFDVKSPGVTIRPIKLIDGGYEVNEVFFENVRVPADQLVGEENMGWTYAKF
LLGNERTGITGVGRTKVKIGVAKEYARQVKSGSGTLLEDPVFAARIAELENELIALELTQLRVVSNSSDGKPNPASSVLK
LRGSELQQAATELLLDIAGADAIPVGAEGIASPGWAQRSGPGYLNYRKTTIYGGSNEVQRTIIASTILGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=391, Percent_Identity=26.5984654731458, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557233, Length=349, Percent_Identity=29.2263610315186, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4557231, Length=385, Percent_Identity=23.3766233766234, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI187960098, Length=385, Percent_Identity=23.3766233766234, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226958412, Length=234, Percent_Identity=26.0683760683761, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI226958414, Length=191, Percent_Identity=28.7958115183246, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501859, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI7656849, Length=307, Percent_Identity=24.7557003257329, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4557235, Length=222, Percent_Identity=30.6306306306306, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI76496475, Length=222, Percent_Identity=30.6306306306306, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38505218, Length=230, Percent_Identity=30, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI87081958, Length=274, Percent_Identity=26.2773722627737, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=348, Percent_Identity=31.8965517241379, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17505929, Length=344, Percent_Identity=30.8139534883721, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=402, Percent_Identity=28.1094527363184, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=27.3972602739726, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=401, Percent_Identity=25.1870324189526, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=305, Percent_Identity=27.8688524590164, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=251, Percent_Identity=29.4820717131474, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=250, Percent_Identity=28.4, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=332, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=202, Percent_Identity=28.7128712871287, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=194, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=156, Percent_Identity=32.6923076923077, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=300, Percent_Identity=27.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=155, Percent_Identity=32.9032258064516, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356377, Length=395, Percent_Identity=24.0506329113924, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21355753, Length=253, Percent_Identity=26.8774703557312, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19920834, Length=399, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281363737, Length=172, Percent_Identity=32.5581395348837, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666513, Length=350, Percent_Identity=24.5714285714286, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646207, Length=384, Percent_Identity=25, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24660351, Length=283, Percent_Identity=27.5618374558304, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42988; Mature: 42988

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISLSPDEVAFRDELRQFYRTQIPAEIRERVKHGKELSREDIVTAHKILNDHGLAVPNW
CEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
PVEWGGKDWTPMQRHIWQDEMQLASVPEPLTFNAQMVGPVIAHFGSQELKERFLPPTAAL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCHHHHHHHCCCCCHHE
DIWWCQGFSEPDAGSDLASLRTTAVRDGDSYIVNGQKIWTTLAQHADWIFCLVRTDPNAP
EEHEECCCCCCCCCCHHHHHHHHHEECCCCEEECCHHHHHHHHHCCCEEEEEEECCCCCC
KKQAGISFLLFDVKSPGVTIRPIKLIDGGYEVNEVFFENVRVPADQLVGEENMGWTYAKF
HHHCCCEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCEEEHH
LLGNERTGITGVGRTKVKIGVAKEYARQVKSGSGTLLEDPVFAARIAELENELIALELTQ
EECCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHCCEEEEEEEE
LRVVSNSSDGKPNPASSVLKLRGSELQQAATELLLDIAGADAIPVGAEGIASPGWAQRSG
EEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PGYLNYRKTTIYGGSNEVQRTIIASTILGL
CCCEEEEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKISLSPDEVAFRDELRQFYRTQIPAEIRERVKHGKELSREDIVTAHKILNDHGLAVPNW
CEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
PVEWGGKDWTPMQRHIWQDEMQLASVPEPLTFNAQMVGPVIAHFGSQELKERFLPPTAAL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCHHHHHHHCCCCCHHE
DIWWCQGFSEPDAGSDLASLRTTAVRDGDSYIVNGQKIWTTLAQHADWIFCLVRTDPNAP
EEHEECCCCCCCCCCHHHHHHHHHEECCCCEEECCHHHHHHHHHCCCEEEEEEECCCCCC
KKQAGISFLLFDVKSPGVTIRPIKLIDGGYEVNEVFFENVRVPADQLVGEENMGWTYAKF
HHHCCCEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCEEEHH
LLGNERTGITGVGRTKVKIGVAKEYARQVKSGSGTLLEDPVFAARIAELENELIALELTQ
EECCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHCCEEEEEEEE
LRVVSNSSDGKPNPASSVLKLRGSELQQAATELLLDIAGADAIPVGAEGIASPGWAQRSG
EEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PGYLNYRKTTIYGGSNEVQRTIIASTILGL
CCCEEEEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]