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The map label for this gene is gntR [H]

Identifier: 54026443

GI number: 54026443

Start: 4636917

End: 4637624

Strand: Reverse

Name: gntR [H]

Synonym: nfa44700

Alternate gene names: 54026443

Gene position: 4637624-4636917 (Counterclockwise)

Preceding gene: 54026447

Following gene: 54026441

Centisome position: 77.02

GC content: 75.14

Gene sequence:

>708_bases
ATGGGATACCAAAGCGGTGGTGCGGGTGCGAGGATGGGCCGCATGGGGTTCGAGTCGGAGTCCGACCGGGTGACGCGGCA
GTTGCGCGACCAGATCGTCGGGGGCGTGCGCGCGCCGGGAAGCAGGCTGGTCGAGCGCGAGCTGGCCGCCGAGCTGGGCG
TGAGCCGGTTGCCGGTACGCGAAGCGCTGCGCGTGCTGGTCGCCGAAGGACTGGTGACGGCGCGGCCGCGGAGCTGGGCG
GTGGTGCGCGAATTCACCCCGGCCGATGTCGCCGACCTGCTCGAGGTGCGCTCCGCCGTCGACGTGCTGGCCTTCCGGTT
GGCCGCGCAGCGGGCGACCCGCGCCGGACTCGCCGAACTGCGCGCCGTGCTCGACGAGGAACAGGCGGCCGCCCGCGCCG
GCGACGCCCCGCGCGCCCGCCGCGCCGCCGCCGATTTCCACGAGACCGTCACCCGGCTGGCCGGCAACGACCTGCTGCTC
GAACTCGAGGCGACATTGCGCAGCCGGATGCGCTGGCTGCTCGGCAGACACGACGACCTCGGCCTGGTCGCCGACGAACA
CGAGCGGCTGTATGCGGCGATCGCCGCCCGGGACTCCGCGCGCGCCGAGGCACTGGCGGTGGCGCACATCGAGACCAGCC
GCGCCTTGGCCGCGCGCCGGGCGGACACGCGAGCGACCGGCCGGACCGAGCGGGACCGTCCGGCCTGA

Upstream 100 bases:

>100_bases
CGCACGGTTTCAGGCTAGGACCGCGGCGCGCCGGTGGACAACGTCACCGCGCGGGGGCGCCTGGTTCCCGACCACATCGC
CGGCGGCGAGGCCGACAGCG

Downstream 100 bases:

>100_bases
GACCCCGCTACCCGGCGAGGCGCGCGGCCAGCTCCGCGTGCAGGGCCCGCATCTCCTCCTCGAACAGCGGATCCGGTCCC
GCGACCGGCACACCCGGCGC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MGYQSGGAGARMGRMGFESESDRVTRQLRDQIVGGVRAPGSRLVERELAAELGVSRLPVREALRVLVAEGLVTARPRSWA
VVREFTPADVADLLEVRSAVDVLAFRLAAQRATRAGLAELRAVLDEEQAAARAGDAPRARRAAADFHETVTRLAGNDLLL
ELEATLRSRMRWLLGRHDDLGLVADEHERLYAAIAARDSARAEALAVAHIETSRALAARRADTRATGRTERDRPA

Sequences:

>Translated_235_residues
MGYQSGGAGARMGRMGFESESDRVTRQLRDQIVGGVRAPGSRLVERELAAELGVSRLPVREALRVLVAEGLVTARPRSWA
VVREFTPADVADLLEVRSAVDVLAFRLAAQRATRAGLAELRAVLDEEQAAARAGDAPRARRAAADFHETVTRLAGNDLLL
ELEATLRSRMRWLLGRHDDLGLVADEHERLYAAIAARDSARAEALAVAHIETSRALAARRADTRATGRTERDRPA
>Mature_234_residues
GYQSGGAGARMGRMGFESESDRVTRQLRDQIVGGVRAPGSRLVERELAAELGVSRLPVREALRVLVAEGLVTARPRSWAV
VREFTPADVADLLEVRSAVDVLAFRLAAQRATRAGLAELRAVLDEEQAAARAGDAPRARRAAADFHETVTRLAGNDLLLE
LEATLRSRMRWLLGRHDDLGLVADEHERLYAAIAARDSARAEALAVAHIETSRALAARRADTRATGRTERDRPA

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=221, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787821, Length=196, Percent_Identity=27.0408163265306, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87081914, Length=158, Percent_Identity=29.746835443038, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25574; Mature: 25443

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYQSGGAGARMGRMGFESESDRVTRQLRDQIVGGVRAPGSRLVERELAAELGVSRLPVR
CCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHH
EALRVLVAEGLVTARPRSWAVVREFTPADVADLLEVRSAVDVLAFRLAAQRATRAGLAEL
HHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVLDEEQAAARAGDAPRARRAAADFHETVTRLAGNDLLLELEATLRSRMRWLLGRHDDL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCC
GLVADEHERLYAAIAARDSARAEALAVAHIETSRALAARRADTRATGRTERDRPA
CCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GYQSGGAGARMGRMGFESESDRVTRQLRDQIVGGVRAPGSRLVERELAAELGVSRLPVR
CCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHH
EALRVLVAEGLVTARPRSWAVVREFTPADVADLLEVRSAVDVLAFRLAAQRATRAGLAEL
HHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVLDEEQAAARAGDAPRARRAAADFHETVTRLAGNDLLLELEATLRSRMRWLLGRHDDL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCC
GLVADEHERLYAAIAARDSARAEALAVAHIETSRALAARRADTRATGRTERDRPA
CCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]