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The map label for this gene is fadE36 [H]

Identifier: 54026323

GI number: 54026323

Start: 4514968

End: 4516230

Strand: Reverse

Name: fadE36 [H]

Synonym: nfa43520

Alternate gene names: 54026323

Gene position: 4516230-4514968 (Counterclockwise)

Preceding gene: 54026324

Following gene: 54026319

Centisome position: 75.01

GC content: 68.65

Gene sequence:

>1263_bases
GTGGATTTCGCACTGCCCGAGGAACTGACCGCCTACCTGGCCGAATTGGACGCCTTCATCGAGGCCGAGATCATTCCCCT
GGAACAGGCCGACGACAACATCCGGTTCTTCGACCACCGCCGCGAGGACGCGCGCACCGACTGGGAGCGCGGCGGCCTGC
CGACCGCGGAATGGGAAGCGCTGCTGGCCGAGTCGCGCCGCCGCGCCGACGCCGCCGGGCACTACCGGTACGCCTTCCCC
CAGGAGTTCGGCGGCCGGGACGGCACCAACCTGGGCATGGCCGTCATCCGCGAGCACCTGGCTCGCCGCGGCCTCGGCCT
GCACTGCGACCTGCAGAACGAGCACGCCATCGTCGCCAACAACGTCGGCCTGCTGTTGATGCTGGAGTACGGTTCGCCCG
CACAGCGGGCGCAGTGGGTGGACGGGCTGGCCGAGGGCACCAAGTTCTTCGCCTTCGGCATCACCGAGCCCGAGCACGGG
TCCGACGCCACGCACATGGAGACCACCGCCGTGCGCGACGGCGACCACTGGATCATCAACGGCACCAAAACCTGGAACAC
CGGCGTGCACATCGCCGACGCCGACCTGATCTTCGCCCGCACCTCCGGCCAGGCGGGTGACGGGCGCGGCATCACCGCGT
TCCTGGTGCCCACCGACGCTCCCGGCTTCACCGTCGAGGAGTACCTGTGGACGTTCAACATGCCCACCGACCACGCCCGC
ATCAGCCTCACCGACGTGCGGGTACCCGATGCGGCGATCTTCGGCGGGGAGGGCCGCGGCCTGGCGGTGGTGCAGCACTT
CTTCAACGAGAACCGCATCCGCCAGGCTGCCTCCAGCCTCGGCGCCGCGCAGTACTGCATCGACCAGGCGGTGGCCTACG
CCAAGGAGCGCAAGCCCTTCGGCAAGCCCCTGGCGGCCAACCAGGCGATCCAGTTCCCGCTGGTCGAGTTGCACACCCAG
TGCGAGATGCTGCGCGCGTTGATCCACAAGACCGCCTGGTCGATGGACACCTACGGCACCTTCGCCGTCTCCGAGCAGGT
CTCGATGTGCAACTACTGGGCCAACCGGCTGTGCTGTGCGGCCGCCGACCAGGCGATGCAGGTGCACGGCGGGCTCGGCT
ACTCCCGGCACAAGCCGTTCGAACACATCTACCGCCACCATCGCCGCTACCGGATCACCGAGGGCGCCGAGGAGATCCAG
ATGCGCCGCGTCGCGGGCTATCTGTTCGGCTTCATGGACCGGGCGAACGTCAAGGGCGTGTGA

Upstream 100 bases:

>100_bases
TCCGCGACATCGTCATGGCGGCCAGCGGGCGCCGGGTGTCGGAAATCGAATGGGATCTGCTCATGCAGATCCGGCCCGCC
GCACGAGCGTAGGAGAGAGC

Downstream 100 bases:

>100_bases
ACGCGGACGCTCACCGGTCCAGTCGCAGGGTGAAGAAGTACGGCTGCGGCGCGTCACGCTGATCCATCACGCCCAGCAGG
GTGTGCTCGTCGACGCGGCG

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDFALPEELTAYLAELDAFIEAEIIPLEQADDNIRFFDHRREDARTDWERGGLPTAEWEALLAESRRRADAAGHYRYAFP
QEFGGRDGTNLGMAVIREHLARRGLGLHCDLQNEHAIVANNVGLLLMLEYGSPAQRAQWVDGLAEGTKFFAFGITEPEHG
SDATHMETTAVRDGDHWIINGTKTWNTGVHIADADLIFARTSGQAGDGRGITAFLVPTDAPGFTVEEYLWTFNMPTDHAR
ISLTDVRVPDAAIFGGEGRGLAVVQHFFNENRIRQAASSLGAAQYCIDQAVAYAKERKPFGKPLAANQAIQFPLVELHTQ
CEMLRALIHKTAWSMDTYGTFAVSEQVSMCNYWANRLCCAAADQAMQVHGGLGYSRHKPFEHIYRHHRRYRITEGAEEIQ
MRRVAGYLFGFMDRANVKGV

Sequences:

>Translated_420_residues
MDFALPEELTAYLAELDAFIEAEIIPLEQADDNIRFFDHRREDARTDWERGGLPTAEWEALLAESRRRADAAGHYRYAFP
QEFGGRDGTNLGMAVIREHLARRGLGLHCDLQNEHAIVANNVGLLLMLEYGSPAQRAQWVDGLAEGTKFFAFGITEPEHG
SDATHMETTAVRDGDHWIINGTKTWNTGVHIADADLIFARTSGQAGDGRGITAFLVPTDAPGFTVEEYLWTFNMPTDHAR
ISLTDVRVPDAAIFGGEGRGLAVVQHFFNENRIRQAASSLGAAQYCIDQAVAYAKERKPFGKPLAANQAIQFPLVELHTQ
CEMLRALIHKTAWSMDTYGTFAVSEQVSMCNYWANRLCCAAADQAMQVHGGLGYSRHKPFEHIYRHHRRYRITEGAEEIQ
MRRVAGYLFGFMDRANVKGV
>Mature_420_residues
MDFALPEELTAYLAELDAFIEAEIIPLEQADDNIRFFDHRREDARTDWERGGLPTAEWEALLAESRRRADAAGHYRYAFP
QEFGGRDGTNLGMAVIREHLARRGLGLHCDLQNEHAIVANNVGLLLMLEYGSPAQRAQWVDGLAEGTKFFAFGITEPEHG
SDATHMETTAVRDGDHWIINGTKTWNTGVHIADADLIFARTSGQAGDGRGITAFLVPTDAPGFTVEEYLWTFNMPTDHAR
ISLTDVRVPDAAIFGGEGRGLAVVQHFFNENRIRQAASSLGAAQYCIDQAVAYAKERKPFGKPLAANQAIQFPLVELHTQ
CEMLRALIHKTAWSMDTYGTFAVSEQVSMCNYWANRLCCAAADQAMQVHGGLGYSRHKPFEHIYRHHRRYRITEGAEEIQ
MRRVAGYLFGFMDRANVKGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=333, Percent_Identity=35.4354354354354, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI187960098, Length=344, Percent_Identity=31.6860465116279, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4557231, Length=344, Percent_Identity=31.6860465116279, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI7656849, Length=349, Percent_Identity=30.945558739255, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4501859, Length=330, Percent_Identity=29.6969696969697, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI21361497, Length=405, Percent_Identity=27.6543209876543, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=27.1820448877805, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI211971008, Length=381, Percent_Identity=26.7716535433071, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI48976061, Length=381, Percent_Identity=26.7716535433071, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=26.1213720316623, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI226958412, Length=332, Percent_Identity=26.8072289156627, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226958414, Length=332, Percent_Identity=26.8072289156627, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI76496475, Length=425, Percent_Identity=27.2941176470588, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4557235, Length=425, Percent_Identity=27.2941176470588, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI7669494, Length=278, Percent_Identity=29.8561151079137, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4503943, Length=263, Percent_Identity=30.4182509505703, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081958, Length=407, Percent_Identity=27.027027027027, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786223, Length=360, Percent_Identity=25.8333333333333, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87081702, Length=278, Percent_Identity=26.2589928057554, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=351, Percent_Identity=31.9088319088319, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=29.8630136986301, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570075, Length=414, Percent_Identity=26.8115942028986, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17506239, Length=336, Percent_Identity=28.8690476190476, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=327, Percent_Identity=32.1100917431193, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71985184, Length=333, Percent_Identity=28.8288288288288, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=360, Percent_Identity=28.3333333333333, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=28.1818181818182, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17551932, Length=331, Percent_Identity=29.3051359516616, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=322, Percent_Identity=26.3975155279503, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=334, Percent_Identity=27.8443113772455, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71990804, Length=256, Percent_Identity=28.515625, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=297, Percent_Identity=27.9461279461279, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=29.8319327731092, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71982178, Length=224, Percent_Identity=31.6964285714286, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17534353, Length=310, Percent_Identity=26.4516129032258, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24660351, Length=332, Percent_Identity=31.9277108433735, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI21356377, Length=346, Percent_Identity=30.3468208092486, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24646207, Length=339, Percent_Identity=31.5634218289086, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24666513, Length=334, Percent_Identity=30.5389221556886, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=27.8645833333333, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281363737, Length=409, Percent_Identity=27.6283618581907, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI19920834, Length=218, Percent_Identity=33.9449541284404, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 46977; Mature: 46977

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFALPEELTAYLAELDAFIEAEIIPLEQADDNIRFFDHRREDARTDWERGGLPTAEWEA
CCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEHHCCCHHHCCCHHHCCCCHHHHHH
LLAESRRRADAAGHYRYAFPQEFGGRDGTNLGMAVIREHLARRGLGLHCDLQNEHAIVAN
HHHHHHHHHCCCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEE
NVGLLLMLEYGSPAQRAQWVDGLAEGTKFFAFGITEPEHGSDATHMETTAVRDGDHWIIN
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEE
GTKTWNTGVHIADADLIFARTSGQAGDGRGITAFLVPTDAPGFTVEEYLWTFNMPTDHAR
CCEECCCCEEEECCEEEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHEEEECCCCCCCE
ISLTDVRVPDAAIFGGEGRGLAVVQHFFNENRIRQAASSLGAAQYCIDQAVAYAKERKPF
EEEEEEECCCCEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKPLAANQAIQFPLVELHTQCEMLRALIHKTAWSMDTYGTFAVSEQVSMCNYWANRLCCA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHH
AADQAMQVHGGLGYSRHKPFEHIYRHHRRYRITEGAEEIQMRRVAGYLFGFMDRANVKGV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDFALPEELTAYLAELDAFIEAEIIPLEQADDNIRFFDHRREDARTDWERGGLPTAEWEA
CCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEHHCCCHHHCCCHHHCCCCHHHHHH
LLAESRRRADAAGHYRYAFPQEFGGRDGTNLGMAVIREHLARRGLGLHCDLQNEHAIVAN
HHHHHHHHHCCCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCEEEEE
NVGLLLMLEYGSPAQRAQWVDGLAEGTKFFAFGITEPEHGSDATHMETTAVRDGDHWIIN
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEE
GTKTWNTGVHIADADLIFARTSGQAGDGRGITAFLVPTDAPGFTVEEYLWTFNMPTDHAR
CCEECCCCEEEECCEEEEEECCCCCCCCCCEEEEEEECCCCCCCHHHHEEEECCCCCCCE
ISLTDVRVPDAAIFGGEGRGLAVVQHFFNENRIRQAASSLGAAQYCIDQAVAYAKERKPF
EEEEEEECCCCEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKPLAANQAIQFPLVELHTQCEMLRALIHKTAWSMDTYGTFAVSEQVSMCNYWANRLCCA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHH
AADQAMQVHGGLGYSRHKPFEHIYRHHRRYRITEGAEEIQMRRVAGYLFGFMDRANVKGV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]