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The map label for this gene is namA [H]

Identifier: 54026214

GI number: 54026214

Start: 4392345

End: 4393556

Strand: Reverse

Name: namA [H]

Synonym: nfa42430

Alternate gene names: 54026214

Gene position: 4393556-4392345 (Counterclockwise)

Preceding gene: 54026215

Following gene: 54026213

Centisome position: 72.97

GC content: 71.62

Gene sequence:

>1212_bases
ATGACCGAGATCTTCCACCCGGCCGCCCTCGGCCCGATCACCCTGCGCAATCGGGTGATCAAGGCCGCGACCTTCGAGGG
CCGCACCCCCGACGCGATCGCGAGCGAGGACCTGATCGCCTTCCACCGCGAGGTCGCCGCCGGCGGGGTCGGCATGACCA
CCGTCGCCTACTGCGCGGTCGCACCGGAGGGCCGCACCGAGCGCCGCCAGATCTGGCTGCGGCCGGAGGCGGTGCCGAGT
CTGCGCAAGCTCACCGACGCCGTGCACGCCGAGGGCGCGGCCGCCTGCGCCCAGATCGGGCATGCGGGTCCGGTCGCCGA
CGCGTCCTCCACCCGGCTGCCCGCTCTGGCGCCGAGCCCGATGTTCAGCCCGCTGGGCATGCGGAGGATGAAGGTGCCCG
CCGAGCACGAGATCGCCGACCTCGTCGCCGCCCACGCCCGCGCCGCGCTGCTCGCCGAGGAGGCCGGATTCGACGCGGTG
GAGATCCATTTCGGCCACAACTACCTCGCCAGCTCGTTCCTGAGCCCGTTGTTGAACCGGCGCACCGACGGCTACGGCGG
CACACTCGCCAACCGGGCCCGCTTCGCCCGCGAGATCGCCCGCGCCGTGCGCGCGGCCGTCGGCGGCCGCCTGGCCGTCC
TGGCGAAACTCAATATGGAAGACGGGGTTCCGGGCGGGCTCACGCTGCCGGAGTCCTTGCAGGTCGCCGCGTGGCTGGAA
CAGGACGGCAGCCTCGACGCGCTGGAGCTGACCGCGGGCAGCTCGCTGCTGAATCCGATGCTGCTCTTCCACGGCACGCC
GCCGCGCAAGTCCTTCGCGAACGTGCTGCCGGTGCCCGCGCGGTGGGGATTCCGCGTCGTCGGCAAGAAGTTCCTCCGGG
AGTACCCCTATCAGCCGGCCTATCTGCTCGAACGCGCCCGCCAGTTCCGTCGGGAACTGTCGTTGCCGTTGGTGTTGCTC
GGCGGTGTCACCGACCTGGACTCCATGCGGCTGGCGATGGCGGAGGGTTTCGACTTCGTCGCGATGGGCCGCGCACTGCT
GCGCGAACCCGATCTGCTGCAGCGCATCCAGGCCGACGCGGGCACCCGGTCGGCCTGCACCCACTGCAACGAATGCATGC
CGACCATCTACTCCGGAACACGGTGCGTGCTGCGGCTCGACAGCCCCGGCACCGTGCGCCACGCCGCGGCGTCGCAGATC
GAACCGGCCTGA

Upstream 100 bases:

>100_bases
GCGGCGCCGGAACCGACGACCGGCACCTGTCGGAGCACGCGGTGGCCACCCTGCGCGACTTCGTCGTGGCCGGATTGACC
GCTCCCCGAGGAGAATTGCG

Downstream 100 bases:

>100_bases
ACGTCCTCGTCGCCGCACCGCGTCGCACCGGAGGTGGTCGCCGACCGTGGTACCCAGTACGGTGTCGGGGCGGCCCCACC
GCCATCGGGGCCGTGCGGAG

Product: putative NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTEIFHPAALGPITLRNRVIKAATFEGRTPDAIASEDLIAFHREVAAGGVGMTTVAYCAVAPEGRTERRQIWLRPEAVPS
LRKLTDAVHAEGAAACAQIGHAGPVADASSTRLPALAPSPMFSPLGMRRMKVPAEHEIADLVAAHARAALLAEEAGFDAV
EIHFGHNYLASSFLSPLLNRRTDGYGGTLANRARFAREIARAVRAAVGGRLAVLAKLNMEDGVPGGLTLPESLQVAAWLE
QDGSLDALELTAGSSLLNPMLLFHGTPPRKSFANVLPVPARWGFRVVGKKFLREYPYQPAYLLERARQFRRELSLPLVLL
GGVTDLDSMRLAMAEGFDFVAMGRALLREPDLLQRIQADAGTRSACTHCNECMPTIYSGTRCVLRLDSPGTVRHAAASQI
EPA

Sequences:

>Translated_403_residues
MTEIFHPAALGPITLRNRVIKAATFEGRTPDAIASEDLIAFHREVAAGGVGMTTVAYCAVAPEGRTERRQIWLRPEAVPS
LRKLTDAVHAEGAAACAQIGHAGPVADASSTRLPALAPSPMFSPLGMRRMKVPAEHEIADLVAAHARAALLAEEAGFDAV
EIHFGHNYLASSFLSPLLNRRTDGYGGTLANRARFAREIARAVRAAVGGRLAVLAKLNMEDGVPGGLTLPESLQVAAWLE
QDGSLDALELTAGSSLLNPMLLFHGTPPRKSFANVLPVPARWGFRVVGKKFLREYPYQPAYLLERARQFRRELSLPLVLL
GGVTDLDSMRLAMAEGFDFVAMGRALLREPDLLQRIQADAGTRSACTHCNECMPTIYSGTRCVLRLDSPGTVRHAAASQI
EPA
>Mature_402_residues
TEIFHPAALGPITLRNRVIKAATFEGRTPDAIASEDLIAFHREVAAGGVGMTTVAYCAVAPEGRTERRQIWLRPEAVPSL
RKLTDAVHAEGAAACAQIGHAGPVADASSTRLPALAPSPMFSPLGMRRMKVPAEHEIADLVAAHARAALLAEEAGFDAVE
IHFGHNYLASSFLSPLLNRRTDGYGGTLANRARFAREIARAVRAAVGGRLAVLAKLNMEDGVPGGLTLPESLQVAAWLEQ
DGSLDALELTAGSSLLNPMLLFHGTPPRKSFANVLPVPARWGFRVVGKKFLREYPYQPAYLLERARQFRRELSLPLVLLG
GVTDLDSMRLAMAEGFDFVAMGRALLREPDLLQRIQADAGTRSACTHCNECMPTIYSGTRCVLRLDSPGTVRHAAASQIE
PA

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=390, Percent_Identity=30, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787939, Length=221, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17566914, Length=247, Percent_Identity=29.1497975708502, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=371, Percent_Identity=24.7978436657682, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=286, Percent_Identity=28.3216783216783, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=282, Percent_Identity=29.7872340425532, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=388, Percent_Identity=26.8041237113402, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559802, Length=277, Percent_Identity=30.3249097472924, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=268, Percent_Identity=26.1194029850746, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=224, Percent_Identity=28.125, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 43379; Mature: 43248

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIFHPAALGPITLRNRVIKAATFEGRTPDAIASEDLIAFHREVAAGGVGMTTVAYCAV
CCCCCCCCCCCCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHEE
APEGRTERRQIWLRPEAVPSLRKLTDAVHAEGAAACAQIGHAGPVADASSTRLPALAPSP
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MFSPLGMRRMKVPAEHEIADLVAAHARAALLAEEAGFDAVEIHFGHNYLASSFLSPLLNR
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHC
RTDGYGGTLANRARFAREIARAVRAAVGGRLAVLAKLNMEDGVPGGLTLPESLQVAAWLE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
QDGSLDALELTAGSSLLNPMLLFHGTPPRKSFANVLPVPARWGFRVVGKKFLREYPYQPA
CCCCCCEEEECCCHHHHCCHHEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHH
YLLERARQFRRELSLPLVLLGGVTDLDSMRLAMAEGFDFVAMGRALLREPDLLQRIQADA
HHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCC
GTRSACTHCNECMPTIYSGTRCVLRLDSPGTVRHAAASQIEPA
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TEIFHPAALGPITLRNRVIKAATFEGRTPDAIASEDLIAFHREVAAGGVGMTTVAYCAV
CCCCCCCCCCCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHEE
APEGRTERRQIWLRPEAVPSLRKLTDAVHAEGAAACAQIGHAGPVADASSTRLPALAPSP
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MFSPLGMRRMKVPAEHEIADLVAAHARAALLAEEAGFDAVEIHFGHNYLASSFLSPLLNR
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHC
RTDGYGGTLANRARFAREIARAVRAAVGGRLAVLAKLNMEDGVPGGLTLPESLQVAAWLE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
QDGSLDALELTAGSSLLNPMLLFHGTPPRKSFANVLPVPARWGFRVVGKKFLREYPYQPA
CCCCCCEEEECCCHHHHCCHHEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHH
YLLERARQFRRELSLPLVLLGGVTDLDSMRLAMAEGFDFVAMGRALLREPDLLQRIQADA
HHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCC
GTRSACTHCNECMPTIYSGTRCVLRLDSPGTVRHAAASQIEPA
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA