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The map label for this gene is polX [H]

Identifier: 54026152

GI number: 54026152

Start: 4330276

End: 4331331

Strand: Reverse

Name: polX [H]

Synonym: nfa41810

Alternate gene names: 54026152

Gene position: 4331331-4330276 (Counterclockwise)

Preceding gene: 54026153

Following gene: 54026150

Centisome position: 71.93

GC content: 72.44

Gene sequence:

>1056_bases
ATGGCCGCGCCCGGTACGGCGGCGGACCCGGCCCGGGCGCCGGGCCCGGTGGAGGCGCTGCGCGAGATCGGGTTCTGGCT
CGAGCGCGCCCGCGCGGAGACGCACCGGGTGAAGGCGTACCGGCGGGCCGCCGAGGTGGTGGCCGGACTGACCGAGCCGG
AGGTGGCCGCGCACGCGGCGGCCCACAGCTGGCAGGAGCTGCCCGGCATCGGACCCAAGACCGCCGCCGTGATCGCCCAG
GCCTGCGCCGGTGAGGTGCCCGCGTACCTGGCCGAGCTGCGCCGCGCCGCCGCGCCCATCGGGGCACCGGGAAAACCGTT
GCGGCAGTTGCTGCGCGGTGATCTGCACACCCATTCCAACTGGTCCGACGGCGGCAGCCCGATCGAGGAGATGATGCGGG
TGGCCGCCGCGCTCGGCCACGAATACTGCGCCCTCACCGATCATTCGCCGCGGCTCACGGTCGCCAACGGGCTGTCCGCG
GACCGGCTGCGCAGGCAACTGGACGTCGTCGCCGAGCTGAACGAGCGACTCGCCCCGTTCCGCATCCTCACCGGCATCGA
GGTCGACATCCTCGACGACGGCACCCTCGACCAGCGCGCCGATCTGCTCGCCGAGCTGGATGTGGTGGTGGCCAGCGTGC
ATTCGCACCTGCGCGCCGAGTCGGAGGTGATGACCAAACGCATGGTGTACGCGGTGGCCAATCCGCACGTGGACGTGCTC
GGCCACTGCACCGGCCGGCTCGTCACCGGCGGGCGCGGCACCCGGCCGGAGTCGACGTTCGACGCCGAGATGGTGTTCGA
GGCGTGCCGGCAGTACGGCACCGCGGTCGAGATCAACAGCCGACCCGAACGTCTCGACCCGCCGTCCCGGCTGCTCACCC
TCGCCGTCGAGATGGGCTGTCTCTTCGCGATCGACACCGACGCGCACGCGCCCGGCCAACTGGACTGGCTCGGTTACGGT
TGCGAGCGGGCCGTGGCCAACGGCGTTGCGCCGGAACGGGTGATCAACACCTGGCCGGTGGCGGACCTGCTCACCTGGAC
CCGGTCGCACTCCTGA

Upstream 100 bases:

>100_bases
GTCCGGCCCGCGGCTGCCCGAGCCCGCCAAGTTCCGGGTGATCACCAGCCGGGTGTTCGAGGACGGGGTGGCGTTCGTGA
AGTACAGCAGGATCAAGTAG

Downstream 100 bases:

>100_bases
TCCGGTGTGCGCCGGTGAATTCCGGCCGAACACCGCGGTAACACCCTGTCCCGCGGACCCTGCGGCGCCGACAATGATCG
GACGGCGGTGAAGCGGGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAAPGTAADPARAPGPVEALREIGFWLERARAETHRVKAYRRAAEVVAGLTEPEVAAHAAAHSWQELPGIGPKTAAVIAQ
ACAGEVPAYLAELRRAAAPIGAPGKPLRQLLRGDLHTHSNWSDGGSPIEEMMRVAAALGHEYCALTDHSPRLTVANGLSA
DRLRRQLDVVAELNERLAPFRILTGIEVDILDDGTLDQRADLLAELDVVVASVHSHLRAESEVMTKRMVYAVANPHVDVL
GHCTGRLVTGGRGTRPESTFDAEMVFEACRQYGTAVEINSRPERLDPPSRLLTLAVEMGCLFAIDTDAHAPGQLDWLGYG
CERAVANGVAPERVINTWPVADLLTWTRSHS

Sequences:

>Translated_351_residues
MAAPGTAADPARAPGPVEALREIGFWLERARAETHRVKAYRRAAEVVAGLTEPEVAAHAAAHSWQELPGIGPKTAAVIAQ
ACAGEVPAYLAELRRAAAPIGAPGKPLRQLLRGDLHTHSNWSDGGSPIEEMMRVAAALGHEYCALTDHSPRLTVANGLSA
DRLRRQLDVVAELNERLAPFRILTGIEVDILDDGTLDQRADLLAELDVVVASVHSHLRAESEVMTKRMVYAVANPHVDVL
GHCTGRLVTGGRGTRPESTFDAEMVFEACRQYGTAVEINSRPERLDPPSRLLTLAVEMGCLFAIDTDAHAPGQLDWLGYG
CERAVANGVAPERVINTWPVADLLTWTRSHS
>Mature_350_residues
AAPGTAADPARAPGPVEALREIGFWLERARAETHRVKAYRRAAEVVAGLTEPEVAAHAAAHSWQELPGIGPKTAAVIAQA
CAGEVPAYLAELRRAAAPIGAPGKPLRQLLRGDLHTHSNWSDGGSPIEEMMRVAAALGHEYCALTDHSPRLTVANGLSAD
RLRRQLDVVAELNERLAPFRILTGIEVDILDDGTLDQRADLLAELDVVVASVHSHLRAESEVMTKRMVYAVANPHVDVLG
HCTGRLVTGGRGTRPESTFDAEMVFEACRQYGTAVEINSRPERLDPPSRLLTLAVEMGCLFAIDTDAHAPGQLDWLGYGC
ERAVANGVAPERVINTWPVADLLTWTRSHS

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37843; Mature: 37712

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPGTAADPARAPGPVEALREIGFWLERARAETHRVKAYRRAAEVVAGLTEPEVAAHAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHSWQELPGIGPKTAAVIAQACAGEVPAYLAELRRAAAPIGAPGKPLRQLLRGDLHTHSN
HHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
WSDGGSPIEEMMRVAAALGHEYCALTDHSPRLTVANGLSADRLRRQLDVVAELNERLAPF
CCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCC
RILTGIEVDILDDGTLDQRADLLAELDVVVASVHSHLRAESEVMTKRMVYAVANPHVDVL
HHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GHCTGRLVTGGRGTRPESTFDAEMVFEACRQYGTAVEINSRPERLDPPSRLLTLAVEMGC
HCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCE
LFAIDTDAHAPGQLDWLGYGCERAVANGVAPERVINTWPVADLLTWTRSHS
EEEEECCCCCCCCCHHHCCCHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AAPGTAADPARAPGPVEALREIGFWLERARAETHRVKAYRRAAEVVAGLTEPEVAAHAA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AHSWQELPGIGPKTAAVIAQACAGEVPAYLAELRRAAAPIGAPGKPLRQLLRGDLHTHSN
HHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
WSDGGSPIEEMMRVAAALGHEYCALTDHSPRLTVANGLSADRLRRQLDVVAELNERLAPF
CCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCC
RILTGIEVDILDDGTLDQRADLLAELDVVVASVHSHLRAESEVMTKRMVYAVANPHVDVL
HHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GHCTGRLVTGGRGTRPESTFDAEMVFEACRQYGTAVEINSRPERLDPPSRLLTLAVEMGC
HCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHCE
LFAIDTDAHAPGQLDWLGYGCERAVANGVAPERVINTWPVADLLTWTRSHS
EEEEECCCCCCCCCHHHCCCHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]