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The map label for this gene is frr

Identifier: 54026099

GI number: 54026099

Start: 4276330

End: 4276887

Strand: Reverse

Name: frr

Synonym: nfa41280

Alternate gene names: 54026099

Gene position: 4276887-4276330 (Counterclockwise)

Preceding gene: 54026100

Following gene: 54026098

Centisome position: 71.03

GC content: 64.52

Gene sequence:

>558_bases
GTGATTGAAGAAGCGCTCTTCGACGCCGAGGAGAAGATGGAGAAGGCCGTCTCGGTGGCGAAGGACGATCTCGGGACCAT
CCGGACCGGCCGCGCGAATCCGGGCATGTTCGCCCGGGTGGTCGTGGACTACTACGGATCGCCCACGCCGGTCACCCAGA
TGTCCAGCATCACCGTGCCCGAACCGCGGATGGTGGTGATCAAGCCGTACGAGGCGGGGCAGCTCGGCGCGATCGAGACC
GCGATCCGCAACTCCGATCTCGGCGTGAATCCCACCAACAACGGTGACATCCTGCGCATCACCATCCCGCAGCTCACCGA
GGAGCGTCGCCGCGAACTGGTCAAGCAGGCCAAGGGCAAGGGCGAGGACGCGAAGGTCGCCATCCGCAATGTCCGTCGCA
AGGCGATGGACGAGCTGGCCCGCATCCAGAAGGATGGCGAGGCGGGCGAGGACGAGGTCGGGCGCGCCGAGAAGGAACTC
GACAAGACCACCGCCAAATACGTGAGCCAGATCGACGAACTGGTCAAGCACAAGGAAGCCGAACTCCTCGAGGTCTGA

Upstream 100 bases:

>100_bases
TCGCCCGAGCGGTCGCCGGTGAGAAGATCGGCACATTGGTTCGTTCCTGAGCCCGCGACTTGCGGATCATGACGATGACG
ACGCTGTGGAGGAAATGGTC

Downstream 100 bases:

>100_bases
GGCCAGATCCGAGGGCCCGCCCGGGCGGGGGACGAACGGAACGACGAGTGAGCGACGGGACAATCGTGGCCGAGAAAGCC
GCCGCCGAAGGTGCGGCCGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIEEALFDAEEKMEKAVSVAKDDLGTIRTGRANPGMFARVVVDYYGSPTPVTQMSSITVPEPRMVVIKPYEAGQLGAIET
AIRNSDLGVNPTNNGDILRITIPQLTEERRRELVKQAKGKGEDAKVAIRNVRRKAMDELARIQKDGEAGEDEVGRAEKEL
DKTTAKYVSQIDELVKHKEAELLEV

Sequences:

>Translated_185_residues
MIEEALFDAEEKMEKAVSVAKDDLGTIRTGRANPGMFARVVVDYYGSPTPVTQMSSITVPEPRMVVIKPYEAGQLGAIET
AIRNSDLGVNPTNNGDILRITIPQLTEERRRELVKQAKGKGEDAKVAIRNVRRKAMDELARIQKDGEAGEDEVGRAEKEL
DKTTAKYVSQIDELVKHKEAELLEV
>Mature_185_residues
MIEEALFDAEEKMEKAVSVAKDDLGTIRTGRANPGMFARVVVDYYGSPTPVTQMSSITVPEPRMVVIKPYEAGQLGAIET
AIRNSDLGVNPTNNGDILRITIPQLTEERRRELVKQAKGKGEDAKVAIRNVRRKAMDELARIQKDGEAGEDEVGRAEKEL
DKTTAKYVSQIDELVKHKEAELLEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=29.4444444444444, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI291042689, Length=135, Percent_Identity=32.5925925925926, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=41.8478260869565, Blast_Score=151, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=25.6983240223464, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NOCFA (Q5YS64)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120341.1
- ProteinModelPortal:   Q5YS64
- SMR:   Q5YS64
- GeneID:   3109683
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa41280
- NMPDR:   fig|247156.1.peg.3985
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   NFAR247156:NFA41280-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20508; Mature: 20508

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEEALFDAEEKMEKAVSVAKDDLGTIRTGRANPGMFARVVVDYYGSPTPVTQMSSITVP
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
EPRMVVIKPYEAGQLGAIETAIRNSDLGVNPTNNGDILRITIPQLTEERRRELVKQAKGK
CCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
GEDAKVAIRNVRRKAMDELARIQKDGEAGEDEVGRAEKELDKTTAKYVSQIDELVKHKEA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLEV
HHHCC
>Mature Secondary Structure
MIEEALFDAEEKMEKAVSVAKDDLGTIRTGRANPGMFARVVVDYYGSPTPVTQMSSITVP
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
EPRMVVIKPYEAGQLGAIETAIRNSDLGVNPTNNGDILRITIPQLTEERRRELVKQAKGK
CCCEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
GEDAKVAIRNVRRKAMDELARIQKDGEAGEDEVGRAEKELDKTTAKYVSQIDELVKHKEA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA