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The map label for this gene is ribF [H]

Identifier: 54025860

GI number: 54025860

Start: 4103286

End: 4104245

Strand: Reverse

Name: ribF [H]

Synonym: nfa38900

Alternate gene names: 54025860

Gene position: 4104245-4103286 (Counterclockwise)

Preceding gene: 54025861

Following gene: 54025858

Centisome position: 68.16

GC content: 70.42

Gene sequence:

>960_bases
GTGCAGAGATGGCGAAGTCTCGACGATGTGCCCGCGGACTGGGGTCGGTGTGTGCTCACGATCGGTGTTTTCGACGGGGT
GCACCGCGGCCACGCGCAACTGATCAGCAGAGCCGTGAAATCGGCCGCGGCACGGGGTGTTCCCGCCGTGCTGATGACCT
TCGACCCGCACCCGATGGAGGTGGTGCGGCCCGGCTCCCATCCCGCGCAGCTGACCACCCTCACCCGCCGGGCCGAACTG
GTCGAGGAACTGGGCATCGACGTGTTCTGCGTGATGCCGTTCACCCAGGACTTCATGAAGCTCACCCCCGCCCGCTACGT
GCACGACCTGCTGGTCGAGCGGCTGCACGTGGCCGAGGTGGTCGTCGGCGACAACTTCACCTTCGGCAAGAAGGCCGCGG
GCACCGTGGACACCATGCGGGAGCTGGGGCAGCGCTTCGGCTTCGAGGTCGACGGGGTCAAGCTGGTCGGCGAACACGCC
GTCACGTTCTCCTCCACCTACATCCGCGCCTGCGTCGACGCCGGCGACATGCGCGCGGCCGCCGAAGCGCTGGGCCGCCC
GCACCGCGTGGAGGGCGTGGTCGTGCACGGCGACGGCCGCGGCCGCGAACTCGGCTTCCCCACCGCCAACGTGGCGCCGC
CGATGTATGCCGCGATTCCCGCCGACGGCGTGTACGCGGGCTGGTTCACCGTGCTCGGGCCGGGGCCGACCATCGGCACC
GTGACGCCGGGGGAGCGCGCGATGGCGGCGATCTCGGTCGGCACCAACCCCACCTTCTCCGGCCGCGCCCGCACGGTGGA
GGCCTACGTCATCGACGGTCAGGCCGACCTGTACGGCCAGCACGTCGCCGTCGACTTCGTCGAGCACCTGCGCGGCATGG
AGAAATTCGACGGGCTGGACTCGCTGATCGCGGCGATGCGGCGCGACGTGGACAACGCCCGCCGGATCCTCACCGCCTGA

Upstream 100 bases:

>100_bases
TTGGAGAGCTTGTGTCCGGCCAATCTTGGAGCAAAGTTGGAATCGGGTGCTGATCCGTTCGTTTGGAGTTGCTCGTGAGC
TGCGAAGTAAGGTCTGAACT

Downstream 100 bases:

>100_bases
GCGGCGACTAGGGCAACTCCCGTTCCGGCACCGTCCACCGGTAGATCTGCCCGTCGCGCAACTCCACCGCCACCGGCGGC
TCGTCGGTGGGGTTGGCCGC

Product: bifunctional riboflavin kinase/FMN adenylyltransferase

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MQRWRSLDDVPADWGRCVLTIGVFDGVHRGHAQLISRAVKSAAARGVPAVLMTFDPHPMEVVRPGSHPAQLTTLTRRAEL
VEELGIDVFCVMPFTQDFMKLTPARYVHDLLVERLHVAEVVVGDNFTFGKKAAGTVDTMRELGQRFGFEVDGVKLVGEHA
VTFSSTYIRACVDAGDMRAAAEALGRPHRVEGVVVHGDGRGRELGFPTANVAPPMYAAIPADGVYAGWFTVLGPGPTIGT
VTPGERAMAAISVGTNPTFSGRARTVEAYVIDGQADLYGQHVAVDFVEHLRGMEKFDGLDSLIAAMRRDVDNARRILTA

Sequences:

>Translated_319_residues
MQRWRSLDDVPADWGRCVLTIGVFDGVHRGHAQLISRAVKSAAARGVPAVLMTFDPHPMEVVRPGSHPAQLTTLTRRAEL
VEELGIDVFCVMPFTQDFMKLTPARYVHDLLVERLHVAEVVVGDNFTFGKKAAGTVDTMRELGQRFGFEVDGVKLVGEHA
VTFSSTYIRACVDAGDMRAAAEALGRPHRVEGVVVHGDGRGRELGFPTANVAPPMYAAIPADGVYAGWFTVLGPGPTIGT
VTPGERAMAAISVGTNPTFSGRARTVEAYVIDGQADLYGQHVAVDFVEHLRGMEKFDGLDSLIAAMRRDVDNARRILTA
>Mature_319_residues
MQRWRSLDDVPADWGRCVLTIGVFDGVHRGHAQLISRAVKSAAARGVPAVLMTFDPHPMEVVRPGSHPAQLTTLTRRAEL
VEELGIDVFCVMPFTQDFMKLTPARYVHDLLVERLHVAEVVVGDNFTFGKKAAGTVDTMRELGQRFGFEVDGVKLVGEHA
VTFSSTYIRACVDAGDMRAAAEALGRPHRVEGVVVHGDGRGRELGFPTANVAPPMYAAIPADGVYAGWFTVLGPGPTIGT
VTPGERAMAAISVGTNPTFSGRARTVEAYVIDGQADLYGQHVAVDFVEHLRGMEKFDGLDSLIAAMRRDVDNARRILTA

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=136, Percent_Identity=33.0882352941176, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786208, Length=298, Percent_Identity=36.241610738255, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17541882, Length=134, Percent_Identity=33.5820895522388, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644927, Length=131, Percent_Identity=37.4045801526718, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 34520; Mature: 34520

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRWRSLDDVPADWGRCVLTIGVFDGVHRGHAQLISRAVKSAAARGVPAVLMTFDPHPME
CCCCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
VVRPGSHPAQLTTLTRRAELVEELGIDVFCVMPFTQDFMKLTPARYVHDLLVERLHVAEV
EECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCHHHHHHHHHHHHHHHHHE
VVGDNFTFGKKAAGTVDTMRELGQRFGFEVDGVKLVGEHAVTFSSTYIRACVDAGDMRAA
EECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHCCCHHHHH
AEALGRPHRVEGVVVHGDGRGRELGFPTANVAPPMYAAIPADGVYAGWFTVLGPGPTIGT
HHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEECEEEEECCCCCCCC
VTPGERAMAAISVGTNPTFSGRARTVEAYVIDGQADLYGQHVAVDFVEHLRGMEKFDGLD
CCCCCHHEEEEEECCCCCCCCCCEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHCCHH
SLIAAMRRDVDNARRILTA
HHHHHHHHCHHHHHHHHCC
>Mature Secondary Structure
MQRWRSLDDVPADWGRCVLTIGVFDGVHRGHAQLISRAVKSAAARGVPAVLMTFDPHPME
CCCCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
VVRPGSHPAQLTTLTRRAELVEELGIDVFCVMPFTQDFMKLTPARYVHDLLVERLHVAEV
EECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCHHHHHHHHHHHHHHHHHE
VVGDNFTFGKKAAGTVDTMRELGQRFGFEVDGVKLVGEHAVTFSSTYIRACVDAGDMRAA
EECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHCCCHHHHH
AEALGRPHRVEGVVVHGDGRGRELGFPTANVAPPMYAAIPADGVYAGWFTVLGPGPTIGT
HHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCEEECEEEEECCCCCCCC
VTPGERAMAAISVGTNPTFSGRARTVEAYVIDGQADLYGQHVAVDFVEHLRGMEKFDGLD
CCCCCHHEEEEEECCCCCCCCCCEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHCCHH
SLIAAMRRDVDNARRILTA
HHHHHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]