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The map label for this gene is hflX [H]

Identifier: 54025798

GI number: 54025798

Start: 4047438

End: 4049084

Strand: Reverse

Name: hflX [H]

Synonym: nfa38280

Alternate gene names: 54025798

Gene position: 4049084-4047438 (Counterclockwise)

Preceding gene: 54025799

Following gene: 54025797

Centisome position: 67.25

GC content: 70.73

Gene sequence:

>1647_bases
ATGCACGCCACCCCACCGGCGTGGCAGCATGGATGGTGTATGAGGAAATCAGAGACGTTCGACATCACTTCGACCTCCGG
CGCGAACGACGACGCCGACCAGGCCGAATTCACTTCTGACATCGATCTCACCGACGGCGACGTCACCGACGAGAACGATG
ACTACGCGCGCGAAGGCGACGTCCTCGCCGAGCGTGCCGCCCGCATGAAGCGCAACGGCTGGACCGCCGAGCCCACCGCG
GGCGAACTACAGCTCGAGGAACGCAGCTCGTTGCGCCGCGTCGCCGGGCTGTCCACCGAACTCACCGACATCACCGAGGT
CGAATACCGGCAGCTGCGCCTGGAACGGGTCGTGCTGGTCGGCGTGTGGACCTCGGGCACGGCCGCCCAGGCCGAGGCGA
GCATGGCCGAGCTGGCCGCCCTCGCCGAGACCGCCGGGTCGCAGGTGCTCGAGGCGCTGATCCAGCGCCGCGACAAGCCG
GACCCGGCCACCTACATCGGCTCCGGCAAGGCCGACGAACTGCGGGCCGTCGTGCTCGAGACCGGCGCCGACACGGTGAT
CTGCGACGGCGAGCTGACCCCGGCGCAGCTGACCGCGCTGGAGAAGGTGGTCAAGGTCAAGGTCATCGACCGGACCGCGC
TGATCCTGGACATCTTCGCCCAGCACGCCACCTCCAGCGAGGGCAAGGCGCAGGTCTCGCTGGCACAGATGGAGTACATG
CTGCCCCGGCTGCGCGGCTGGGGTGAGTCGATGTCCCGGCAGGCCGGTGGCCGCGCGGGCAGCAACGGCGGCGTGGGCCT
GCGCGGTCCCGGTGAGACGAAGATCGAGACCGATCGCCGTCGCATCCGCGAGCGCATGGCGAAACTGCGCCGGGAGATCC
GCGAGATGAAGACCGCCCGCGAGACCAAGCGGGCGCGCCGGGCGTCCTCGGGCATTCCCCAGGTCGCAATCGTCGGTTAC
ACCAACGCGGGCAAGTCGAGCCTGATGAACGCGCTCACCGGCTCCGGGGTCCTGGTGCAGGACGCGCTGTTCGCCACGCT
CGATCCGACCACCCGTCGGGCCGAGCTCGACGACGGGCGCGAGGTCGTGTTCACCGACACGGTCGGGTTCGTCCGGCACC
TGCCGACCCAGTTGGTCGAGGCGTTCCGTTCGACGCTGGAGGAGGTGACCGGCGCGGATCTGCTGCTGCACGTGGTCGAC
GGTTCCGATCCCGACCCGGCGGGCCAGATCAAGGCCGTGCGCGAGGTGATCGCCGACGTCATCAAGGAGTCCGGGGCCGC
GGCGCCGCCGGAACTGCTGGTGGTGAACAAGATCGATGCGATCTCGCCGATGCGGCGCACCGAGTTGCGCGGCCTGCTTC
CGGACGCGGAGTTCGTCTCCGCGCACACCGGTGCGGGCGTCGACGGGCTGCGGGCCCGGCTGAACGAGGTACTCGGTGGT
CTCGACGTGGAGGTCGGCGTGCTGCTGCCCTACACCCGGGGCGACCTGCTGGCCCGCGTGCACGCCGACGGCCGGATCCT
CGAATCGGCGCACGAGGAGGGCGGCACCCGGCTGCGGGCCCGTGTCCCGCACGCGCTGGCGGCGGCGCTGTCGGAGTACG
CGCACGCCGGTGCCGCCGGCGAGCCGGTCGGGGCCGAGCGGACATAG

Upstream 100 bases:

>100_bases
GGCTCGGCGTGGCTGCGCGGTCCGTCGGTGCTGGTCGCGACCGGTCGCCTCACGGCGGACTGGTGGCAGACGCTCGGATG
ATCACCCGGGCGAAATCGGA

Downstream 100 bases:

>100_bases
CACCGACGCGGAAAATAGAACCGACCGATACGTCCGGCGCCGAACAGCGCCGGACGTATCGGGTTCGCCACCGGTTCGCG
CTCACGGGCGAGCCATCGTC

Product: putative GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MHATPPAWQHGWCMRKSETFDITSTSGANDDADQAEFTSDIDLTDGDVTDENDDYAREGDVLAERAARMKRNGWTAEPTA
GELQLEERSSLRRVAGLSTELTDITEVEYRQLRLERVVLVGVWTSGTAAQAEASMAELAALAETAGSQVLEALIQRRDKP
DPATYIGSGKADELRAVVLETGADTVICDGELTPAQLTALEKVVKVKVIDRTALILDIFAQHATSSEGKAQVSLAQMEYM
LPRLRGWGESMSRQAGGRAGSNGGVGLRGPGETKIETDRRRIRERMAKLRREIREMKTARETKRARRASSGIPQVAIVGY
TNAGKSSLMNALTGSGVLVQDALFATLDPTTRRAELDDGREVVFTDTVGFVRHLPTQLVEAFRSTLEEVTGADLLLHVVD
GSDPDPAGQIKAVREVIADVIKESGAAAPPELLVVNKIDAISPMRRTELRGLLPDAEFVSAHTGAGVDGLRARLNEVLGG
LDVEVGVLLPYTRGDLLARVHADGRILESAHEEGGTRLRARVPHALAAALSEYAHAGAAGEPVGAERT

Sequences:

>Translated_548_residues
MHATPPAWQHGWCMRKSETFDITSTSGANDDADQAEFTSDIDLTDGDVTDENDDYAREGDVLAERAARMKRNGWTAEPTA
GELQLEERSSLRRVAGLSTELTDITEVEYRQLRLERVVLVGVWTSGTAAQAEASMAELAALAETAGSQVLEALIQRRDKP
DPATYIGSGKADELRAVVLETGADTVICDGELTPAQLTALEKVVKVKVIDRTALILDIFAQHATSSEGKAQVSLAQMEYM
LPRLRGWGESMSRQAGGRAGSNGGVGLRGPGETKIETDRRRIRERMAKLRREIREMKTARETKRARRASSGIPQVAIVGY
TNAGKSSLMNALTGSGVLVQDALFATLDPTTRRAELDDGREVVFTDTVGFVRHLPTQLVEAFRSTLEEVTGADLLLHVVD
GSDPDPAGQIKAVREVIADVIKESGAAAPPELLVVNKIDAISPMRRTELRGLLPDAEFVSAHTGAGVDGLRARLNEVLGG
LDVEVGVLLPYTRGDLLARVHADGRILESAHEEGGTRLRARVPHALAAALSEYAHAGAAGEPVGAERT
>Mature_548_residues
MHATPPAWQHGWCMRKSETFDITSTSGANDDADQAEFTSDIDLTDGDVTDENDDYAREGDVLAERAARMKRNGWTAEPTA
GELQLEERSSLRRVAGLSTELTDITEVEYRQLRLERVVLVGVWTSGTAAQAEASMAELAALAETAGSQVLEALIQRRDKP
DPATYIGSGKADELRAVVLETGADTVICDGELTPAQLTALEKVVKVKVIDRTALILDIFAQHATSSEGKAQVSLAQMEYM
LPRLRGWGESMSRQAGGRAGSNGGVGLRGPGETKIETDRRRIRERMAKLRREIREMKTARETKRARRASSGIPQVAIVGY
TNAGKSSLMNALTGSGVLVQDALFATLDPTTRRAELDDGREVVFTDTVGFVRHLPTQLVEAFRSTLEEVTGADLLLHVVD
GSDPDPAGQIKAVREVIADVIKESGAAAPPELLVVNKIDAISPMRRTELRGLLPDAEFVSAHTGAGVDGLRARLNEVLGG
LDVEVGVLLPYTRGDLLARVHADGRILESAHEEGGTRLRARVPHALAAALSEYAHAGAAGEPVGAERT

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=213, Percent_Identity=36.150234741784, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124267, Length=213, Percent_Identity=36.150234741784, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124171, Length=213, Percent_Identity=36.150234741784, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124169, Length=213, Percent_Identity=36.150234741784, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310133116, Length=221, Percent_Identity=36.1990950226244, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310133118, Length=221, Percent_Identity=36.1990950226244, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790615, Length=416, Percent_Identity=41.5865384615385, Blast_Score=278, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=295, Percent_Identity=32.5423728813559, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24650079, Length=324, Percent_Identity=34.8765432098765, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 58930; Mature: 58930

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHATPPAWQHGWCMRKSETFDITSTSGANDDADQAEFTSDIDLTDGDVTDENDDYAREGD
CCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHH
VLAERAARMKRNGWTAEPTAGELQLEERSSLRRVAGLSTELTDITEVEYRQLRLERVVLV
HHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEE
GVWTSGTAAQAEASMAELAALAETAGSQVLEALIQRRDKPDPATYIGSGKADELRAVVLE
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHEEEEEE
TGADTVICDGELTPAQLTALEKVVKVKVIDRTALILDIFAQHATSSEGKAQVSLAQMEYM
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LPRLRGWGESMSRQAGGRAGSNGGVGLRGPGETKIETDRRRIRERMAKLRREIREMKTAR
HHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETKRARRASSGIPQVAIVGYTNAGKSSLMNALTGSGVLVQDALFATLDPTTRRAELDDGR
HHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCCCCCCC
EVVFTDTVGFVRHLPTQLVEAFRSTLEEVTGADLLLHVVDGSDPDPAGQIKAVREVIADV
EEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
IKESGAAAPPELLVVNKIDAISPMRRTELRGLLPDAEFVSAHTGAGVDGLRARLNEVLGG
HHHCCCCCCCCEEEEECCHHCCCHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHCC
LDVEVGVLLPYTRGDLLARVHADGRILESAHEEGGTRLRARVPHALAAALSEYAHAGAAG
CCEEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCEEHHHCCHHHHHHHHHHHHCCCCC
EPVGAERT
CCCCCCCC
>Mature Secondary Structure
MHATPPAWQHGWCMRKSETFDITSTSGANDDADQAEFTSDIDLTDGDVTDENDDYAREGD
CCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHH
VLAERAARMKRNGWTAEPTAGELQLEERSSLRRVAGLSTELTDITEVEYRQLRLERVVLV
HHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEE
GVWTSGTAAQAEASMAELAALAETAGSQVLEALIQRRDKPDPATYIGSGKADELRAVVLE
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHEEEEEE
TGADTVICDGELTPAQLTALEKVVKVKVIDRTALILDIFAQHATSSEGKAQVSLAQMEYM
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LPRLRGWGESMSRQAGGRAGSNGGVGLRGPGETKIETDRRRIRERMAKLRREIREMKTAR
HHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETKRARRASSGIPQVAIVGYTNAGKSSLMNALTGSGVLVQDALFATLDPTTRRAELDDGR
HHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHCCCCCCCCCCCCCC
EVVFTDTVGFVRHLPTQLVEAFRSTLEEVTGADLLLHVVDGSDPDPAGQIKAVREVIADV
EEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
IKESGAAAPPELLVVNKIDAISPMRRTELRGLLPDAEFVSAHTGAGVDGLRARLNEVLGG
HHHCCCCCCCCEEEEECCHHCCCHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHCC
LDVEVGVLLPYTRGDLLARVHADGRILESAHEEGGTRLRARVPHALAAALSEYAHAGAAG
CCEEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCCEEHHHCCHHHHHHHHHHHHCCCCC
EPVGAERT
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]