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The map label for this gene is 54025797

Identifier: 54025797

GI number: 54025797

Start: 4046254

End: 4047114

Strand: Reverse

Name: 54025797

Synonym: nfa38270

Alternate gene names: NA

Gene position: 4047114-4046254 (Counterclockwise)

Preceding gene: 54025798

Following gene: 54025796

Centisome position: 67.21

GC content: 70.73

Gene sequence:

>861_bases
ATGCCTGAATCCTCGCCCGCCGAGGCGGTGCTGACCGACGGCGCGCCACTGCAGGTGCGACTCGCGGACACCGACATCCG
AATTCTGGAAACACTGCTCGCGCCGCTGCGCGCGTGGACGAGTCCGCGTTTCTACGGCCTGGACAACATCCCGGCCGAAG
GGCCCGTGCTACTCGTCGGCAACCACAATCTGCTCGGCGCGATCGACGCGCCGCTGCTGCTGCCCGAGGTCTTGCGCCAC
CGGGGCAGGCTCATCCGCGGCCTGGCCGAACACGTGCTCATCGCGGTGCCGGGCGTGCGGCACTTCCTGCACCGGTACGG
GTCGGTGCGCGGCACCCGCGGCAACTGCCTGGCGCTGCTCGAACGCGGCGAGGCGGTGATCGTCTTTCCCGGCGGCGGGC
GCGAGGCGGTGCGCCGCAAGGGGGAGAAGTACGTGCTCAAGTGGGAGGGTCGTACCGGCTTCGCGCACATGGCGCTCACC
GCGGGCGTGCCGATCGTGCCGGTGGCGATGATCGGCGTCGATGACGCCTTCGACATCGTCGTGGACGGCGATCATCCGCT
GATGCGGCCGGTGCGCTGGACCGTGGAGGCGCTCGGCCTCAAGCGCGATCTCACCCCGCCGCTGGTGCGCGGGATCGGGC
TCACCCCGATTCCGCGCCCGGAACGGTTCTACTTCTCCGCCGGTGCGCCGATCGACCCCGCGCCGTGGGTCGAGTCGGAC
AATCCGGAATCCGCCGCCGCGGACCTGCGCGACGTGGTGCGCAAGGCCCTCGAGGAGGAGATCCGGTTCCTGCTCGCCGA
ACGCGACCGCGACTCCGGTCGTACGCTCGTCGGCCGGATGAAGGATCTGCTCCGCCGCTGA

Upstream 100 bases:

>100_bases
CTGGGTAGTCTGGGTCACAGCCGCGGTTCTCGCGGACCAGGGGACATCACATTCCGTACGACGACGTGCAGGGATCCGAC
ATGCGATGGGGTAGCCACCT

Downstream 100 bases:

>100_bases
ATCGGGGACATTCCCCATTTCCTCCCCGATCTTCCGTCGGTCCGGCAAACATCCGGCGTGCCGTGCGTAGCGTGAGGGAA
TGGTGTGGAGCGGTACCCGA

Product: putative acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPESSPAEAVLTDGAPLQVRLADTDIRILETLLAPLRAWTSPRFYGLDNIPAEGPVLLVGNHNLLGAIDAPLLLPEVLRH
RGRLIRGLAEHVLIAVPGVRHFLHRYGSVRGTRGNCLALLERGEAVIVFPGGGREAVRRKGEKYVLKWEGRTGFAHMALT
AGVPIVPVAMIGVDDAFDIVVDGDHPLMRPVRWTVEALGLKRDLTPPLVRGIGLTPIPRPERFYFSAGAPIDPAPWVESD
NPESAAADLRDVVRKALEEEIRFLLAERDRDSGRTLVGRMKDLLRR

Sequences:

>Translated_286_residues
MPESSPAEAVLTDGAPLQVRLADTDIRILETLLAPLRAWTSPRFYGLDNIPAEGPVLLVGNHNLLGAIDAPLLLPEVLRH
RGRLIRGLAEHVLIAVPGVRHFLHRYGSVRGTRGNCLALLERGEAVIVFPGGGREAVRRKGEKYVLKWEGRTGFAHMALT
AGVPIVPVAMIGVDDAFDIVVDGDHPLMRPVRWTVEALGLKRDLTPPLVRGIGLTPIPRPERFYFSAGAPIDPAPWVESD
NPESAAADLRDVVRKALEEEIRFLLAERDRDSGRTLVGRMKDLLRR
>Mature_285_residues
PESSPAEAVLTDGAPLQVRLADTDIRILETLLAPLRAWTSPRFYGLDNIPAEGPVLLVGNHNLLGAIDAPLLLPEVLRHR
GRLIRGLAEHVLIAVPGVRHFLHRYGSVRGTRGNCLALLERGEAVIVFPGGGREAVRRKGEKYVLKWEGRTGFAHMALTA
GVPIVPVAMIGVDDAFDIVVDGDHPLMRPVRWTVEALGLKRDLTPPLVRGIGLTPIPRPERFYFSAGAPIDPAPWVESDN
PESAAADLRDVVRKALEEEIRFLLAERDRDSGRTLVGRMKDLLRR

Specific function: Unknown

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML2427 [H]

Homologues:

Organism=Homo sapiens, GI22748883, Length=126, Percent_Identity=31.7460317460317, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25148136, Length=245, Percent_Identity=23.265306122449, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996505, Length=242, Percent_Identity=24.3801652892562, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161077744, Length=133, Percent_Identity=33.8345864661654, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR016676 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: NA

Molecular weight: Translated: 31435; Mature: 31304

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESSPAEAVLTDGAPLQVRLADTDIRILETLLAPLRAWTSPRFYGLDNIPAEGPVLLVG
CCCCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEEE
NHNLLGAIDAPLLLPEVLRHRGRLIRGLAEHVLIAVPGVRHFLHRYGSVRGTRGNCLALL
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCEEEEE
ERGEAVIVFPGGGREAVRRKGEKYVLKWEGRTGFAHMALTAGVPIVPVAMIGVDDAFDIV
ECCCEEEEECCCCHHHHHCCCCEEEEEECCCCCEEHHHHHCCCCEEEEEEEECCCCEEEE
VDGDHPLMRPVRWTVEALGLKRDLTPPLVRGIGLTPIPRPERFYFSAGAPIDPAPWVESD
ECCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
NPESAAADLRDVVRKALEEEIRFLLAERDRDSGRTLVGRMKDLLRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PESSPAEAVLTDGAPLQVRLADTDIRILETLLAPLRAWTSPRFYGLDNIPAEGPVLLVG
CCCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCEEEEE
NHNLLGAIDAPLLLPEVLRHRGRLIRGLAEHVLIAVPGVRHFLHRYGSVRGTRGNCLALL
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCEEEEE
ERGEAVIVFPGGGREAVRRKGEKYVLKWEGRTGFAHMALTAGVPIVPVAMIGVDDAFDIV
ECCCEEEEECCCCHHHHHCCCCEEEEEECCCCCEEHHHHHCCCCEEEEEEEECCCCEEEE
VDGDHPLMRPVRWTVEALGLKRDLTPPLVRGIGLTPIPRPERFYFSAGAPIDPAPWVESD
ECCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
NPESAAADLRDVVRKALEEEIRFLLAERDRDSGRTLVGRMKDLLRR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]