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The map label for this gene is nrdR

Identifier: 54025768

GI number: 54025768

Start: 4021634

End: 4022104

Strand: Reverse

Name: nrdR

Synonym: nfa37980

Alternate gene names: 54025768

Gene position: 4022104-4021634 (Counterclockwise)

Preceding gene: 54025769

Following gene: 54025766

Centisome position: 66.8

GC content: 72.19

Gene sequence:

>471_bases
ATGCACTGCCCGTACTGCCGACACCCCGACTCCCGGGTCGTCGACTCGCGCGAGGCCGAGGAAGGTGCGGCCATCCGCCG
TCGGCGCTCCTGTCCGAATTGCGGGCGGCGGTTCACCACGGTCGAGACCGCCATCCTGTCGGTGGTGAAACGCAGCGGCG
TCACCGAGCCGTTCAGTCGGGAGAAGGTCATCCGTGGCGTGCGGCGCGCGTGCCAGGGCCGCGAGGTCGACGACGACGCG
CTGAACCTGCTCGCGCAGCAGGTGGAGGACGCGGTGCGGGCCAAGGGCTCGCCCGAGGTGCCCAGTCACGAGGTCGGCCT
GGCCATCCTCGGCCCGCTGCGCGACCTGGACGAGGTCGCCTACCTGCGCTTCGCCTCGGTGTACCGGTCCTTCACCTCGG
CCGAGGACTTCGAGCGCGAGATCAGCGAGATGCGCGCGGCGCGGGCGCGCGCGGGCGCGACAGCCGACTGA

Upstream 100 bases:

>100_bases
CGACATACTGCCTACCCGCCTGGACACCTGCTCGCCGGGCTCGGCCTCCCGACCGGAGGGCGCATCCGCCGCGAGCGCAC
GCATCGACGAAGGATCTCGG

Downstream 100 bases:

>100_bases
GCGGGCTCGGCGGCAGACCGCGGCTCGGTTCAGCGCCGGACCGCGGCTCGGTTCAGCGCCGGACCGCGGCTCGGTTCAGC
GCCGGACCGCGGCGATGGCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MHCPYCRHPDSRVVDSREAEEGAAIRRRRSCPNCGRRFTTVETAILSVVKRSGVTEPFSREKVIRGVRRACQGREVDDDA
LNLLAQQVEDAVRAKGSPEVPSHEVGLAILGPLRDLDEVAYLRFASVYRSFTSAEDFEREISEMRAARARAGATAD

Sequences:

>Translated_156_residues
MHCPYCRHPDSRVVDSREAEEGAAIRRRRSCPNCGRRFTTVETAILSVVKRSGVTEPFSREKVIRGVRRACQGREVDDDA
LNLLAQQVEDAVRAKGSPEVPSHEVGLAILGPLRDLDEVAYLRFASVYRSFTSAEDFEREISEMRAARARAGATAD
>Mature_156_residues
MHCPYCRHPDSRVVDSREAEEGAAIRRRRSCPNCGRRFTTVETAILSVVKRSGVTEPFSREKVIRGVRRACQGREVDDDA
LNLLAQQVEDAVRAKGSPEVPSHEVGLAILGPLRDLDEVAYLRFASVYRSFTSAEDFEREISEMRAARARAGATAD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=44.8979591836735, Blast_Score=130, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_NOCFA (Q5YT45)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120010.1
- GeneID:   3108553
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa37980
- NMPDR:   fig|247156.1.peg.3699
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   NFAR247156:NFA37980-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17377; Mature: 17377

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPYCRHPDSRVVDSREAEEGAAIRRRRSCPNCGRRFTTVETAILSVVKRSGVTEPFSR
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
EKVIRGVRRACQGREVDDDALNLLAQQVEDAVRAKGSPEVPSHEVGLAILGPLRDLDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
YLRFASVYRSFTSAEDFEREISEMRAARARAGATAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHCPYCRHPDSRVVDSREAEEGAAIRRRRSCPNCGRRFTTVETAILSVVKRSGVTEPFSR
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
EKVIRGVRRACQGREVDDDALNLLAQQVEDAVRAKGSPEVPSHEVGLAILGPLRDLDEVA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
YLRFASVYRSFTSAEDFEREISEMRAARARAGATAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA