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The map label for this gene is ygjG [C]

Identifier: 54025765

GI number: 54025765

Start: 4015484

End: 4016707

Strand: Reverse

Name: ygjG [C]

Synonym: nfa37950

Alternate gene names: 54025765

Gene position: 4016707-4015484 (Counterclockwise)

Preceding gene: 54025766

Following gene: 54025764

Centisome position: 66.71

GC content: 71.65

Gene sequence:

>1224_bases
ATGAACGCCTTGTGGCATGGATTCGCCGATATGGGCGCCGTCGCACGCGACGGCGCGTTCGTGGTGGCCCGCGGTGCGGG
CGCCTACGTCTACGACGAGGCGGGCAACCGCTATCTCGACGCCACCGCGGGCCTGTGGTTCACCAACGTCGGCCACGGCC
GGGCCGAGATCGCCGACGCCGTCGCCGCCCAGCTGCGGCGGATCGCGCACTACTCGAACTTCGGCGACATCGCCGAGCCG
CCGACCCGGGAACTGGCCGAACGGCTTTCGGCGATCGCGCCGATCCCGGGCAGCAAGATCTTCTTCACCTCCGGCGGTTC
CGACTCGGTGGACACCGCCGCGAAGTTCGCCCGCCGCTACTGGCACGAGGTCGGCAGGCCGGGCAAGACCATCGTGGTGG
GCAGGCAGCGCGCCTACCACGGCATGCACGTCGCGGGCACCGCGCTGTCGGGCCTGCCGCCGAACCGGGACGGCTACGGC
GAACTCATGCCCGACGCGCGCACGGTCGACTGGGACGACCCCAAGGGGCTGCTCGCGCTGATCGAGGAGGTCGGCGCCGA
GCGGATCGCGGCCTTCTTCTGCGAACCGATCATCGGCGCGGGCGGGGTGTACCTGCCACCGGAGGGGTATCTGACGGAGG
TGCGGGCGATCTGCGCCGACCACGACATCCTCTTCGTCGCCGACGAGGTGGTCACCGGCTTCGGCCGCATCGGCGGCTCC
TGGTTCGCCTCCAGCCGGTTCGACCTCCGCCCGGACCTGATGACCACCGCGAAGGGCCTCACCAGCGGCTATCTGCCGAT
GGGCGCGGTGTTCATCGCGCCGCACCTGGCCGAGCCGTTCTTCGCCGGTGGGGTGTGGTGGCGCCACGGCTACACCTACG
GCGGACACGCCGCCTCCGCCGCGGCCGCACTGGCCAATCTGGACATCCTCGAGCGCGAGAACCTGCTCGCCGAGGCGACG
CGACTGGAGGCTACCCTGCACGCCGAGCTGGCTCCGCTGGCACAGCATCCACGGGTCGCCGAGGTGCGCAGCGGGTTGGG
CGCGGTCGCCGCCGTCCAGCTCGCCGATCCCGCCGAAGCGCCCGCCTTCGTCAAAGCCCTACGGGCGGAAGGTGTGTCGA
GCCGGGCCGCGGGTCAGGGGGCATTGCAGATCTCGCCCGCGTTCGTCATGACCGACGAGCAGGTTCGCGAGCTGGCGGCC
GCGTTCGCCCGCGCCCTGGGCTGA

Upstream 100 bases:

>100_bases
CGGCGGTGGGCGGGTTCGCCGCGCGCGGGCGCGCGCCGAGTCCGGCGCTGTGAGCTGGGCCGACACCGGGGCGCCACCGG
CATAGGGTAGAGGTGGTGTC

Downstream 100 bases:

>100_bases
GCGCCGCCGCCGTGGGGTCGGGCACTCGACGCGGGCACCCGACAGGCCATACTGTGAGGGCAGATGCCCGCACTCCGCGT
GCGGGGTTTCGCGGGCCGGT

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNALWHGFADMGAVARDGAFVVARGAGAYVYDEAGNRYLDATAGLWFTNVGHGRAEIADAVAAQLRRIAHYSNFGDIAEP
PTRELAERLSAIAPIPGSKIFFTSGGSDSVDTAAKFARRYWHEVGRPGKTIVVGRQRAYHGMHVAGTALSGLPPNRDGYG
ELMPDARTVDWDDPKGLLALIEEVGAERIAAFFCEPIIGAGGVYLPPEGYLTEVRAICADHDILFVADEVVTGFGRIGGS
WFASSRFDLRPDLMTTAKGLTSGYLPMGAVFIAPHLAEPFFAGGVWWRHGYTYGGHAASAAAALANLDILERENLLAEAT
RLEATLHAELAPLAQHPRVAEVRSGLGAVAAVQLADPAEAPAFVKALRAEGVSSRAAGQGALQISPAFVMTDEQVRELAA
AFARALG

Sequences:

>Translated_407_residues
MNALWHGFADMGAVARDGAFVVARGAGAYVYDEAGNRYLDATAGLWFTNVGHGRAEIADAVAAQLRRIAHYSNFGDIAEP
PTRELAERLSAIAPIPGSKIFFTSGGSDSVDTAAKFARRYWHEVGRPGKTIVVGRQRAYHGMHVAGTALSGLPPNRDGYG
ELMPDARTVDWDDPKGLLALIEEVGAERIAAFFCEPIIGAGGVYLPPEGYLTEVRAICADHDILFVADEVVTGFGRIGGS
WFASSRFDLRPDLMTTAKGLTSGYLPMGAVFIAPHLAEPFFAGGVWWRHGYTYGGHAASAAAALANLDILERENLLAEAT
RLEATLHAELAPLAQHPRVAEVRSGLGAVAAVQLADPAEAPAFVKALRAEGVSSRAAGQGALQISPAFVMTDEQVRELAA
AFARALG
>Mature_407_residues
MNALWHGFADMGAVARDGAFVVARGAGAYVYDEAGNRYLDATAGLWFTNVGHGRAEIADAVAAQLRRIAHYSNFGDIAEP
PTRELAERLSAIAPIPGSKIFFTSGGSDSVDTAAKFARRYWHEVGRPGKTIVVGRQRAYHGMHVAGTALSGLPPNRDGYG
ELMPDARTVDWDDPKGLLALIEEVGAERIAAFFCEPIIGAGGVYLPPEGYLTEVRAICADHDILFVADEVVTGFGRIGGS
WFASSRFDLRPDLMTTAKGLTSGYLPMGAVFIAPHLAEPFFAGGVWWRHGYTYGGHAASAAAALANLDILERENLLAEAT
RLEATLHAELAPLAQHPRVAEVRSGLGAVAAVQLADPAEAPAFVKALRAEGVSSRAAGQGALQISPAFVMTDEQVRELAA
AFARALG

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=28.90625, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=28.2660332541568, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=28.2660332541568, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=30.6122448979592, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI13994255, Length=371, Percent_Identity=26.9541778975741, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=29.951690821256, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=27.9898218829517, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI145693181, Length=387, Percent_Identity=29.1989664082687, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786991, Length=419, Percent_Identity=30.0715990453461, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789759, Length=391, Percent_Identity=28.9002557544757, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=31.0945273631841, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787560, Length=380, Percent_Identity=31.8421052631579, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=29.5514511873351, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25144271, Length=393, Percent_Identity=26.972010178117, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=437, Percent_Identity=27.2311212814645, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=281, Percent_Identity=27.7580071174377, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=25.1141552511416, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324432, Length=400, Percent_Identity=26.5, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=24.4444444444444, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6324386, Length=423, Percent_Identity=25.2955082742317, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357415, Length=382, Percent_Identity=28.0104712041885, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356575, Length=425, Percent_Identity=28.7058823529412, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI161085790, Length=398, Percent_Identity=28.391959798995, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28574759, Length=398, Percent_Identity=28.391959798995, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 43124; Mature: 43124

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00137 SUBTILASE_HIS ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALWHGFADMGAVARDGAFVVARGAGAYVYDEAGNRYLDATAGLWFTNVGHGRAEIADA
CCCHHHCHHHHCHHHCCCCEEEEECCCCEEEECCCCEEEECCCCEEEECCCCCHHHHHHH
VAAQLRRIAHYSNFGDIAEPPTRELAERLSAIAPIPGSKIFFTSGGSDSVDTAAKFARRY
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHH
WHEVGRPGKTIVVGRQRAYHGMHVAGTALSGLPPNRDGYGELMPDARTVDWDDPKGLLAL
HHHHCCCCCEEEEECHHHHCCCEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
IEEVGAERIAAFFCEPIIGAGGVYLPPEGYLTEVRAICADHDILFVADEVVTGFGRIGGS
HHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCC
WFASSRFDLRPDLMTTAKGLTSGYLPMGAVFIAPHLAEPFFAGGVWWRHGYTYGGHAASA
HHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCHHHCCCCCCCHHHHH
AAALANLDILERENLLAEATRLEATLHAELAPLAQHPRVAEVRSGLGAVAAVQLADPAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCC
PAFVKALRAEGVSSRAAGQGALQISPAFVMTDEQVRELAAAFARALG
HHHHHHHHHCCCCCCCCCCCCEEECCEEEECHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNALWHGFADMGAVARDGAFVVARGAGAYVYDEAGNRYLDATAGLWFTNVGHGRAEIADA
CCCHHHCHHHHCHHHCCCCEEEEECCCCEEEECCCCEEEECCCCEEEECCCCCHHHHHHH
VAAQLRRIAHYSNFGDIAEPPTRELAERLSAIAPIPGSKIFFTSGGSDSVDTAAKFARRY
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHH
WHEVGRPGKTIVVGRQRAYHGMHVAGTALSGLPPNRDGYGELMPDARTVDWDDPKGLLAL
HHHHCCCCCEEEEECHHHHCCCEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
IEEVGAERIAAFFCEPIIGAGGVYLPPEGYLTEVRAICADHDILFVADEVVTGFGRIGGS
HHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCC
WFASSRFDLRPDLMTTAKGLTSGYLPMGAVFIAPHLAEPFFAGGVWWRHGYTYGGHAASA
HHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCHHHCCCCCCCHHHHH
AAALANLDILERENLLAEATRLEATLHAELAPLAQHPRVAEVRSGLGAVAAVQLADPAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCCC
PAFVKALRAEGVSSRAAGQGALQISPAFVMTDEQVRELAAAFARALG
HHHHHHHHHCCCCCCCCCCCCEEECCEEEECHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]