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The map label for this gene is aroE [H]

Identifier: 54025611

GI number: 54025611

Start: 3851940

End: 3852761

Strand: Reverse

Name: aroE [H]

Synonym: nfa36410

Alternate gene names: 54025611

Gene position: 3852761-3851940 (Counterclockwise)

Preceding gene: 54025612

Following gene: 54025610

Centisome position: 63.99

GC content: 75.3

Gene sequence:

>822_bases
GTGGGCGCTGACGCGACGACTCCCCGGCGGGCGGCGGTGCTCGGCAAGCCCATCGGGCATTCCCGCTCACCGCAGCTGCA
CCTGGCCGCCTACCGCGCGCTGGGCCTGGACTGGACCTACGACCGCATCGAATGCGATGCCGCGCAGCTGCCCGGCCTGG
TCGACGGGCTCGGCCCGGAATGGGTCGGCCTCTCGGTCACCATGCCCGGCAAGGAAGCCGCGCTCGGCTACGCCGACGTG
CGCACCGAACGGGCGGTGCTGGTCGGCTCCGCCAACACGCTGGTGCGTACCGAGACCGGCTGGCGGGCGGACTGCACCGA
CGTGGACGGCGTACTCGGCGCGCTGCGCGGCGGGGGAGTGACCGGCGTCGGCTCCGGCGTGGTGCTGGGCGCGGGCGGCA
CCGCGCGGCCCGCCCTGCTGGCGCTGCGGGAGCTGGGTGCGCGGTCGGTGACGATCGTGGCCAGGGACGAGGGCAGGGCG
CGCCCGGCCCGTGAACTCGCCGAGAAGCTCGGTCTGACCGTGACGGTCGCCGGTTTCGACCCGGACGGTGTGCGGGCCGC
GTGCGCGCAGGCCCAGGCGGTGGTCAGCACGATCCCGGCGGAAGCGGCGGCCACGATCGCGGCGGCCGTCGCCACCGCGC
CGGTGGTGCTCGACGCCATCTACAACCCGTGGCCGACGCCGTTGGCCACCGCGGTGGAGGCGGCCGGGCACACCGTCGTG
AGCGGTCTGCAGATGCTGCTCGAACAAGCCTATGGGCAGGTCGAGCAGTTCACCGGGCGTCCGGCGCCGCGCGGGGCGAT
GGCCGCGGCGCTGACCTCGTGA

Upstream 100 bases:

>100_bases
TTCGTCACGATCGACCAGAAGGGCACGACCCTGTTCACCGAGAGCTACGCCGAGCACCTGCGCAATATCGACAAGGCGAT
GGAAAGCGGGATCCTCGACA

Downstream 100 bases:

>100_bases
CGCCGCGGAATTTCTGACACGGGTTCTAGTTCTGTTCGGAACGTGCTGCGGTTAAGGTGGTCCCCATGAATGCTTGGGTC
GTGCGCGGGGTGCTGCTCGG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MGADATTPRRAAVLGKPIGHSRSPQLHLAAYRALGLDWTYDRIECDAAQLPGLVDGLGPEWVGLSVTMPGKEAALGYADV
RTERAVLVGSANTLVRTETGWRADCTDVDGVLGALRGGGVTGVGSGVVLGAGGTARPALLALRELGARSVTIVARDEGRA
RPARELAEKLGLTVTVAGFDPDGVRAACAQAQAVVSTIPAEAAATIAAAVATAPVVLDAIYNPWPTPLATAVEAAGHTVV
SGLQMLLEQAYGQVEQFTGRPAPRGAMAAALTS

Sequences:

>Translated_273_residues
MGADATTPRRAAVLGKPIGHSRSPQLHLAAYRALGLDWTYDRIECDAAQLPGLVDGLGPEWVGLSVTMPGKEAALGYADV
RTERAVLVGSANTLVRTETGWRADCTDVDGVLGALRGGGVTGVGSGVVLGAGGTARPALLALRELGARSVTIVARDEGRA
RPARELAEKLGLTVTVAGFDPDGVRAACAQAQAVVSTIPAEAAATIAAAVATAPVVLDAIYNPWPTPLATAVEAAGHTVV
SGLQMLLEQAYGQVEQFTGRPAPRGAMAAALTS
>Mature_272_residues
GADATTPRRAAVLGKPIGHSRSPQLHLAAYRALGLDWTYDRIECDAAQLPGLVDGLGPEWVGLSVTMPGKEAALGYADVR
TERAVLVGSANTLVRTETGWRADCTDVDGVLGALRGGGVTGVGSGVVLGAGGTARPALLALRELGARSVTIVARDEGRAR
PARELAEKLGLTVTVAGFDPDGVRAACAQAQAVVSTIPAEAAATIAAAVATAPVVLDAIYNPWPTPLATAVEAAGHTVVS
GLQMLLEQAYGQVEQFTGRPAPRGAMAAALTS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=269, Percent_Identity=30.8550185873606, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789675, Length=252, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=285, Percent_Identity=34.3859649122807, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27748; Mature: 27617

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGADATTPRRAAVLGKPIGHSRSPQLHLAAYRALGLDWTYDRIECDAAQLPGLVDGLGPE
CCCCCCCCCHHHHHCCCCCCCCCCCEEHHHHHHHCCCCCHHHEECCHHHCCHHHHCCCCC
WVGLSVTMPGKEAALGYADVRTERAVLVGSANTLVRTETGWRADCTDVDGVLGALRGGGV
CEEEEEECCCHHHHCCHHHHCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHCCCCC
TGVGSGVVLGAGGTARPALLALRELGARSVTIVARDEGRARPARELAEKLGLTVTVAGFD
CCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCC
PDGVRAACAQAQAVVSTIPAEAAATIAAAVATAPVVLDAIYNPWPTPLATAVEAAGHTVV
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHH
SGLQMLLEQAYGQVEQFTGRPAPRGAMAAALTS
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
GADATTPRRAAVLGKPIGHSRSPQLHLAAYRALGLDWTYDRIECDAAQLPGLVDGLGPE
CCCCCCCCHHHHHCCCCCCCCCCCEEHHHHHHHCCCCCHHHEECCHHHCCHHHHCCCCC
WVGLSVTMPGKEAALGYADVRTERAVLVGSANTLVRTETGWRADCTDVDGVLGALRGGGV
CEEEEEECCCHHHHCCHHHHCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHCCCCC
TGVGSGVVLGAGGTARPALLALRELGARSVTIVARDEGRARPARELAEKLGLTVTVAGFD
CCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEEECCC
PDGVRAACAQAQAVVSTIPAEAAATIAAAVATAPVVLDAIYNPWPTPLATAVEAAGHTVV
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHH
SGLQMLLEQAYGQVEQFTGRPAPRGAMAAALTS
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA