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The map label for this gene is pyrR [H]

Identifier: 54025594

GI number: 54025594

Start: 3837375

End: 3838001

Strand: Reverse

Name: pyrR [H]

Synonym: nfa36240

Alternate gene names: 54025594

Gene position: 3838001-3837375 (Counterclockwise)

Preceding gene: 54025595

Following gene: 54025593

Centisome position: 63.74

GC content: 71.77

Gene sequence:

>627_bases
ATGGCTGTGCCCGGAGATCGGGCCGCCAAGTCCGCCGAGCAGTCGCAGCGGCACACACCCGAATGGGTGGCCGCCGGGCG
GGAGCTGTTGTCGGCTTCCGATGTCGGCAGGACCGTCGCGCGGATGGCGCATCAGATCATCGAGAAGACCGCGCTGGACG
CGGGCGATGCCGGTGCTCCGCGGGTGGTGCTGATCGGCATCCCGACCCGCGGCACCACGTTGGCCGCGCGGCTCACCGAC
CGGATCGAGGAATTCTCCGGTGTGCGCCCCGCCCTCGGCTCGCTGGACATCACCCTGTACCGCGACGATCTGCGCACCCG
CCCGCACCGGCCGCTGGAACGGACCTCCGTGCCCGAGGGCGGCATCGAGGACGCGCTGGTGGTGCTGGTCGACGACGTGC
TCTTCTCCGGACGCACGGTGCGCTCGGCACTGGACGGCCTGCGCGATCTGGGCAGGCCGCGCGCGGTGCAGCTGGCCGTG
CTGGTCGACCGCGGCCACCGCGAGCTGCCGATCCGCGCCGACTACGTGGGCAAGAACGTGCCCACCTCCCGCAGCGAGGA
CATCTCGGTGCTGCTCACCGAGCACGACGGTCGCGACGGCGTCTACCTCCACCACGAGGAGGGCTAG

Upstream 100 bases:

>100_bases
CGCGTGTACCTGGTGAAAGCGCTGTCCGGAGCGCTGTTAGGCTGCTTGCCGTAAGACATCCTTTAACGGACCGTCCGGTG
AGGCGGGGAAGGAGGTCGGC

Downstream 100 bases:

>100_bases
CCGGTGCGACATCTGCTGAGCGTGACCGATCTGGATCGCACCGCCGCCACCGAGCTGCTCGACGAGGCCGAACGCTTCGA
ACAGGCGCTGCTCGGACGCG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MAVPGDRAAKSAEQSQRHTPEWVAAGRELLSASDVGRTVARMAHQIIEKTALDAGDAGAPRVVLIGIPTRGTTLAARLTD
RIEEFSGVRPALGSLDITLYRDDLRTRPHRPLERTSVPEGGIEDALVVLVDDVLFSGRTVRSALDGLRDLGRPRAVQLAV
LVDRGHRELPIRADYVGKNVPTSRSEDISVLLTEHDGRDGVYLHHEEG

Sequences:

>Translated_208_residues
MAVPGDRAAKSAEQSQRHTPEWVAAGRELLSASDVGRTVARMAHQIIEKTALDAGDAGAPRVVLIGIPTRGTTLAARLTD
RIEEFSGVRPALGSLDITLYRDDLRTRPHRPLERTSVPEGGIEDALVVLVDDVLFSGRTVRSALDGLRDLGRPRAVQLAV
LVDRGHRELPIRADYVGKNVPTSRSEDISVLLTEHDGRDGVYLHHEEG
>Mature_207_residues
AVPGDRAAKSAEQSQRHTPEWVAAGRELLSASDVGRTVARMAHQIIEKTALDAGDAGAPRVVLIGIPTRGTTLAARLTDR
IEEFSGVRPALGSLDITLYRDDLRTRPHRPLERTSVPEGGIEDALVVLVDDVLFSGRTVRSALDGLRDLGRPRAVQLAVL
VDRGHRELPIRADYVGKNVPTSRSEDISVLLTEHDGRDGVYLHHEEG

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 22614; Mature: 22483

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPGDRAAKSAEQSQRHTPEWVAAGRELLSASDVGRTVARMAHQIIEKTALDAGDAGAP
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RVVLIGIPTRGTTLAARLTDRIEEFSGVRPALGSLDITLYRDDLRTRPHRPLERTSVPEG
EEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHCCCCCC
GIEDALVVLVDDVLFSGRTVRSALDGLRDLGRPRAVQLAVLVDRGHRELPIRADYVGKNV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCC
PTSRSEDISVLLTEHDGRDGVYLHHEEG
CCCCCCCEEEEEEECCCCCCEEEEECCC
>Mature Secondary Structure 
AVPGDRAAKSAEQSQRHTPEWVAAGRELLSASDVGRTVARMAHQIIEKTALDAGDAGAP
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RVVLIGIPTRGTTLAARLTDRIEEFSGVRPALGSLDITLYRDDLRTRPHRPLERTSVPEG
EEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHCCCCCC
GIEDALVVLVDDVLFSGRTVRSALDGLRDLGRPRAVQLAVLVDRGHRELPIRADYVGKNV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCC
PTSRSEDISVLLTEHDGRDGVYLHHEEG
CCCCCCCEEEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA